Copper in PDB 6p1g: Copper-Bound Pcuac Domain From PMOF2

The structure of Copper-Bound Pcuac Domain From PMOF2, PDB code: 6p1g was solved by O.S.Fisher, A.C.Rosenzweig, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.85 / 2.05
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	89.350, 89.350, 60.070, 90.00, 90.00, 120.00
R / Rfree (%)	18.6 / 22.9

The structure of Copper-Bound Pcuac Domain From PMOF2 also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Copper atom in the Copper-Bound Pcuac Domain From PMOF2 (pdb code 6p1g). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 2 binding sites of Copper where determined in the Copper-Bound Pcuac Domain From PMOF2, PDB code: 6p1g:
Jump to Copper binding site number: 1; 2;

Copper binding site 1 out of 2 in the Copper-Bound Pcuac Domain From PMOF2


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Copper-Bound Pcuac Domain From PMOF2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu201 b:57.2 occ:1.00 ND1 A:HIS29 2.0 41.8 1.0 ND1 A:HIS40 2.1 40.8 1.0 N A:MET28 2.2 55.9 1.0 N A:HIS29 2.2 43.2 1.0 CE1 A:HIS29 2.9 42.7 1.0 C A:MET28 3.0 54.6 1.0 CG A:HIS40 3.0 38.9 1.0 CG A:HIS29 3.1 46.1 1.0 CA A:MET28 3.1 54.5 1.0 CE1 A:HIS40 3.1 43.2 1.0 CA A:HIS29 3.2 49.1 1.0 O A:HIS29 3.2 43.1 1.0 CB A:HIS40 3.3 35.5 1.0 CB A:HIS29 3.5 46.7 1.0 CA A:HIS40 3.5 36.8 1.0 C A:HIS29 3.6 51.5 1.0 NE2 A:HIS29 4.1 37.3 1.0 CD2 A:HIS29 4.1 42.6 1.0 O A:MET28 4.2 68.6 1.0 CD2 A:HIS40 4.2 44.6 1.0 CB A:MET28 4.2 55.2 1.0 NE2 A:HIS40 4.2 44.2 1.0 N A:HIS40 4.2 36.7 1.0 C A:HIS40 4.7 36.5 1.0 N A:GLU30 4.9 44.9 1.0

Copper binding site 2 out of 2 in the Copper-Bound Pcuac Domain From PMOF2


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Copper-Bound Pcuac Domain From PMOF2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cu201 b:44.7 occ:1.00 ND1 B:HIS29 2.0 37.7 1.0 N B:MET28 2.1 50.0 1.0 ND1 B:HIS40 2.1 34.6 1.0 N B:HIS29 2.2 35.2 1.0 CE1 B:HIS29 3.0 36.9 1.0 C B:MET28 3.0 48.9 1.0 CG B:HIS29 3.1 33.8 1.0 CG B:HIS40 3.1 34.6 1.0 CA B:MET28 3.1 52.4 1.0 CE1 B:HIS40 3.1 34.7 1.0 CA B:HIS29 3.2 43.3 1.0 O B:HIS29 3.2 38.1 1.0 CB B:HIS40 3.3 34.3 1.0 CB B:HIS29 3.4 38.0 1.0 CA B:HIS40 3.5 37.0 1.0 C B:HIS29 3.6 43.2 1.0 NE2 B:HIS29 4.1 38.1 1.0 CD2 B:HIS29 4.2 37.7 1.0 O B:MET28 4.2 55.1 1.0 CB B:MET28 4.2 46.9 1.0 CD2 B:HIS40 4.2 35.0 1.0 NE2 B:HIS40 4.2 36.4 1.0 N B:HIS40 4.3 34.4 1.0 C B:HIS40 4.7 31.4 1.0 N B:GLU30 4.9 37.6 1.0

O.S.Fisher, M.R.Sendzik, M.O.Ross, T.J.Lawton, B.M.Hoffman, A.C.Rosenzweig. Pcuac Domains From Methane-Oxidizing Bacteria Use A Histidine Brace to Bind Copper. J.Biol.Chem. V. 294 16351 2019.
ISSN: ESSN 1083-351X
PubMed: 31527086
DOI: 10.1074/JBC.RA119.010093