Copper in PDB 7ysu: Cryo-Em Structure of FGF23-FGFR3C-Aklotho-Hs Quaternary Complex

All present enzymatic activity of Cryo-Em Structure of FGF23-FGFR3C-Aklotho-Hs Quaternary Complex:
2.7.10.1; 3.2.1.31;

The structure of Cryo-Em Structure of FGF23-FGFR3C-Aklotho-Hs Quaternary Complex also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Copper atom in the Cryo-Em Structure of FGF23-FGFR3C-Aklotho-Hs Quaternary Complex (pdb code 7ysu). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total only one binding site of Copper was determined in the Cryo-Em Structure of FGF23-FGFR3C-Aklotho-Hs Quaternary Complex, PDB code: 7ysu:

Copper binding site 1 out of 1 in the Cryo-Em Structure of FGF23-FGFR3C-Aklotho-Hs Quaternary Complex


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Cryo-Em Structure of FGF23-FGFR3C-Aklotho-Hs Quaternary Complex within 5.0Å range: probe atom residue distance (Å) B Occ E:Cu401 b:183.3 occ:1.00 OD1 E:ASP282 2.1 184.3 1.0 NE2 E:HIS253 2.1 146.2 1.0 CE1 C:HIS253 2.6 146.5 1.0 CD2 E:HIS253 2.7 145.7 1.0 NE2 C:HIS253 2.8 145.5 1.0 CG E:ASP282 3.1 183.1 1.0 CE1 E:HIS253 3.4 144.8 1.0 ND1 C:HIS253 3.4 145.8 1.0 OD2 E:ASP282 3.5 183.9 1.0 CD2 C:HIS253 3.8 142.4 1.0 CG E:HIS253 4.0 146.3 1.0 CG C:HIS253 4.1 142.2 1.0 CD C:PRO252 4.2 136.4 1.0 ND1 E:HIS253 4.3 146.7 1.0 CB E:ASP282 4.4 183.1 1.0 CB E:SER251 4.5 146.8 1.0 N C:PRO252 4.7 134.8 1.0 O C:PRO252 4.8 141.3 1.0 CG C:PRO252 4.8 138.6 1.0 N E:ASP282 4.9 186.0 1.0 CA C:SER251 4.9 130.3 1.0 CD E:PRO252 4.9 126.8 1.0

L.Chen, M.Mohammadi. Fgf Hormones Signal Via Dual Co-Receptor Dependent Asymmetric Fgf Receptor Dimers To Be Published.