Copper in PDB 6lv9: Cu- Carbonic Anhydrase II pH 7.8 0 Atm CO2

All present enzymatic activity of Cu- Carbonic Anhydrase II pH 7.8 0 Atm CO2:
4.2.1.1;

The structure of Cu- Carbonic Anhydrase II pH 7.8 0 Atm CO2, PDB code: 6lv9 was solved by C.U.Kim, J.K.Kim, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 1.20
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.326, 41.225, 72.085, 90.00, 104.17, 90.00
R / Rfree (%)	11.7 / 14.4

The binding sites of Copper atom in the Cu- Carbonic Anhydrase II pH 7.8 0 Atm CO2 (pdb code 6lv9). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 2 binding sites of Copper where determined in the Cu- Carbonic Anhydrase II pH 7.8 0 Atm CO2, PDB code: 6lv9:
Jump to Copper binding site number: 1; 2;

Copper binding site 1 out of 2 in the Cu- Carbonic Anhydrase II pH 7.8 0 Atm CO2


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Cu- Carbonic Anhydrase II pH 7.8 0 Atm CO2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu302 b:6.6 occ:1.00 HD1 A:HIS119 1.2 5.6 1.0 HE2 A:HIS96 1.2 5.7 1.0 HE2 A:HIS94 1.3 5.3 1.0 ND1 A:HIS119 2.0 5.9 1.0 NE2 A:HIS96 2.0 5.8 1.0 NE2 A:HIS94 2.1 5.5 1.0 O A:HOH451 2.2 10.6 1.0 O A:HOH580 2.4 7.1 1.0 CE1 A:HIS119 2.9 5.3 1.0 CE1 A:HIS96 3.0 6.0 1.0 CD2 A:HIS96 3.0 5.8 1.0 CE1 A:HIS94 3.1 5.9 1.0 HE1 A:HIS119 3.1 5.2 1.0 CG A:HIS119 3.1 5.9 1.0 CD2 A:HIS94 3.1 5.6 1.0 HB2 A:HIS119 3.1 5.5 1.0 HD2 A:HIS96 3.2 5.6 1.0 HE1 A:HIS96 3.2 6.1 1.0 HE1 A:HIS94 3.2 5.5 1.0 HD2 A:HIS94 3.3 5.5 1.0 HG1 A:THR199 3.5 6.5 0.0 CB A:HIS119 3.5 5.5 1.0 HB3 A:HIS119 3.6 5.4 1.0 OG1 A:THR199 3.8 6.6 1.0 O A:HOH563 4.0 21.8 1.0 NE2 A:HIS119 4.1 5.5 1.0 OE1 A:GLU106 4.1 5.8 1.0 ND1 A:HIS96 4.1 6.7 1.0 HH2 A:TRP209 4.1 6.3 1.0 CD2 A:HIS119 4.2 5.1 1.0 ND1 A:HIS94 4.2 5.9 1.0 CG A:HIS96 4.2 5.8 1.0 CG A:HIS94 4.3 5.3 1.0 O A:HOH636 4.3 14.9 1.0 O A:HOH587 4.3 23.8 1.0 HE2 A:HIS119 4.8 5.0 1.0 H A:THR199 4.9 6.1 1.0 HG12 A:VAL143 4.9 7.0 1.0 HD1 A:HIS96 4.9 6.1 1.0 CA A:HIS119 4.9 4.7 1.0 HD1 A:HIS94 5.0 5.4 1.0 CD A:GLU106 5.0 5.5 1.0 HG23 A:THR199 5.0 7.0 1.0

Copper binding site 2 out of 2 in the Cu- Carbonic Anhydrase II pH 7.8 0 Atm CO2


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Cu- Carbonic Anhydrase II pH 7.8 0 Atm CO2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu303 b:21.9 occ:1.00 HD1 A:HIS4 1.2 36.7 1.0 H A:HIS4 1.4 21.4 1.0 N A:HIS4 1.8 24.3 1.0 ND1 A:HIS4 1.9 38.5 1.0 CG A:HIS4 2.9 33.0 1.0 H A:TRP5 3.0 15.7 1.0 CA A:HIS4 3.0 16.6 1.0 CE1 A:HIS4 3.0 43.1 1.0 CB A:HIS4 3.2 20.1 1.0 HE1 A:HIS4 3.2 41.7 1.0 HB3 A:HIS4 3.3 16.6 1.0 O A:HOH608 3.3 38.8 1.0 HA A:HIS4 3.6 18.5 1.0 N A:TRP5 3.7 14.4 1.0 C A:HIS4 3.9 21.2 1.0 CD2 A:HIS4 4.0 26.1 1.0 NE2 A:HIS4 4.0 35.2 1.0 HB2 A:HIS4 4.1 19.9 1.0 HD1 A:TRP5 4.7 10.5 1.0 O A:TRP5 4.7 12.1 1.0 HE2 A:HIS4 4.8 34.6 1.0 HD2 A:HIS4 4.9 26.8 1.0 CA A:TRP5 5.0 10.4 1.0

C.U.Kim, J.K.Kim. Metal Substituted Human Carbonic Anhydrase II Under CO2 Pressure To Be Published.