Copper in PDB 7wwy: M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris)

All present enzymatic activity of M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris):
1.15.1.1;

The structure of M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris), PDB code: 7wwy was solved by S.Narikiyo, Y.Furukawa, M.Akutsu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.71 / 1.50
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	50.643, 50.643, 282.12, 90, 90, 90
R / Rfree (%)	25.6 / 28.7

The structure of M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris) also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Copper atom in the M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris) (pdb code 7wwy). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 2 binding sites of Copper where determined in the M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris), PDB code: 7wwy:
Jump to Copper binding site number: 1; 2;

Copper binding site 1 out of 2 in the M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris)


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu202 b:22.6 occ:1.00 ND1 A:HIS46 2.0 18.8 1.0 CE1 A:HIS48 2.0 21.0 1.0 CE1 A:HIS120 2.0 17.6 1.0 NE2 A:HIS48 2.9 20.6 1.0 NE2 A:HIS120 2.9 26.4 1.0 CE1 A:HIS46 2.9 20.9 1.0 CG A:HIS46 3.0 20.1 1.0 ND1 A:HIS120 3.0 22.2 1.0 ND1 A:HIS48 3.1 21.6 1.0 NE2 A:HIS63 3.1 20.4 1.0 CB A:HIS46 3.3 22.5 1.0 O A:HOH344 3.4 24.8 1.0 CD2 A:HIS63 3.5 19.2 1.0 CB A:VAL118 4.0 22.6 1.0 NE2 A:HIS46 4.1 21.4 1.0 CE1 A:HIS63 4.1 18.7 1.0 CD2 A:HIS48 4.1 16.8 1.0 CD2 A:HIS120 4.1 18.4 1.0 CD2 A:HIS46 4.1 19.1 1.0 CG1 A:VAL118 4.1 23.1 1.0 CG A:HIS120 4.1 20.2 1.0 CG A:HIS48 4.2 18.5 1.0 CA A:HIS46 4.2 19.5 1.0 N A:HIS46 4.3 21.0 1.0 O A:VAL118 4.5 20.6 1.0 O A:HIS46 4.6 17.7 1.0 CG2 A:VAL118 4.6 19.9 1.0 CG A:HIS63 4.6 16.5 1.0 C A:HIS46 4.7 20.2 1.0 ND1 A:HIS63 4.9 15.4 1.0

Copper binding site 2 out of 2 in the M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris)


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cu202 b:35.3 occ:1.00 NE2 B:HIS120 2.0 37.6 1.0 NE2 B:HIS48 2.1 27.9 1.0 ND1 B:HIS46 2.2 31.5 1.0 CD2 B:HIS120 2.8 34.3 1.0 CD2 B:HIS48 3.0 35.3 1.0 CG B:HIS46 3.0 28.6 1.0 CE1 B:HIS48 3.1 33.9 1.0 CE1 B:HIS120 3.1 35.1 1.0 CB B:HIS46 3.2 28.0 1.0 CE1 B:HIS46 3.3 31.2 1.0 O B:HOH304 3.5 31.1 1.0 NE2 B:HIS63 3.6 32.3 1.0 CD2 B:HIS63 3.8 32.8 1.0 CB B:VAL118 4.0 25.9 1.0 CG B:HIS120 4.0 33.1 1.0 ND1 B:HIS120 4.1 35.6 1.0 CA B:HIS46 4.1 27.4 1.0 N B:HIS46 4.1 26.8 1.0 CG B:HIS48 4.2 30.2 1.0 ND1 B:HIS48 4.2 30.0 1.0 CD2 B:HIS46 4.2 33.3 1.0 NE2 B:HIS46 4.3 30.8 1.0 CG1 B:VAL118 4.3 23.4 1.0 O B:HIS46 4.4 24.5 1.0 CE1 B:HIS63 4.5 33.4 1.0 O B:VAL118 4.5 25.7 1.0 C B:HIS46 4.6 23.0 1.0 CG2 B:VAL118 4.7 24.5 1.0 O B:HOH357 4.7 34.8 1.0 CG B:HIS63 4.8 34.7 1.0 C B:VAL118 4.8 23.5 1.0 CA B:VAL118 5.0 25.7 1.0

S.Narikiyo, Y.Furukawa, M.Akutsu. Crystal Structure of Dog Superoxide Dismutase To Be Published.