Copper in PDB 8e7s: III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6
Enzymatic activity of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6
All present enzymatic activity of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6:
7.1.1.8;
7.1.1.9;
Other elements in 8e7s:
The structure of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 also contains other interesting chemical elements:
Copper Binding Sites:
The binding sites of Copper atom in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6
(pdb code 8e7s). This binding sites where shown within
5.0 Angstroms radius around Copper atom.
In total 6 binding sites of Copper where determined in the
III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6, PDB code: 8e7s:
Jump to Copper binding site number:
1;
2;
3;
4;
5;
6;
Copper binding site 1 out
of 6 in 8e7s
Go back to
Copper Binding Sites List in 8e7s
Copper binding site 1 out
of 6 in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6
Mono view
Stereo pair view
|
A full contact list of Copper with other atoms in the Cu binding
site number 1 of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
K:Cu602
b:253.9
occ:1.00
|
NE2
|
K:HIS291
|
2.0
|
253.5
|
1.0
|
NE2
|
K:HIS290
|
2.0
|
254.3
|
1.0
|
ND1
|
K:HIS241
|
2.0
|
254.7
|
1.0
|
CE1
|
K:HIS290
|
2.1
|
254.3
|
1.0
|
CE1
|
K:HIS291
|
2.2
|
253.5
|
1.0
|
CE1
|
K:HIS241
|
2.4
|
254.7
|
1.0
|
CD2
|
K:HIS291
|
3.0
|
253.5
|
1.0
|
ND1
|
K:HIS291
|
3.2
|
253.5
|
1.0
|
CG
|
K:HIS241
|
3.3
|
254.7
|
1.0
|
ND1
|
K:HIS290
|
3.4
|
254.3
|
1.0
|
CD2
|
K:HIS290
|
3.4
|
254.3
|
1.0
|
CG
|
K:HIS291
|
3.6
|
253.5
|
1.0
|
NE2
|
K:HIS241
|
3.6
|
254.7
|
1.0
|
CG
|
K:HIS290
|
4.0
|
254.3
|
1.0
|
CD2
|
K:HIS241
|
4.1
|
254.7
|
1.0
|
CB
|
K:HIS241
|
4.2
|
254.7
|
1.0
|
NA
|
K:HEA601
|
4.4
|
196.6
|
1.0
|
C4A
|
K:HEA601
|
4.4
|
196.6
|
1.0
|
C1A
|
K:HEA601
|
4.5
|
196.6
|
1.0
|
C3A
|
K:HEA601
|
4.6
|
196.6
|
1.0
|
C2A
|
K:HEA601
|
4.7
|
196.6
|
1.0
|
CA
|
K:HIS241
|
4.7
|
254.7
|
1.0
|
CHB
|
K:HEA601
|
4.9
|
196.6
|
1.0
|
OMA
|
K:HEA601
|
4.9
|
196.6
|
1.0
|
CB
|
K:HIS291
|
5.0
|
253.5
|
1.0
|
|
Copper binding site 2 out
of 6 in 8e7s
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Copper Binding Sites List in 8e7s
Copper binding site 2 out
of 6 in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6
Mono view
Stereo pair view
|
A full contact list of Copper with other atoms in the Cu binding
site number 2 of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
P:Cu301
b:245.3
occ:1.00
|
CE1
|
P:HIS229
|
1.8
|
196.5
|
1.0
|
ND1
|
P:HIS229
|
2.0
|
196.5
|
1.0
|
CE
|
P:MET232
|
2.5
|
194.3
|
1.0
|
SG
|
P:CYS225
|
2.6
|
191.9
|
1.0
|
CU2
|
P:CUA302
|
2.7
|
228.1
|
1.0
|
SD
|
P:MET232
|
2.8
|
194.3
|
1.0
|
CE1
|
P:HIS186
|
2.8
|
196.9
|
1.0
|
CG
|
P:MET232
|
2.9
|
194.3
|
1.0
|
ND1
|
P:HIS186
|
3.0
|
196.9
|
1.0
|
NE2
|
P:HIS229
|
3.1
|
196.5
|
1.0
|
CG
|
P:HIS229
|
3.4
|
196.5
|
1.0
|
CB
|
P:CYS225
|
3.6
|
191.9
|
1.0
|
CB
|
P:MET232
|
3.8
|
194.3
|
1.0
|
CD2
|
P:HIS229
|
3.8
|
196.5
|
1.0
|
CB
|
P:CYS221
|
3.8
|
216.1
|
1.0
|
SG
|
P:CYS221
|
4.1
|
216.1
|
1.0
|
NE2
|
P:HIS186
|
4.1
|
196.9
|
1.0
|
CG
|
P:HIS186
|
4.4
|
196.9
|
1.0
|
CB
|
P:HIS229
|
4.5
|
196.5
|
1.0
|
O
|
P:GLU223
|
4.6
|
205.7
|
1.0
|
CA
|
P:HIS229
|
4.7
|
196.5
|
1.0
|
CA
|
P:TRP124
|
4.7
|
166.2
|
1.0
|
NE1
|
P:TRP126
|
4.8
|
178.3
|
1.0
|
CA
|
P:MET232
|
4.9
|
194.3
|
1.0
|
CD2
|
P:HIS186
|
4.9
|
196.9
|
1.0
|
CA
|
P:CYS225
|
4.9
|
191.9
|
1.0
|
|
Copper binding site 3 out
of 6 in 8e7s
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Copper Binding Sites List in 8e7s
Copper binding site 3 out
of 6 in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6
Mono view
Stereo pair view
|
A full contact list of Copper with other atoms in the Cu binding
site number 3 of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
P:Cu302
b:228.1
occ:1.00
|
SG
|
P:CYS225
|
2.0
|
191.9
|
1.0
|
ND1
|
P:HIS186
|
2.0
|
196.9
|
1.0
|
SG
|
P:CYS221
|
2.3
|
216.1
|
1.0
|
CE1
|
P:HIS229
|
2.4
|
196.5
|
1.0
|
CU1
|
P:CUA301
|
2.7
|
245.3
|
1.0
|
CE1
|
P:HIS186
|
2.8
|
196.9
|
1.0
|
CG
|
P:HIS186
|
2.9
|
196.9
|
1.0
|
O
|
P:GLU223
|
3.0
|
205.7
|
1.0
|
NE2
|
P:HIS229
|
3.1
|
196.5
|
1.0
|
CB
|
P:CYS221
|
3.3
|
216.1
|
1.0
|
ND1
|
P:HIS229
|
3.3
|
196.5
|
1.0
|
CB
|
P:HIS186
|
3.4
|
196.9
|
1.0
|
CA
|
P:HIS186
|
3.5
|
196.9
|
1.0
|
NE2
|
P:HIS186
|
3.7
|
196.9
|
1.0
|
CB
|
P:CYS225
|
3.7
|
191.9
|
1.0
|
CD2
|
P:HIS186
|
3.8
|
196.9
|
1.0
|
N
|
P:ASP187
|
4.0
|
207.8
|
1.0
|
C
|
P:GLU223
|
4.1
|
205.7
|
1.0
|
CD2
|
P:HIS229
|
4.2
|
196.5
|
1.0
|
C
|
P:HIS186
|
4.3
|
196.9
|
1.0
|
O
|
P:ILE185
|
4.3
|
197.6
|
1.0
|
CG
|
P:HIS229
|
4.3
|
196.5
|
1.0
|
CB
|
P:GLU223
|
4.4
|
205.7
|
1.0
|
CA
|
P:CYS225
|
4.6
|
191.9
|
1.0
|
N
|
P:CYS225
|
4.6
|
191.9
|
1.0
|
N
|
P:HIS186
|
4.6
|
196.9
|
1.0
|
CA
|
P:GLU223
|
4.6
|
205.7
|
1.0
|
CG
|
P:GLU223
|
4.7
|
205.7
|
1.0
|
N
|
P:GLU223
|
4.7
|
205.7
|
1.0
|
CA
|
P:CYS221
|
4.7
|
216.1
|
1.0
|
C
|
P:LEU224
|
4.7
|
199.9
|
1.0
|
CG
|
P:MET232
|
4.8
|
194.3
|
1.0
|
O
|
P:LEU224
|
4.9
|
199.9
|
1.0
|
C
|
P:ILE185
|
4.9
|
197.6
|
1.0
|
C
|
P:CYS221
|
4.9
|
216.1
|
1.0
|
O
|
P:CYS221
|
5.0
|
216.1
|
1.0
|
|
Copper binding site 4 out
of 6 in 8e7s
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Copper Binding Sites List in 8e7s
Copper binding site 4 out
of 6 in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6
Mono view
Stereo pair view
|
A full contact list of Copper with other atoms in the Cu binding
site number 4 of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
k:Cu601
b:379.1
occ:1.00
|
CE1
|
k:HIS290
|
1.8
|
324.0
|
1.0
|
NE2
|
k:HIS291
|
2.0
|
335.6
|
1.0
|
NE2
|
k:HIS290
|
2.0
|
324.0
|
1.0
|
ND1
|
k:HIS241
|
2.1
|
340.9
|
1.0
|
CE1
|
k:HIS291
|
2.4
|
335.6
|
1.0
|
CE1
|
k:HIS241
|
2.7
|
340.9
|
1.0
|
CD2
|
k:HIS291
|
2.8
|
335.6
|
1.0
|
CG
|
k:HIS241
|
3.1
|
340.9
|
1.0
|
ND1
|
k:HIS290
|
3.1
|
324.0
|
1.0
|
ND1
|
k:HIS291
|
3.3
|
335.6
|
1.0
|
CD2
|
k:HIS290
|
3.4
|
324.0
|
1.0
|
CG
|
k:HIS291
|
3.5
|
335.6
|
1.0
|
CB
|
k:HIS241
|
3.7
|
340.9
|
1.0
|
NE2
|
k:HIS241
|
3.8
|
340.9
|
1.0
|
CG
|
k:HIS290
|
3.9
|
324.0
|
1.0
|
CD2
|
k:HIS241
|
4.0
|
340.9
|
1.0
|
CA
|
k:HIS241
|
4.4
|
340.9
|
1.0
|
CG2
|
k:VAL287
|
4.8
|
307.8
|
1.0
|
CB
|
k:HIS291
|
4.9
|
335.6
|
1.0
|
O
|
k:VAL287
|
4.9
|
307.8
|
1.0
|
|
Copper binding site 5 out
of 6 in 8e7s
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Copper Binding Sites List in 8e7s
Copper binding site 5 out
of 6 in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6
Mono view
Stereo pair view
|
A full contact list of Copper with other atoms in the Cu binding
site number 5 of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
p:Cu301
b:365.9
occ:1.00
|
CE1
|
p:HIS229
|
1.1
|
325.7
|
1.0
|
ND1
|
p:HIS229
|
2.0
|
325.7
|
1.0
|
NE2
|
p:HIS229
|
2.2
|
325.7
|
1.0
|
SD
|
p:MET232
|
2.3
|
306.7
|
1.0
|
CU2
|
p:CUA302
|
2.7
|
331.0
|
1.0
|
SG
|
p:CYS225
|
2.7
|
318.2
|
1.0
|
CG
|
p:HIS229
|
3.1
|
325.7
|
1.0
|
CD2
|
p:HIS229
|
3.2
|
325.7
|
1.0
|
CB
|
p:CYS221
|
3.4
|
303.8
|
1.0
|
CE
|
p:MET232
|
3.6
|
306.7
|
1.0
|
SG
|
p:CYS221
|
3.6
|
303.8
|
1.0
|
CG
|
p:MET232
|
3.9
|
306.7
|
1.0
|
O
|
p:GLU223
|
3.9
|
321.2
|
1.0
|
CB
|
p:CYS225
|
3.9
|
318.2
|
1.0
|
ND1
|
p:HIS186
|
4.1
|
280.9
|
1.0
|
O
|
p:CYS221
|
4.1
|
303.8
|
1.0
|
CB
|
p:MET232
|
4.2
|
306.7
|
1.0
|
CE1
|
p:HIS186
|
4.4
|
280.9
|
1.0
|
CB
|
p:HIS229
|
4.4
|
325.7
|
1.0
|
CA
|
p:CYS221
|
4.5
|
303.8
|
1.0
|
O
|
p:HIS229
|
4.6
|
325.7
|
1.0
|
C
|
p:CYS221
|
4.7
|
303.8
|
1.0
|
CA
|
p:HIS229
|
4.7
|
325.7
|
1.0
|
N
|
p:CYS225
|
4.8
|
318.2
|
1.0
|
N
|
p:CYS221
|
4.9
|
303.8
|
1.0
|
|
Copper binding site 6 out
of 6 in 8e7s
Go back to
Copper Binding Sites List in 8e7s
Copper binding site 6 out
of 6 in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6
Mono view
Stereo pair view
|
A full contact list of Copper with other atoms in the Cu binding
site number 6 of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
p:Cu302
b:331.0
occ:1.00
|
ND1
|
p:HIS186
|
2.0
|
280.9
|
1.0
|
SG
|
p:CYS225
|
2.1
|
318.2
|
1.0
|
SG
|
p:CYS221
|
2.1
|
303.8
|
1.0
|
CU1
|
p:CUA301
|
2.7
|
365.9
|
1.0
|
CG
|
p:HIS186
|
2.9
|
280.9
|
1.0
|
CE1
|
p:HIS186
|
3.0
|
280.9
|
1.0
|
CE1
|
p:HIS229
|
3.0
|
325.7
|
1.0
|
CB
|
p:CYS221
|
3.2
|
303.8
|
1.0
|
CB
|
p:HIS186
|
3.3
|
280.9
|
1.0
|
O
|
p:GLU223
|
3.4
|
321.2
|
1.0
|
CA
|
p:HIS186
|
3.5
|
280.9
|
1.0
|
NE2
|
p:HIS229
|
3.7
|
325.7
|
1.0
|
CB
|
p:CYS225
|
3.9
|
318.2
|
1.0
|
ND1
|
p:HIS229
|
4.0
|
325.7
|
1.0
|
N
|
p:ASP187
|
4.0
|
279.5
|
1.0
|
NE2
|
p:HIS186
|
4.0
|
280.9
|
1.0
|
CD2
|
p:HIS186
|
4.0
|
280.9
|
1.0
|
C
|
p:HIS186
|
4.3
|
280.9
|
1.0
|
C
|
p:GLU223
|
4.5
|
321.2
|
1.0
|
CA
|
p:CYS221
|
4.5
|
303.8
|
1.0
|
O
|
p:ILE185
|
4.6
|
272.8
|
1.0
|
O
|
p:CYS221
|
4.7
|
303.8
|
1.0
|
N
|
p:HIS186
|
4.7
|
280.9
|
1.0
|
SD
|
p:MET232
|
4.8
|
306.7
|
1.0
|
CA
|
p:CYS225
|
4.8
|
318.2
|
1.0
|
C
|
p:CYS221
|
4.8
|
303.8
|
1.0
|
CB
|
p:GLU223
|
4.8
|
321.2
|
1.0
|
N
|
p:CYS225
|
4.8
|
318.2
|
1.0
|
CD2
|
p:HIS229
|
4.9
|
325.7
|
1.0
|
N
|
p:GLU223
|
5.0
|
321.2
|
1.0
|
CZ2
|
p:TRP126
|
5.0
|
275.3
|
1.0
|
C
|
p:LEU224
|
5.0
|
324.4
|
1.0
|
|
Reference:
C.F.Hryc,
V.K.P.S.Mallampalli,
E.I.Bovshik,
S.Azinas,
G.Fan,
I.I.Serysheva,
G.C.Sparagna,
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ISSN: ESSN 2041-1723
PubMed: 37188665
DOI: 10.1038/S41467-023-38441-5
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