Copper in PDB 7z10: Monomeric Respiratory Complex IV Isolated From S. Cerevisiae

All present enzymatic activity of Monomeric Respiratory Complex IV Isolated From S. Cerevisiae:
1.9.3.1; 7.1.1.9;

The structure of Monomeric Respiratory Complex IV Isolated From S. Cerevisiae also contains other interesting chemical elements:

Zinc	(Zn)	1 atom
Iron	(Fe)	2 atoms
Magnesium	(Mg)	1 atom

The binding sites of Copper atom in the Monomeric Respiratory Complex IV Isolated From S. Cerevisiae (pdb code 7z10). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 3 binding sites of Copper where determined in the Monomeric Respiratory Complex IV Isolated From S. Cerevisiae, PDB code: 7z10:
Jump to Copper binding site number: 1; 2; 3;

Copper binding site 1 out of 3 in the Monomeric Respiratory Complex IV Isolated From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Monomeric Respiratory Complex IV Isolated From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ a:Cu601 b:167.7 occ:1.00 ND1 a:HIS241 2.0 153.2 1.0 NE2 a:HIS291 2.0 164.6 1.0 NE2 a:HIS290 2.2 166.1 1.0 CG a:HIS241 2.3 153.2 1.0 CB a:HIS241 2.4 153.2 1.0 CE1 a:HIS290 2.6 166.1 1.0 CE1 a:HIS291 2.8 164.6 1.0 CE1 a:HIS241 3.1 153.2 1.0 CD2 a:HIS291 3.2 164.6 1.0 CA a:HIS241 3.3 153.2 1.0 CD2 a:HIS290 3.5 166.1 1.0 CD2 a:HIS241 3.5 153.2 1.0 ND1 a:HIS290 3.9 166.1 1.0 NE2 a:HIS241 3.9 153.2 1.0 ND1 a:HIS291 3.9 164.6 1.0 N a:HIS241 4.1 153.2 1.0 CG a:HIS291 4.1 164.6 1.0 CG a:HIS290 4.3 166.1 1.0 CG2 a:VAL244 4.4 144.5 1.0 C a:HIS241 4.5 153.2 1.0 O a:HIS241 4.7 153.2 1.0 C a:GLY240 4.9 155.6 1.0 CE2 a:TYR245 4.9 148.4 1.0 ND a:HEA603 4.9 153.7 1.0

Copper binding site 2 out of 3 in the Monomeric Respiratory Complex IV Isolated From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Monomeric Respiratory Complex IV Isolated From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ b:Cu301 b:206.6 occ:1.00 CU1 b:CUA301 0.0 206.6 1.0 ND1 b:HIS229 2.2 177.5 1.0 SG b:CYS225 2.3 187.7 1.0 SG b:CYS221 2.3 185.0 1.0 O b:GLU223 2.4 176.8 1.0 CU2 b:CUA301 2.6 218.2 1.0 CB b:CYS221 3.0 185.0 1.0 CB b:CYS225 3.1 187.7 1.0 O b:CYS221 3.1 185.0 1.0 CE1 b:HIS229 3.2 177.5 1.0 CG b:HIS229 3.2 177.5 1.0 O b:HIS229 3.3 177.5 1.0 CA b:HIS229 3.5 177.5 1.0 CB b:HIS229 3.5 177.5 1.0 C b:GLU223 3.6 176.8 1.0 C b:CYS221 3.7 185.0 1.0 C b:HIS229 3.8 177.5 1.0 N b:CYS225 3.9 187.7 1.0 CA b:CYS221 4.0 185.0 1.0 CA b:CYS225 4.1 187.7 1.0 C b:LEU224 4.1 176.6 1.0 N b:GLU223 4.1 176.8 1.0 ND1 b:HIS186 4.2 187.2 1.0 NE2 b:HIS229 4.3 177.5 1.0 CD2 b:HIS229 4.3 177.5 1.0 CA b:LEU224 4.5 176.6 1.0 CA b:GLU223 4.5 176.8 1.0 N b:LEU224 4.5 176.6 1.0 SD b:MET232 4.6 184.2 1.0 O b:LEU224 4.6 176.6 1.0 CE1 b:HIS186 4.6 187.2 1.0 N b:SER222 4.8 178.1 1.0 O b:GLY228 4.8 181.2 1.0 N b:HIS229 4.8 177.5 1.0 N b:CYS221 4.8 185.0 1.0

Copper binding site 3 out of 3 in the Monomeric Respiratory Complex IV Isolated From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 3 of Monomeric Respiratory Complex IV Isolated From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ b:Cu301 b:218.2 occ:1.00 CU2 b:CUA301 0.0 218.2 1.0 ND1 b:HIS186 2.1 187.2 1.0 SG b:CYS225 2.2 187.7 1.0 SG b:CYS221 2.2 185.0 1.0 SD b:MET232 2.3 184.2 1.0 CE1 b:HIS186 2.5 187.2 1.0 CU1 b:CUA301 2.6 206.6 1.0 CB b:CYS221 2.6 185.0 1.0 CB b:CYS225 3.2 187.7 1.0 CG b:HIS186 3.5 187.2 1.0 CE b:MET232 3.6 184.2 1.0 NE2 b:HIS186 3.8 187.2 1.0 CG b:MET232 3.9 184.2 1.0 CA b:CYS221 4.1 185.0 1.0 CB b:MET232 4.2 184.2 1.0 CD2 b:HIS186 4.2 187.2 1.0 CB b:HIS186 4.2 187.2 1.0 O b:GLY228 4.4 181.2 1.0 O b:HIS229 4.6 177.5 1.0 O b:GLU223 4.6 176.8 1.0 CA b:CYS225 4.6 187.7 1.0 CA b:HIS229 4.7 177.5 1.0 O b:CYS221 4.8 185.0 1.0 C b:CYS221 4.8 185.0 1.0 CA b:HIS186 4.8 187.2 1.0 ND1 b:HIS229 4.8 177.5 1.0 N b:CYS221 5.0 185.0 1.0

G.Ing, A.M.Hartley, N.Pinotsis, A.Marechal. Cryo-Em Structure of A Monomeric Yeast S. Cerevisiae Complex IV Isolated with Maltosides: Implications in Supercomplex Formation. Biochim Biophys Acta V.1863 48591 2022BIOENERG.
ISSN: ISSN 1879-2650
PubMed: 35839926
DOI: 10.1016/J.BBABIO.2022.148591