Copper in PDB 7ysh: Cryo-Em Structure of FGF23-FGFR1C-Aklotho-Hs Quaternary Complex

All present enzymatic activity of Cryo-Em Structure of FGF23-FGFR1C-Aklotho-Hs Quaternary Complex:
2.7.10.1; 3.2.1.31;

The structure of Cryo-Em Structure of FGF23-FGFR1C-Aklotho-Hs Quaternary Complex also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Copper atom in the Cryo-Em Structure of FGF23-FGFR1C-Aklotho-Hs Quaternary Complex (pdb code 7ysh). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total only one binding site of Copper was determined in the Cryo-Em Structure of FGF23-FGFR1C-Aklotho-Hs Quaternary Complex, PDB code: 7ysh:

Copper binding site 1 out of 1 in the Cryo-Em Structure of FGF23-FGFR1C-Aklotho-Hs Quaternary Complex


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Cryo-Em Structure of FGF23-FGFR1C-Aklotho-Hs Quaternary Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Cu401 b:103.0 occ:1.00 NE2 D:HIS253 2.2 66.1 1.0 NE2 E:HIS253 2.2 84.4 1.0 CE1 D:HIS253 2.6 66.1 1.0 CE1 E:HIS253 3.0 84.4 1.0 CD2 E:HIS253 3.3 84.4 1.0 CD2 D:HIS253 3.4 66.1 1.0 CB E:SER251 3.6 88.5 1.0 ND1 D:HIS253 3.8 66.1 1.0 ND1 E:HIS253 4.2 84.4 1.0 CG D:HIS253 4.2 66.1 1.0 CG E:HIS253 4.3 84.4 1.0 CA E:SER251 4.4 88.5 1.0 CD D:PRO252 4.6 63.0 1.0 OG E:SER251 4.7 88.5 1.0 CD E:PRO252 4.7 80.4 1.0 N E:ASP282 4.8 106.8 1.0

L.Chen, M.Mohammadi. Fgf Hormones Signal Via Dual Co-Receptor Dependent Asymmetric Fgf Receptor Dimers To Be Published.