Copper in PDB 8uco: Cryoem Structure of Komagataella Pastoris Cytochrome C Oxidase (9 Subunits) in Complex with Human VMAT2 and Amphetamine

The structure of Cryoem Structure of Komagataella Pastoris Cytochrome C Oxidase (9 Subunits) in Complex with Human VMAT2 and Amphetamine also contains other interesting chemical elements:

Zinc	(Zn)	1 atom
Iron	(Fe)	2 atoms

The binding sites of Copper atom in the Cryoem Structure of Komagataella Pastoris Cytochrome C Oxidase (9 Subunits) in Complex with Human VMAT2 and Amphetamine (pdb code 8uco). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 3 binding sites of Copper where determined in the Cryoem Structure of Komagataella Pastoris Cytochrome C Oxidase (9 Subunits) in Complex with Human VMAT2 and Amphetamine, PDB code: 8uco:
Jump to Copper binding site number: 1; 2; 3;

Copper binding site 1 out of 3 in the Cryoem Structure of Komagataella Pastoris Cytochrome C Oxidase (9 Subunits) in Complex with Human VMAT2 and Amphetamine


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Cryoem Structure of Komagataella Pastoris Cytochrome C Oxidase (9 Subunits) in Complex with Human VMAT2 and Amphetamine within 5.0Å range: probe atom residue distance (Å) B Occ a:Cu601 b:46.8 occ:1.00 ND1 a:HIS243 2.1 42.4 1.0 NE2 a:HIS293 2.1 42.8 1.0 CE1 a:HIS243 2.4 42.4 1.0 NE2 a:HIS292 2.8 43.9 1.0 CE1 a:HIS293 2.9 42.8 1.0 CHA a:HEA603 3.1 46.0 1.0 CD2 a:HIS293 3.2 42.8 1.0 C1A a:HEA603 3.4 46.0 1.0 CG a:HIS243 3.4 42.4 1.0 NA a:HEA603 3.6 46.0 1.0 CD2 a:HIS292 3.7 43.9 1.0 FE a:HEA603 3.7 46.0 1.0 NE2 a:HIS243 3.7 42.4 1.0 CE1 a:HIS292 3.7 43.9 1.0 C4D a:HEA603 3.8 46.0 1.0 ND1 a:HIS293 4.0 42.8 1.0 ND a:HEA603 4.1 46.0 1.0 CD2 a:HIS243 4.2 42.4 1.0 CB a:HIS243 4.2 42.4 1.0 CG a:HIS293 4.2 42.8 1.0 C2A a:HEA603 4.2 46.0 1.0 C4A a:HEA603 4.5 46.0 1.0 CA a:HIS243 4.6 42.4 1.0 CG2 a:VAL246 4.7 41.8 1.0 NB a:HEA603 4.8 46.0 1.0 CG a:HIS292 4.8 43.9 1.0 ND1 a:HIS292 4.8 43.9 1.0 C3A a:HEA603 4.8 46.0 1.0 CAA a:HEA603 4.9 46.0 1.0 C3D a:HEA603 4.9 46.0 1.0

Copper binding site 2 out of 3 in the Cryoem Structure of Komagataella Pastoris Cytochrome C Oxidase (9 Subunits) in Complex with Human VMAT2 and Amphetamine


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Cryoem Structure of Komagataella Pastoris Cytochrome C Oxidase (9 Subunits) in Complex with Human VMAT2 and Amphetamine within 5.0Å range: probe atom residue distance (Å) B Occ b:Cu301 b:61.6 occ:1.00 CU1 b:CUA301 0.0 61.6 1.0 CU2 b:CUA301 1.7 61.6 1.0 SG b:CYS219 3.0 49.5 1.0 SG b:CYS223 3.0 51.0 1.0 ND1 b:HIS227 3.2 47.1 1.0 CD2 b:HIS184 3.4 47.0 1.0 SD b:MET230 3.4 48.6 1.0 CB b:CYS223 3.5 51.0 1.0 O b:GLU221 3.6 49.0 1.0 CB b:CYS219 3.8 49.5 1.0 CE b:MET230 4.0 48.6 1.0 CE1 b:HIS227 4.1 47.1 1.0 NE2 b:HIS184 4.1 47.0 1.0 CG b:HIS227 4.2 47.1 1.0 O b:HIS227 4.3 47.1 1.0 CG b:HIS184 4.3 47.0 1.0 CA b:HIS227 4.3 47.1 1.0 CB b:HIS227 4.4 47.1 1.0 N b:CYS223 4.4 51.0 1.0 CA b:CYS223 4.6 51.0 1.0 CB b:HIS184 4.8 47.0 1.0 C b:GLU221 4.8 49.0 1.0 C b:HIS227 4.8 47.1 1.0 CG b:MET230 4.9 48.6 1.0 O b:GLN121 5.0 50.5 1.0

Copper binding site 3 out of 3 in the Cryoem Structure of Komagataella Pastoris Cytochrome C Oxidase (9 Subunits) in Complex with Human VMAT2 and Amphetamine


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 3 of Cryoem Structure of Komagataella Pastoris Cytochrome C Oxidase (9 Subunits) in Complex with Human VMAT2 and Amphetamine within 5.0Å range: probe atom residue distance (Å) B Occ b:Cu301 b:61.6 occ:1.00 CU2 b:CUA301 0.0 61.6 1.0 CU1 b:CUA301 1.7 61.6 1.0 CB b:CYS223 2.9 51.0 1.0 SD b:MET230 3.0 48.6 1.0 CD2 b:HIS184 3.0 47.0 1.0 SG b:CYS223 3.2 51.0 1.0 NE2 b:HIS184 3.2 47.0 1.0 O b:GLN121 3.4 50.5 1.0 CE b:MET230 3.9 48.6 1.0 CD1 b:TRP122 4.2 49.9 1.0 CA b:CYS223 4.2 51.0 1.0 CG b:HIS184 4.2 47.0 1.0 CE1 b:HIS184 4.4 47.0 1.0 CA b:HIS227 4.4 47.1 1.0 ND1 b:HIS227 4.4 47.1 1.0 NE1 b:TRP122 4.5 49.9 1.0 N b:CYS223 4.5 51.0 1.0 C b:GLN121 4.6 50.5 1.0 CG b:MET230 4.6 48.6 1.0 CB b:HIS227 4.6 47.1 1.0 SG b:CYS219 4.6 49.5 1.0 C b:CYS223 4.7 51.0 1.0 O b:MET226 4.7 49.4 1.0 O b:GLU221 4.9 49.0 1.0 ND1 b:HIS184 4.9 47.0 1.0 O b:CYS223 4.9 51.0 1.0 CG b:HIS227 5.0 47.1 1.0

J.Ye, B.Liu, W.Li. Cryoem Structure of Komagataella Pastoris Cytochrome C Oxidase (9 Subunits) in Complex with Human VMAT2 and Amphetamin To Be Published.