Copper in PDB 8r4h: Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain

The structure of Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain, PDB code: 8r4h was solved by P.Leone, U.Contaldo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.23 / 2.94
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	169.273, 169.273, 90.387, 90, 90, 120
R / Rfree (%)	19.8 / 24.5

The binding sites of Copper atom in the Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain (pdb code 8r4h). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 8 binding sites of Copper where determined in the Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain, PDB code: 8r4h:
Jump to Copper binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Copper binding site 1 out of 8 in the Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu601 b:75.5 occ:1.00 ND1 A:HIS105 1.9 57.8 1.0 NE2 A:HIS143 1.9 58.0 1.0 NE2 A:HIS525 2.3 64.8 1.0 CE1 A:HIS143 2.6 58.1 1.0 CE1 A:HIS105 2.7 58.1 1.0 CG A:HIS105 3.0 57.1 1.0 CD2 A:HIS143 3.1 57.0 1.0 CE1 A:HIS525 3.2 64.6 1.0 CD2 A:HIS525 3.2 63.8 1.0 CB A:HIS105 3.5 57.0 1.0 CD2 A:HIS103 3.8 67.3 1.0 CZ2 A:TRP141 3.8 50.6 1.0 ND1 A:HIS143 3.8 57.8 1.0 NE2 A:HIS105 3.9 58.3 1.0 CD2 A:HIS105 4.0 57.7 1.0 CG A:HIS143 4.0 56.1 1.0 CU A:CU602 4.1 101.1 1.0 CE2 A:TRP141 4.1 50.2 1.0 CD2 A:HIS470 4.2 61.7 1.0 NE2 A:HIS470 4.2 62.3 1.0 NE1 A:TRP141 4.2 50.6 1.0 NE2 A:HIS103 4.3 68.6 1.0 CG A:HIS525 4.4 63.1 1.0 ND1 A:HIS525 4.4 64.2 1.0 CU A:CU603 4.5 101.5 0.5 CH2 A:TRP141 4.6 50.4 1.0 CA A:HIS105 4.6 57.2 1.0

Copper binding site 2 out of 8 in the Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu602 b:101.1 occ:1.00 NE2 A:HIS523 2.0 73.3 1.0 NE2 A:HIS472 2.2 67.3 1.0 NE2 A:HIS145 2.3 63.2 1.0 CE1 A:HIS523 2.7 73.6 1.0 CD2 A:HIS145 2.9 62.0 1.0 CE1 A:HIS472 3.0 67.4 1.0 CD2 A:HIS523 3.3 72.2 1.0 CD2 A:HIS472 3.3 66.3 1.0 CD2 A:HIS470 3.4 61.7 1.0 CE1 A:HIS145 3.5 63.1 1.0 CD2 A:HIS103 3.7 67.3 1.0 CU A:CU603 3.7 101.5 0.5 NE2 A:HIS103 3.8 68.6 1.0 NE2 A:HIS470 3.9 62.3 1.0 ND1 A:HIS523 3.9 73.0 1.0 CU A:CU601 4.1 75.5 1.0 CG A:HIS145 4.2 60.5 1.0 ND1 A:HIS472 4.2 66.9 1.0 CG A:HIS523 4.2 71.3 1.0 CG A:HIS472 4.3 65.2 1.0 ND1 A:HIS145 4.5 62.4 1.0 CG A:HIS103 4.5 65.7 1.0 CD2 A:HIS525 4.5 63.8 1.0 CG A:HIS470 4.6 61.3 1.0 CE1 A:HIS103 4.6 68.4 1.0 NE2 A:HIS525 4.6 64.8 1.0 CE1 A:HIS143 4.7 58.1 1.0 OE1 A:GLU530 4.7 72.5 1.0 OE2 A:GLU530 4.7 73.6 1.0 ND1 A:HIS105 4.9 57.8 1.0 NE2 A:HIS143 4.9 58.0 1.0 CD A:GLU530 5.0 71.6 1.0

Copper binding site 3 out of 8 in the Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 3 of Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu603 b:101.5 occ:0.50 NE2 A:HIS470 1.7 62.3 1.0 NE2 A:HIS103 2.0 68.6 1.0 CE1 A:HIS470 2.7 62.6 1.0 CE1 A:HIS103 2.8 68.4 1.0 CD2 A:HIS470 2.8 61.7 1.0 CD2 A:HIS472 3.2 66.3 1.0 CD2 A:HIS103 3.2 67.3 1.0 NE2 A:HIS472 3.4 67.3 1.0 CG A:HIS472 3.6 65.2 1.0 CU A:CU602 3.7 101.1 1.0 CE1 A:HIS472 3.8 67.4 1.0 CA A:HIS105 3.8 57.2 1.0 ND1 A:HIS470 3.8 62.6 1.0 CG A:HIS470 3.8 61.3 1.0 ND1 A:HIS105 3.9 57.8 1.0 ND1 A:HIS472 3.9 66.9 1.0 CG A:HIS105 3.9 57.1 1.0 ND1 A:HIS103 4.0 67.6 1.0 CA A:HIS472 4.1 63.7 1.0 CG A:HIS103 4.2 65.7 1.0 N A:GLY106 4.2 57.1 1.0 CB A:HIS105 4.2 57.0 1.0 CB A:HIS472 4.3 63.8 1.0 CE1 A:HIS105 4.3 58.1 1.0 CD2 A:HIS105 4.5 57.7 1.0 CU A:CU601 4.5 75.5 1.0 N A:HIS472 4.5 63.0 1.0 C A:HIS105 4.6 57.3 1.0 O A:ILE471 4.6 63.3 1.0 N A:HIS105 4.6 57.7 1.0 NE2 A:HIS105 4.7 58.3 1.0 C A:ILE471 4.7 62.8 1.0

Copper binding site 4 out of 8 in the Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 4 of Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu604 b:75.7 occ:1.00 ND1 A:HIS467 1.8 74.2 1.0 ND1 A:HIS529 1.9 63.2 1.0 SG A:CYS524 2.1 67.4 1.0 CE1 A:HIS467 2.5 74.7 1.0 CE1 A:HIS529 2.8 63.5 1.0 CG A:HIS529 3.0 61.5 1.0 CG A:HIS467 3.0 72.5 1.0 CB A:CYS524 3.3 65.6 1.0 CB A:HIS529 3.4 60.6 1.0 SD A:MET534 3.4 73.0 1.0 O A:LEU466 3.5 73.8 1.0 CB A:HIS467 3.7 70.8 1.0 NE2 A:HIS467 3.7 74.7 1.0 CA A:HIS467 3.9 70.7 1.0 CE A:MET534 3.9 68.0 1.0 CD2 A:HIS467 4.0 73.5 1.0 NE2 A:HIS529 4.0 63.3 1.0 CB A:LEU526 4.0 60.6 1.0 CD2 A:HIS529 4.1 62.2 1.0 C A:LEU466 4.3 73.7 1.0 CD1 A:LEU526 4.5 61.0 1.0 N A:HIS467 4.5 71.8 1.0 CA A:CYS524 4.6 65.5 1.0 CG A:LEU526 4.8 60.7 1.0 CG A:MET534 4.9 70.4 1.0 CA A:HIS529 4.9 60.7 1.0

Copper binding site 5 out of 8 in the Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 5 of Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Cu601 b:87.7 occ:1.00 ND1 B:HIS105 1.8 66.9 1.0 NE2 B:HIS143 1.9 69.3 1.0 NE2 B:HIS525 2.4 78.8 1.0 CE1 B:HIS143 2.6 69.5 1.0 CE1 B:HIS105 2.8 67.2 1.0 CG B:HIS105 2.9 65.3 1.0 CD2 B:HIS143 3.1 68.1 1.0 CD2 B:HIS525 3.3 77.9 1.0 CE1 B:HIS525 3.4 78.9 1.0 CB B:HIS105 3.4 63.6 1.0 CD2 B:HIS103 3.7 71.7 1.0 ND1 B:HIS143 3.9 68.7 1.0 CZ2 B:TRP141 3.9 62.7 1.0 NE2 B:HIS105 3.9 67.1 1.0 CU B:CU602 4.0 105.4 1.0 CD2 B:HIS105 4.0 66.3 1.0 CG B:HIS143 4.1 66.8 1.0 NE2 B:HIS470 4.1 71.2 1.0 NE2 B:HIS103 4.1 73.0 1.0 CD2 B:HIS470 4.1 70.1 1.0 CE2 B:TRP141 4.2 62.3 1.0 NE1 B:TRP141 4.2 62.7 1.0 CU B:CU603 4.4 82.6 0.5 CG B:HIS525 4.5 76.8 1.0 ND1 B:HIS525 4.5 78.4 1.0 CA B:HIS105 4.5 62.8 1.0 CH2 B:TRP141 4.7 62.5 1.0 CG B:HIS103 4.9 70.3 1.0 CE1 B:HIS470 5.0 71.5 1.0 CG B:HIS470 5.0 69.3 1.0

Copper binding site 6 out of 8 in the Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 6 of Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Cu602 b:105.4 occ:1.00 NE2 B:HIS523 2.0 83.0 1.0 NE2 B:HIS472 2.2 64.5 1.0 NE2 B:HIS145 2.3 73.1 1.0 CE1 B:HIS523 2.6 83.1 1.0 CD2 B:HIS145 2.9 71.7 1.0 CE1 B:HIS472 3.0 64.5 1.0 CD2 B:HIS523 3.3 81.8 1.0 CD2 B:HIS472 3.4 63.7 1.0 CD2 B:HIS470 3.4 70.1 1.0 CU B:CU603 3.5 82.6 0.5 CE1 B:HIS145 3.5 73.1 1.0 CD2 B:HIS103 3.7 71.7 1.0 NE2 B:HIS103 3.8 73.0 1.0 NE2 B:HIS470 3.9 71.2 1.0 ND1 B:HIS523 3.9 82.4 1.0 CU B:CU601 4.0 87.7 1.0 CG B:HIS145 4.2 70.1 1.0 ND1 B:HIS472 4.2 64.2 1.0 CG B:HIS523 4.2 80.6 1.0 CG B:HIS472 4.3 63.0 1.0 ND1 B:HIS145 4.5 72.3 1.0 CG B:HIS103 4.5 70.3 1.0 CD2 B:HIS525 4.6 77.9 1.0 CG B:HIS470 4.6 69.3 1.0 CE1 B:HIS103 4.6 73.0 1.0 NE2 B:HIS525 4.6 78.8 1.0 CE1 B:HIS143 4.7 69.5 1.0 OE2 B:GLU530 4.8 83.2 1.0 ND1 B:HIS105 4.9 66.9 1.0 NE2 B:HIS143 4.9 69.3 1.0

Copper binding site 7 out of 8 in the Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 7 of Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Cu603 b:82.6 occ:0.50 NE2 B:HIS470 1.8 71.2 1.0 NE2 B:HIS103 1.9 73.0 1.0 CE1 B:HIS103 2.7 73.0 1.0 CD2 B:HIS470 2.7 70.1 1.0 CE1 B:HIS470 2.8 71.5 1.0 CD2 B:HIS472 3.0 63.7 1.0 CD2 B:HIS103 3.1 71.7 1.0 NE2 B:HIS472 3.1 64.5 1.0 CG B:HIS472 3.4 63.0 1.0 CU B:CU602 3.5 105.4 1.0 CE1 B:HIS472 3.6 64.5 1.0 ND1 B:HIS472 3.7 64.2 1.0 CG B:HIS470 3.9 69.3 1.0 ND1 B:HIS103 3.9 72.3 1.0 ND1 B:HIS105 3.9 66.9 1.0 ND1 B:HIS470 3.9 71.0 1.0 CA B:HIS105 4.0 62.8 1.0 CG B:HIS103 4.1 70.3 1.0 CA B:HIS472 4.1 64.5 1.0 CG B:HIS105 4.1 65.3 1.0 CB B:HIS472 4.2 63.5 1.0 CU B:CU601 4.4 87.7 1.0 CB B:HIS105 4.4 63.6 1.0 CE1 B:HIS105 4.4 67.2 1.0 N B:GLY106 4.5 62.2 1.0 N B:HIS472 4.5 65.1 1.0 O B:ILE471 4.7 67.3 1.0 CD2 B:HIS105 4.7 66.3 1.0 N B:HIS105 4.8 63.0 1.0 C B:ILE471 4.8 66.3 1.0 C B:HIS105 4.8 62.6 1.0 NE2 B:HIS105 4.8 67.1 1.0 NE2 B:HIS523 4.9 83.0 1.0

Copper binding site 8 out of 8 in the Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 8 of Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Cu604 b:83.6 occ:1.00 ND1 B:HIS467 1.8 80.9 1.0 ND1 B:HIS529 1.9 70.7 1.0 SG B:CYS524 2.1 80.2 1.0 CE1 B:HIS467 2.5 81.5 1.0 CE1 B:HIS529 2.8 70.9 1.0 CG B:HIS529 3.0 69.2 1.0 CG B:HIS467 3.0 79.1 1.0 CB B:CYS524 3.3 76.5 1.0 CB B:HIS529 3.4 68.9 1.0 SD B:MET534 3.5 77.2 1.0 O B:LEU466 3.6 79.0 1.0 NE2 B:HIS467 3.7 81.5 1.0 CB B:HIS467 3.7 76.5 1.0 CA B:HIS467 3.9 75.3 1.0 CD2 B:HIS467 4.0 80.3 1.0 NE2 B:HIS529 4.0 70.7 1.0 CE B:MET534 4.0 72.9 1.0 CB B:LEU526 4.1 72.7 1.0 CD2 B:HIS529 4.1 69.8 1.0 C B:LEU466 4.4 78.7 1.0 CD1 B:LEU526 4.6 73.6 1.0 N B:HIS467 4.6 76.5 1.0 CA B:CYS524 4.6 75.6 1.0 CG B:LEU526 4.9 73.4 1.0 CA B:HIS529 4.9 69.6 1.0

P.Leone, U.Contaldo. Crystal Structure of the Copper Efflux Oxidase (Cueo) From Hafnia Alvei Deleted of the Met-Rich Domain To Be Published.