Copper in PDB 8q1b: III2-IV1 Respiratory Supercomplex From S. Pombe

All present enzymatic activity of III2-IV1 Respiratory Supercomplex From S. Pombe:
7.1.1.9;

The structure of III2-IV1 Respiratory Supercomplex From S. Pombe also contains other interesting chemical elements:

Zinc	(Zn)	3 atoms
Calcium	(Ca)	1 atom
Iron	(Fe)	12 atoms
Magnesium	(Mg)	1 atom

The binding sites of Copper atom in the III2-IV1 Respiratory Supercomplex From S. Pombe (pdb code 8q1b). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 3 binding sites of Copper where determined in the III2-IV1 Respiratory Supercomplex From S. Pombe, PDB code: 8q1b:
Jump to Copper binding site number: 1; 2; 3;

Copper binding site 1 out of 3 in the III2-IV1 Respiratory Supercomplex From S. Pombe


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of III2-IV1 Respiratory Supercomplex From S. Pombe within 5.0Å range: probe atom residue distance (Å) B Occ a:Cu603 b:284.4 occ:1.00 NE2 a:HIS296 1.7 198.4 1.0 ND1 a:HIS247 2.1 204.9 1.0 NE2 a:HIS297 2.4 199.6 1.0 CE1 a:HIS296 2.4 198.4 1.0 CE1 a:HIS297 2.4 196.7 1.0 CD2 a:HIS296 2.9 196.5 1.0 CE1 a:HIS247 3.0 204.4 1.0 CG a:HIS247 3.1 203.5 1.0 CB a:HIS247 3.5 203.6 1.0 CD2 a:HIS297 3.6 198.6 1.0 ND1 a:HIS296 3.6 196.4 1.0 ND1 a:HIS297 3.7 195.9 1.0 CA a:HIS247 3.7 203.2 1.0 CG a:HIS296 3.9 196.0 1.0 NE2 a:HIS247 4.2 204.0 1.0 NA a:HEA602 4.2 160.6 1.0 CD2 a:HIS247 4.2 202.6 1.0 CG a:HIS297 4.2 197.5 1.0 C1A a:HEA602 4.3 159.2 1.0 C4A a:HEA602 4.5 160.6 1.0 O a:HIS247 4.6 201.6 1.0 CHA a:HEA602 4.7 157.7 1.0 FE a:HEA602 4.7 163.2 1.0 ND a:HEA602 4.7 159.7 1.0 C a:HIS247 4.7 202.6 1.0 N a:HIS247 4.7 203.6 1.0 C4D a:HEA602 4.7 157.4 1.0 C2A a:HEA602 4.7 158.2 1.0 C3A a:HEA602 4.8 158.2 1.0

Copper binding site 2 out of 3 in the III2-IV1 Respiratory Supercomplex From S. Pombe


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of III2-IV1 Respiratory Supercomplex From S. Pombe within 5.0Å range: probe atom residue distance (Å) B Occ b:Cu303 b:209.1 occ:1.00 CU1 b:CUA303 0.0 209.1 1.0 ND1 b:HIS225 1.7 168.5 1.0 O b:GLU219 2.1 165.8 1.0 CE1 b:HIS225 2.3 168.1 1.0 CU2 b:CUA303 2.5 214.2 1.0 SG b:CYS221 2.9 173.1 1.0 CG b:HIS225 2.9 166.7 1.0 C b:GLU219 3.1 162.6 1.0 SG b:CYS217 3.3 179.8 1.0 N b:CYS221 3.4 173.6 1.0 NE2 b:HIS225 3.4 166.6 1.0 CB b:CYS221 3.5 171.9 1.0 C b:LEU220 3.6 164.2 1.0 CA b:LEU220 3.6 163.2 1.0 CB b:HIS225 3.6 166.7 1.0 CD2 b:HIS225 3.7 165.9 1.0 N b:LEU220 3.8 160.9 1.0 CA b:CYS221 4.0 172.2 1.0 CB b:CYS217 4.1 174.3 1.0 CA b:HIS225 4.1 165.6 1.0 ND1 b:HIS182 4.1 191.7 1.0 O b:HIS225 4.1 167.2 1.0 N b:GLU219 4.2 165.5 1.0 CA b:GLU219 4.3 163.4 1.0 CE b:MET228 4.4 161.1 1.0 O b:LEU220 4.4 163.6 1.0 C b:HIS225 4.6 165.8 1.0 C b:SER218 4.6 175.5 1.0 N b:SER218 4.9 175.7 1.0 O b:ILE181 4.9 192.8 1.0 CA b:HIS182 4.9 189.2 1.0 CE1 b:HIS182 4.9 190.3 1.0 O b:SER218 5.0 175.8 1.0

Copper binding site 3 out of 3 in the III2-IV1 Respiratory Supercomplex From S. Pombe


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 3 of III2-IV1 Respiratory Supercomplex From S. Pombe within 5.0Å range: probe atom residue distance (Å) B Occ b:Cu303 b:214.2 occ:1.00 CU2 b:CUA303 0.0 214.2 1.0 CE b:MET228 2.4 161.1 1.0 CU1 b:CUA303 2.5 209.1 1.0 ND1 b:HIS182 2.6 191.7 1.0 SG b:CYS221 2.7 173.1 1.0 SD b:MET228 2.8 157.7 1.0 SG b:CYS217 3.4 179.8 1.0 CE1 b:HIS182 3.4 190.3 1.0 ND1 b:HIS225 3.5 168.5 1.0 CB b:CYS217 3.6 174.3 1.0 CG b:HIS182 3.6 190.8 1.0 CB b:CYS221 3.8 171.9 1.0 CB b:HIS182 4.0 188.6 1.0 CG b:MET228 4.0 161.3 1.0 CE1 b:HIS225 4.1 168.1 1.0 O b:GLU219 4.2 165.8 1.0 O b:HIS225 4.3 167.2 1.0 CA b:HIS182 4.5 189.2 1.0 NE2 b:HIS182 4.5 190.2 1.0 CD2 b:HIS182 4.6 190.8 1.0 CA b:HIS225 4.7 165.6 1.0 CG b:HIS225 4.7 166.7 1.0 CZ2 b:TRP122 4.7 185.3 1.0 C b:HIS225 5.0 165.8 1.0

A.Moe, A.R.Dimogkioka, D.Rapaport, L.N.Ojemyr, P.Brzezinski. Structure and Function of the S. Pombe III-IV-Cyt C Supercomplex. Proc.Natl.Acad.Sci.Usa V. 120 97120 2023.
ISSN: ESSN 1091-6490
PubMed: 37939086
DOI: 10.1073/PNAS.2307697120