Copper in PDB 8dh6: Cryo-Em Structure of Saccharomyces Cerevisiae Cytochrome C Oxidase (Complex IV) Extracted in Lipid Nanodiscs

All present enzymatic activity of Cryo-Em Structure of Saccharomyces Cerevisiae Cytochrome C Oxidase (Complex IV) Extracted in Lipid Nanodiscs:
7.1.1.9;

The structure of Cryo-Em Structure of Saccharomyces Cerevisiae Cytochrome C Oxidase (Complex IV) Extracted in Lipid Nanodiscs also contains other interesting chemical elements:

Iron	(Fe)	2 atoms
Zinc	(Zn)	1 atom
Calcium	(Ca)	1 atom
Magnesium	(Mg)	1 atom

The binding sites of Copper atom in the Cryo-Em Structure of Saccharomyces Cerevisiae Cytochrome C Oxidase (Complex IV) Extracted in Lipid Nanodiscs (pdb code 8dh6). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 2 binding sites of Copper where determined in the Cryo-Em Structure of Saccharomyces Cerevisiae Cytochrome C Oxidase (Complex IV) Extracted in Lipid Nanodiscs, PDB code: 8dh6:
Jump to Copper binding site number: 1; 2;

Copper binding site 1 out of 2 in the Cryo-Em Structure of Saccharomyces Cerevisiae Cytochrome C Oxidase (Complex IV) Extracted in Lipid Nanodiscs


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Cryo-Em Structure of Saccharomyces Cerevisiae Cytochrome C Oxidase (Complex IV) Extracted in Lipid Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ a:Cu603 b:66.3 occ:1.00 ND1 a:HIS241 1.2 56.8 1.0 CE1 a:HIS241 1.8 56.8 1.0 NE2 a:HIS291 2.0 54.9 1.0 CG a:HIS241 2.5 56.8 1.0 CE1 a:HIS291 2.5 54.9 1.0 NE2 a:HIS290 2.6 55.0 1.0 NE2 a:HIS241 3.0 56.8 1.0 CD2 a:HIS291 3.2 54.9 1.0 CE1 a:HIS290 3.3 55.0 1.0 CD2 a:HIS241 3.3 56.8 1.0 CB a:HIS241 3.4 56.8 1.0 CD2 a:HIS290 3.7 55.0 1.0 ND1 a:HIS291 3.8 54.9 1.0 CA a:HIS241 4.0 56.8 1.0 CG a:HIS291 4.1 54.9 1.0 ND1 a:HIS290 4.5 55.0 1.0 FE a:HEA605 4.5 54.3 1.0 CG2 a:VAL244 4.6 54.4 1.0 C1A a:HEA605 4.7 54.3 1.0 CG a:HIS290 4.7 55.0 1.0 ND a:HEA605 4.7 54.3 1.0 NA a:HEA605 4.8 54.3 1.0 C4A a:HEA605 4.8 54.3 1.0 C2A a:HEA605 4.9 54.3 1.0 C4D a:HEA605 5.0 54.3 1.0

Copper binding site 2 out of 2 in the Cryo-Em Structure of Saccharomyces Cerevisiae Cytochrome C Oxidase (Complex IV) Extracted in Lipid Nanodiscs


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Cryo-Em Structure of Saccharomyces Cerevisiae Cytochrome C Oxidase (Complex IV) Extracted in Lipid Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ b:Cu303 b:69.9 occ:1.00 SG b:CYS225 1.5 63.5 1.0 SG b:CYS221 1.9 62.2 1.0 CE b:MET232 2.7 61.5 1.0 CD2 b:HIS229 3.1 58.2 1.0 CB b:CYS221 3.2 62.2 1.0 CB b:CYS225 3.3 63.5 1.0 O b:GLU223 3.4 60.5 1.0 CA b:HIS229 3.8 58.2 1.0 CG b:HIS229 3.8 58.2 1.0 ND1 b:HIS186 3.9 62.1 1.0 O b:HIS229 4.0 58.2 1.0 CB b:HIS229 4.0 58.2 1.0 NE2 b:HIS229 4.1 58.2 1.0 SD b:MET232 4.2 61.5 1.0 N b:CYS225 4.3 63.5 1.0 C b:HIS229 4.4 58.2 1.0 CA b:CYS225 4.5 63.5 1.0 CE1 b:HIS186 4.5 62.1 1.0 CA b:CYS221 4.5 62.2 1.0 C b:GLU223 4.6 60.5 1.0 O b:CYS221 4.7 62.2 1.0 O b:GLY228 4.8 60.2 1.0 N b:HIS229 4.8 58.2 1.0 CB b:MET232 4.8 61.5 1.0 C b:CYS221 4.9 62.2 1.0 C b:LEU224 4.9 58.6 1.0 CG b:HIS186 4.9 62.1 1.0

A.S.Godoy, Y.Song, H.Cheruvara, A.Quigley, G.Oliva. Cryo-Em Structure of Saccharomyces Cerevisiae Cytochrome C Oxidase (Complex IV) Extracted in Lipid Nanodiscs To Be Published.