Copper in PDB 8ucm: Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Reserpine

The structure of Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Reserpine also contains other interesting chemical elements:

Iron	(Fe)	2 atoms
Zinc	(Zn)	1 atom

The binding sites of Copper atom in the Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Reserpine (pdb code 8ucm). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 3 binding sites of Copper where determined in the Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Reserpine, PDB code: 8ucm:
Jump to Copper binding site number: 1; 2; 3;

Copper binding site 1 out of 3 in the Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Reserpine


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Reserpine within 5.0Å range: probe atom residue distance (Å) B Occ a:Cu601 b:46.9 occ:1.00 ND1 a:HIS243 2.0 40.6 1.0 NE2 a:HIS292 2.1 41.5 1.0 CE1 a:HIS293 2.3 40.4 1.0 CE1 a:HIS243 2.5 40.6 1.0 NE2 a:HIS293 2.6 40.4 1.0 CE1 a:HIS292 3.1 41.5 1.0 CD2 a:HIS292 3.1 41.5 1.0 CHA a:HEA603 3.1 43.2 1.0 CG a:HIS243 3.2 40.6 1.0 C1A a:HEA603 3.3 43.2 1.0 ND1 a:HIS293 3.4 40.4 1.0 NE2 a:HIS243 3.7 40.6 1.0 NA a:HEA603 3.7 43.2 1.0 CD2 a:HIS293 3.8 40.4 1.0 FE a:HEA603 3.9 43.2 1.0 C4D a:HEA603 3.9 43.2 1.0 CB a:HIS243 4.0 40.6 1.0 CD2 a:HIS243 4.0 40.6 1.0 C2A a:HEA603 4.1 43.2 1.0 CG a:HIS293 4.2 40.4 1.0 ND1 a:HIS292 4.2 41.5 1.0 CG a:HIS292 4.2 41.5 1.0 ND a:HEA603 4.3 43.2 1.0 C4A a:HEA603 4.5 43.2 1.0 CA a:HIS243 4.5 40.6 1.0 C3A a:HEA603 4.7 43.2 1.0 CAA a:HEA603 4.7 43.2 1.0 NB a:HEA603 4.9 43.2 1.0 CG2 a:VAL246 5.0 40.3 1.0

Copper binding site 2 out of 3 in the Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Reserpine


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Reserpine within 5.0Å range: probe atom residue distance (Å) B Occ b:Cu301 b:56.7 occ:1.00 CU1 b:CUA301 0.0 56.7 1.0 CU2 b:CUA301 1.7 56.7 1.0 SG b:CYS223 2.1 45.5 1.0 SG b:CYS219 2.5 43.6 1.0 ND1 b:HIS227 3.1 42.7 1.0 O b:GLU221 3.3 45.0 1.0 CB b:CYS219 3.5 43.6 1.0 CB b:CYS223 3.5 45.5 1.0 SD b:MET230 3.6 43.7 1.0 CD2 b:HIS184 4.0 43.0 1.0 CG b:HIS227 4.0 42.7 1.0 CE1 b:HIS227 4.0 42.7 1.0 CB b:HIS227 4.1 42.7 1.0 CA b:HIS227 4.2 42.7 1.0 N b:CYS223 4.3 45.5 1.0 O b:HIS227 4.3 42.7 1.0 CA b:CYS223 4.5 45.5 1.0 C b:GLU221 4.6 45.0 1.0 CG b:HIS184 4.6 43.0 1.0 CG b:MET230 4.7 43.7 1.0 NE2 b:HIS184 4.7 43.0 1.0 C b:HIS227 4.8 42.7 1.0 C b:LEU222 4.8 43.8 1.0 CB b:MET230 4.9 43.7 1.0 CA b:CYS219 4.9 43.6 1.0 CB b:HIS184 4.9 43.0 1.0 CA b:HIS184 5.0 43.0 1.0

Copper binding site 3 out of 3 in the Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Reserpine


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 3 of Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Reserpine within 5.0Å range: probe atom residue distance (Å) B Occ b:Cu301 b:56.7 occ:1.00 CU2 b:CUA301 0.0 56.7 1.0 CU1 b:CUA301 1.7 56.7 1.0 SD b:MET230 2.3 43.7 1.0 CD2 b:HIS184 2.6 43.0 1.0 SG b:CYS223 2.7 45.5 1.0 SG b:CYS219 3.2 43.6 1.0 NE2 b:HIS184 3.4 43.0 1.0 CE b:MET230 3.5 43.7 1.0 CG b:HIS184 3.5 43.0 1.0 CB b:CYS223 3.8 45.5 1.0 CG b:MET230 3.8 43.7 1.0 O b:GLN121 3.9 44.9 1.0 CB b:CYS219 4.0 43.6 1.0 CB b:HIS184 4.1 43.0 1.0 CB b:MET230 4.3 43.7 1.0 CE1 b:HIS184 4.5 43.0 1.0 ND1 b:HIS184 4.6 43.0 1.0 CA b:HIS184 4.7 43.0 1.0 ND1 b:HIS227 4.7 42.7 1.0 O b:GLU221 4.8 45.0 1.0 O b:LEU120 4.9 43.9 1.0

J.Ye, B.Liu, W.Li. Komagataella Pastoris Cytochrome C Oxidase in Complex with Human VMAT2 and Reserpine To Be Published.