Copper in PDB 7wx0: E40K Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris)

All present enzymatic activity of E40K Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris):
1.15.1.1;

The structure of E40K Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris), PDB code: 7wx0 was solved by S.Narikiyo, Y.Furukawa, M.Akutsu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.94 / 1.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	38.781, 50.677, 185.905, 90, 90, 90
R / Rfree (%)	17.1 / 19.1

The structure of E40K Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris) also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Copper atom in the E40K Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris) (pdb code 7wx0). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 2 binding sites of Copper where determined in the E40K Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris), PDB code: 7wx0:
Jump to Copper binding site number: 1; 2;

Copper binding site 1 out of 2 in the E40K Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris)


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of E40K Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu202 b:20.6 occ:1.00 ND1 A:HIS46 2.0 18.4 1.0 NE2 A:HIS48 2.0 17.4 1.0 NE2 A:HIS120 2.0 15.7 1.0 CG A:HIS46 3.0 17.6 1.0 CE1 A:HIS48 3.0 17.8 1.0 CD2 A:HIS120 3.0 18.4 1.0 CE1 A:HIS46 3.0 17.4 1.0 CD2 A:HIS48 3.0 16.5 1.0 CE1 A:HIS120 3.1 18.8 1.0 NE2 A:HIS63 3.2 20.6 1.0 CB A:HIS46 3.3 18.7 1.0 O A:HOH370 3.5 27.0 1.0 CD2 A:HIS63 3.6 20.8 1.0 CB A:VAL118 4.0 15.5 1.0 CD2 A:HIS46 4.1 18.8 1.0 NE2 A:HIS46 4.1 18.4 1.0 ND1 A:HIS48 4.1 17.8 1.0 CG A:HIS120 4.1 17.9 1.0 CG A:HIS48 4.1 16.3 1.0 CE1 A:HIS63 4.1 21.4 1.0 ND1 A:HIS120 4.2 16.9 1.0 CG1 A:VAL118 4.2 18.1 1.0 N A:HIS46 4.2 16.3 1.0 CA A:HIS46 4.2 17.0 1.0 O A:VAL118 4.4 16.9 1.0 O A:HIS46 4.5 16.4 1.0 CG A:HIS63 4.6 18.8 1.0 C A:HIS46 4.7 17.8 1.0 CG2 A:VAL118 4.7 17.2 1.0 ND1 A:HIS63 4.9 18.4 1.0 C A:VAL118 5.0 15.3 1.0 CA A:VAL118 5.0 15.4 1.0

Copper binding site 2 out of 2 in the E40K Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris)


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of E40K Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cu202 b:17.3 occ:1.00 NE2 B:HIS48 1.9 13.5 1.0 NE2 B:HIS120 2.0 13.8 1.0 ND1 B:HIS46 2.0 13.4 1.0 CE1 B:HIS48 2.9 13.7 1.0 CD2 B:HIS120 2.9 16.0 1.0 CD2 B:HIS48 3.0 13.2 1.0 CE1 B:HIS46 3.0 14.3 1.0 CG B:HIS46 3.0 12.7 1.0 CE1 B:HIS120 3.0 14.6 1.0 NE2 B:HIS63 3.2 14.8 1.0 CB B:HIS46 3.3 15.1 1.0 CD2 B:HIS63 3.6 16.1 1.0 O B:HOH397 3.6 20.9 1.0 CB B:VAL118 3.9 13.3 1.0 ND1 B:HIS48 4.0 14.2 1.0 CG B:HIS48 4.1 13.4 1.0 CG1 B:VAL118 4.1 15.3 1.0 CG B:HIS120 4.1 15.2 1.0 ND1 B:HIS120 4.1 15.1 1.0 NE2 B:HIS46 4.1 14.4 1.0 N B:HIS46 4.1 13.0 1.0 CD2 B:HIS46 4.2 14.4 1.0 CE1 B:HIS63 4.2 14.5 1.0 CA B:HIS46 4.2 13.5 1.0 O B:VAL118 4.5 14.0 1.0 O B:HIS46 4.5 13.8 1.0 C B:HIS46 4.6 12.9 1.0 CG B:HIS63 4.7 14.1 1.0 CG2 B:VAL118 4.7 14.8 1.0 ND1 B:HIS63 4.9 13.8 1.0 C B:VAL118 5.0 13.2 1.0 CA B:VAL118 5.0 13.2 1.0

S.Narikiyo, Y.Furukawa, M.Akutsu. Crystal Structure of Dog Superoxide Dismutase To Be Published.