Copper in PDB 8ucn: Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Histamine

The structure of Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Histamine also contains other interesting chemical elements:

Zinc	(Zn)	1 atom
Iron	(Fe)	2 atoms

The binding sites of Copper atom in the Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Histamine (pdb code 8ucn). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 3 binding sites of Copper where determined in the Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Histamine, PDB code: 8ucn:
Jump to Copper binding site number: 1; 2; 3;

Copper binding site 1 out of 3 in the Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Histamine


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Histamine within 5.0Å range: probe atom residue distance (Å) B Occ a:Cu601 b:54.9 occ:1.00 ND1 a:HIS243 2.1 47.6 1.0 NE2 a:HIS292 2.2 49.0 1.0 CE1 a:HIS293 2.3 47.6 1.0 NE2 a:HIS293 2.3 47.6 1.0 CE1 a:HIS243 2.5 47.6 1.0 CHA a:HEA603 2.9 51.2 1.0 CD2 a:HIS292 3.0 49.0 1.0 C1A a:HEA603 3.2 51.2 1.0 CE1 a:HIS292 3.3 49.0 1.0 CG a:HIS243 3.4 47.6 1.0 ND1 a:HIS293 3.4 47.6 1.0 CD2 a:HIS293 3.5 47.6 1.0 NA a:HEA603 3.7 51.2 1.0 NE2 a:HIS243 3.8 47.6 1.0 C4D a:HEA603 3.9 51.2 1.0 FE a:HEA603 4.0 51.2 1.0 C2A a:HEA603 4.0 51.2 1.0 CG a:HIS293 4.0 47.6 1.0 CB a:HIS243 4.1 47.6 1.0 CD2 a:HIS243 4.2 47.6 1.0 CG a:HIS292 4.3 49.0 1.0 ND1 a:HIS292 4.3 49.0 1.0 ND a:HEA603 4.4 51.2 1.0 CAA a:HEA603 4.6 51.2 1.0 C4A a:HEA603 4.6 51.2 1.0 CA a:HIS243 4.7 47.6 1.0 C3A a:HEA603 4.7 51.2 1.0

Copper binding site 2 out of 3 in the Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Histamine


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Histamine within 5.0Å range: probe atom residue distance (Å) B Occ b:Cu301 b:66.1 occ:1.00 CU1 b:CUA301 0.0 66.1 1.0 CU2 b:CUA301 1.7 66.1 1.0 SG b:CYS223 2.4 53.5 1.0 SG b:CYS219 2.5 52.6 1.0 SD b:MET230 3.4 51.5 1.0 O b:GLU221 3.4 53.5 1.0 CD2 b:HIS227 3.4 49.8 1.0 CB b:CYS219 3.4 52.6 1.0 CD2 b:HIS184 3.6 51.0 1.0 CB b:CYS223 3.8 53.5 1.0 CE b:MET230 3.9 51.5 1.0 NE2 b:HIS227 4.2 49.8 1.0 CG b:HIS184 4.3 51.0 1.0 NE2 b:HIS184 4.4 51.0 1.0 CG b:HIS227 4.5 49.8 1.0 C b:GLU221 4.6 53.5 1.0 CB b:HIS184 4.6 51.0 1.0 O b:HIS227 4.6 49.8 1.0 N b:CYS223 4.6 53.5 1.0 CA b:HIS184 4.7 51.0 1.0 CA b:HIS227 4.8 49.8 1.0 CG b:MET230 4.9 51.5 1.0 CA b:CYS219 4.9 52.6 1.0 CA b:CYS223 4.9 53.5 1.0 CB b:HIS227 5.0 49.8 1.0

Copper binding site 3 out of 3 in the Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Histamine


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 3 of Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Histamine within 5.0Å range: probe atom residue distance (Å) B Occ b:Cu301 b:66.1 occ:1.00 CU2 b:CUA301 0.0 66.1 1.0 CU1 b:CUA301 1.7 66.1 1.0 SD b:MET230 2.4 51.5 1.0 CE b:MET230 2.5 51.5 1.0 CD2 b:HIS184 2.6 51.0 1.0 SG b:CYS223 2.9 53.5 1.0 NE2 b:HIS184 3.1 51.0 1.0 O b:GLN121 3.6 53.7 1.0 CG b:HIS184 3.7 51.0 1.0 CB b:CYS223 3.7 53.5 1.0 SG b:CYS219 3.9 52.6 1.0 CG b:MET230 4.1 51.5 1.0 CE1 b:HIS184 4.3 51.0 1.0 CB b:CYS219 4.5 52.6 1.0 CB b:HIS184 4.5 51.0 1.0 CB b:MET230 4.6 51.5 1.0 ND1 b:HIS184 4.6 51.0 1.0 O b:LEU120 4.7 52.2 1.0 C b:GLN121 4.8 53.7 1.0 CD2 b:HIS227 4.8 49.8 1.0 O b:GLU221 4.9 53.5 1.0

J.Ye, B.Liu, W.Li. Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Histamine To Be Published.