Copper in PDB 7rh7: Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound
Enzymatic activity of Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound
All present enzymatic activity of Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound:
1.15.1.1;
7.1.1.8;
7.1.1.9;
Other elements in 7rh7:
The structure of Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound also contains other interesting chemical elements:
Copper Binding Sites:
The binding sites of Copper atom in the Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound
(pdb code 7rh7). This binding sites where shown within
5.0 Angstroms radius around Copper atom.
In total 6 binding sites of Copper where determined in the
Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound, PDB code: 7rh7:
Jump to Copper binding site number:
1;
2;
3;
4;
5;
6;
Copper binding site 1 out
of 6 in 7rh7
Go back to
Copper Binding Sites List in 7rh7
Copper binding site 1 out
of 6 in the Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound
 Mono view
 Stereo pair view
|
|
A full contact list of Copper with other atoms in the Cu binding
site number 1 of Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
Q:Cu401
b:52.1
occ:1.00
|
HG
|
Q:CYS277
|
1.6
|
42.0
|
1.0
|
|
HE1
|
Q:HIS281
|
1.6
|
42.5
|
1.0
|
|
HD1
|
Q:HIS281
|
1.7
|
42.5
|
1.0
|
|
SG
|
Q:CYS277
|
1.7
|
42.0
|
1.0
|
|
SG
|
Q:CYS273
|
1.9
|
42.2
|
1.0
|
|
CE1
|
Q:HIS281
|
1.9
|
42.5
|
1.0
|
|
ND1
|
Q:HIS281
|
2.0
|
42.5
|
1.0
|
|
HB3
|
Q:CYS273
|
2.7
|
42.2
|
1.0
|
|
CB
|
Q:CYS273
|
2.9
|
42.2
|
1.0
|
|
HG
|
Q:CYS273
|
2.9
|
42.2
|
1.0
|
|
HB2
|
Q:HIS232
|
3.0
|
42.7
|
1.0
|
|
NE2
|
Q:HIS281
|
3.2
|
42.5
|
1.0
|
|
CB
|
Q:CYS277
|
3.3
|
42.0
|
1.0
|
|
HB2
|
Q:CYS277
|
3.4
|
42.0
|
1.0
|
|
CG
|
Q:HIS281
|
3.4
|
42.5
|
1.0
|
|
HB2
|
Q:CYS273
|
3.4
|
42.2
|
1.0
|
|
SD
|
Q:MET284
|
3.6
|
43.8
|
1.0
|
|
H
|
Q:GLU275
|
3.6
|
41.0
|
1.0
|
|
HB3
|
Q:HIS232
|
3.7
|
42.7
|
1.0
|
|
CB
|
Q:HIS232
|
3.7
|
42.7
|
1.0
|
|
HE3
|
Q:MET284
|
3.8
|
43.8
|
1.0
|
|
HE2
|
Q:HIS281
|
3.8
|
42.5
|
1.0
|
|
HB3
|
Q:MET284
|
3.8
|
43.8
|
1.0
|
|
HB3
|
Q:CYS277
|
3.9
|
42.0
|
1.0
|
|
H
|
Q:GLY233
|
3.9
|
41.6
|
1.0
|
|
CD2
|
Q:HIS281
|
3.9
|
42.5
|
1.0
|
|
HA
|
Q:HIS281
|
3.9
|
42.5
|
1.0
|
|
CA
|
Q:CYS273
|
4.0
|
42.2
|
1.0
|
|
C
|
Q:CYS273
|
4.0
|
42.2
|
1.0
|
|
CE
|
Q:MET284
|
4.1
|
43.8
|
1.0
|
|
HB3
|
Q:GLU275
|
4.1
|
41.0
|
1.0
|
|
HE2
|
Q:MET284
|
4.1
|
43.8
|
1.0
|
|
H
|
Q:CYS277
|
4.1
|
42.0
|
1.0
|
|
N
|
Q:CYS277
|
4.2
|
42.0
|
1.0
|
|
O
|
Q:HIS281
|
4.2
|
42.5
|
1.0
|
|
O
|
Q:CYS273
|
4.3
|
42.2
|
1.0
|
|
CA
|
Q:CYS277
|
4.3
|
42.0
|
1.0
|
|
HD2
|
Q:HIS232
|
4.3
|
42.7
|
1.0
|
|
O
|
Q:GLU275
|
4.3
|
41.0
|
1.0
|
|
N
|
Q:GLU275
|
4.4
|
41.0
|
1.0
|
|
CG
|
Q:HIS232
|
4.4
|
42.7
|
1.0
|
|
CB
|
Q:HIS281
|
4.4
|
42.5
|
1.0
|
|
HB2
|
Q:MET284
|
4.4
|
43.8
|
1.0
|
|
CB
|
Q:MET284
|
4.4
|
43.8
|
1.0
|
|
HA
|
Q:CYS273
|
4.5
|
42.2
|
1.0
|
|
N
|
Q:THR274
|
4.5
|
41.8
|
1.0
|
|
H
|
Q:THR274
|
4.5
|
41.8
|
1.0
|
|
C
|
Q:GLU275
|
4.5
|
41.0
|
1.0
|
|
HB2
|
Q:HIS281
|
4.5
|
42.5
|
1.0
|
|
HA
|
Q:CYS277
|
4.5
|
42.0
|
1.0
|
|
CA
|
Q:HIS281
|
4.5
|
42.5
|
1.0
|
|
CD2
|
Q:HIS232
|
4.6
|
42.7
|
1.0
|
|
CG
|
Q:MET284
|
4.6
|
43.8
|
1.0
|
|
CU
|
Q:CU402
|
4.6
|
52.9
|
1.0
|
|
C
|
Q:MET276
|
4.7
|
39.8
|
1.0
|
|
N
|
Q:GLY233
|
4.7
|
41.6
|
1.0
|
|
C
|
Q:HIS281
|
4.8
|
42.5
|
1.0
|
|
CA
|
Q:GLU275
|
4.8
|
41.0
|
1.0
|
|
HD2
|
Q:HIS281
|
4.9
|
42.5
|
1.0
|
|
CB
|
Q:GLU275
|
4.9
|
41.0
|
1.0
|
|
HA
|
Q:HIS232
|
4.9
|
42.7
|
1.0
|
|
CA
|
Q:HIS232
|
4.9
|
42.7
|
1.0
|
|
HG2
|
Q:MET284
|
4.9
|
43.8
|
1.0
|
|
HA
|
Q:MET276
|
4.9
|
39.8
|
1.0
|
|
Copper binding site 2 out
of 6 in 7rh7
Go back to
Copper Binding Sites List in 7rh7
Copper binding site 2 out
of 6 in the Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound
 Mono view
 Stereo pair view
|
|
A full contact list of Copper with other atoms in the Cu binding
site number 2 of Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
Q:Cu402
b:52.9
occ:1.00
|
HE2
|
Q:MET284
|
1.7
|
43.8
|
1.0
|
|
CE1
|
Q:HIS232
|
1.9
|
42.7
|
1.0
|
|
ND1
|
Q:HIS232
|
2.0
|
42.7
|
1.0
|
|
NE2
|
Q:HIS232
|
2.0
|
42.7
|
1.0
|
|
CD2
|
Q:HIS232
|
2.2
|
42.7
|
1.0
|
|
CG
|
Q:HIS232
|
2.2
|
42.7
|
1.0
|
|
HE1
|
Q:HIS232
|
2.5
|
42.7
|
1.0
|
|
HD1
|
Q:HIS232
|
2.5
|
42.7
|
1.0
|
|
CE
|
Q:MET284
|
2.7
|
43.8
|
1.0
|
|
HD2
|
Q:HIS232
|
2.8
|
42.7
|
1.0
|
|
HE1
|
Q:MET284
|
3.1
|
43.8
|
1.0
|
|
HE3
|
Q:MET284
|
3.3
|
43.8
|
1.0
|
|
CB
|
Q:HIS232
|
3.3
|
42.7
|
1.0
|
|
HB3
|
Q:HIS232
|
3.3
|
42.7
|
1.0
|
|
SD
|
Q:MET284
|
3.4
|
43.8
|
1.0
|
|
HG
|
Q:CYS277
|
3.4
|
42.0
|
1.0
|
|
H
|
Q:TRP138
|
3.5
|
45.0
|
1.0
|
|
SG
|
Q:CYS277
|
3.5
|
42.0
|
1.0
|
|
HB2
|
Q:HIS232
|
3.6
|
42.7
|
1.0
|
|
HB3
|
Q:CYS277
|
3.6
|
42.0
|
1.0
|
|
O
|
Q:PHE136
|
3.7
|
46.6
|
1.0
|
|
HG11
|
Q:VAL230
|
3.7
|
42.9
|
1.0
|
|
HG13
|
Q:VAL230
|
3.8
|
42.9
|
1.0
|
|
HA
|
Q:GLN137
|
3.8
|
45.1
|
1.0
|
|
O
|
Q:ALA135
|
4.0
|
44.2
|
1.0
|
|
CB
|
Q:CYS277
|
4.1
|
42.0
|
1.0
|
|
CG1
|
Q:VAL230
|
4.1
|
42.9
|
1.0
|
|
HB3
|
Q:ALA135
|
4.2
|
44.2
|
1.0
|
|
C
|
Q:PHE136
|
4.3
|
46.6
|
1.0
|
|
O
|
Q:VAL230
|
4.3
|
42.9
|
1.0
|
|
N
|
Q:TRP138
|
4.3
|
45.0
|
1.0
|
|
HG
|
Q:SER227
|
4.4
|
44.5
|
1.0
|
|
HB2
|
Q:ALA135
|
4.4
|
44.2
|
1.0
|
|
HG12
|
Q:VAL230
|
4.4
|
42.9
|
1.0
|
|
C
|
Q:ALA135
|
4.5
|
44.2
|
1.0
|
|
HG
|
Q:CYS273
|
4.5
|
42.2
|
1.0
|
|
HA
|
Q:CYS277
|
4.6
|
42.0
|
1.0
|
|
CA
|
Q:HIS232
|
4.6
|
42.7
|
1.0
|
|
CA
|
Q:GLN137
|
4.6
|
45.1
|
1.0
|
|
HG23
|
Q:VAL245
|
4.6
|
43.1
|
1.0
|
|
CU
|
Q:CU401
|
4.6
|
52.1
|
1.0
|
|
HE22
|
Q:GLN137
|
4.7
|
45.1
|
1.0
|
|
SG
|
Q:CYS273
|
4.7
|
42.2
|
1.0
|
|
CB
|
Q:ALA135
|
4.7
|
44.2
|
1.0
|
|
HG21
|
Q:VAL245
|
4.8
|
43.1
|
1.0
|
|
O
|
Q:ILE231
|
4.8
|
41.7
|
1.0
|
|
N
|
Q:GLN137
|
4.8
|
45.1
|
1.0
|
|
H
|
Q:VAL230
|
4.8
|
42.9
|
1.0
|
|
N
|
Q:HIS232
|
4.8
|
42.7
|
1.0
|
|
HB2
|
Q:CYS277
|
4.8
|
42.0
|
1.0
|
|
H
|
Q:ASN139
|
4.9
|
44.9
|
1.0
|
|
HA
|
Q:TRP138
|
4.9
|
45.0
|
1.0
|
|
NE2
|
Q:GLN137
|
4.9
|
45.1
|
1.0
|
|
CA
|
Q:CYS277
|
5.0
|
42.0
|
1.0
|
|
N
|
Q:PHE136
|
5.0
|
46.6
|
1.0
|
|
HE21
|
Q:GLN137
|
5.0
|
45.1
|
1.0
|
|
OG
|
Q:SER227
|
5.0
|
44.5
|
1.0
|
|
Copper binding site 3 out
of 6 in 7rh7
Go back to
Copper Binding Sites List in 7rh7
Copper binding site 3 out
of 6 in the Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound
 Mono view
 Stereo pair view
|
|
A full contact list of Copper with other atoms in the Cu binding
site number 3 of Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
R:Cu601
b:69.2
occ:1.00
|
HE1
|
R:HIS313
|
1.5
|
41.8
|
1.0
|
|
CE1
|
R:HIS313
|
1.8
|
41.8
|
1.0
|
|
NE2
|
R:HIS313
|
2.0
|
41.8
|
1.0
|
|
NE2
|
R:HIS314
|
2.0
|
40.4
|
1.0
|
|
ND1
|
R:HIS264
|
2.0
|
39.4
|
1.0
|
|
HE1
|
R:HIS264
|
2.2
|
39.4
|
1.0
|
|
CE1
|
R:HIS264
|
2.4
|
39.4
|
1.0
|
|
CE1
|
R:HIS314
|
2.5
|
40.4
|
1.0
|
|
HE1
|
R:HIS314
|
2.7
|
40.4
|
1.0
|
|
ND1
|
R:HIS313
|
3.0
|
41.8
|
1.0
|
|
CD2
|
R:HIS314
|
3.0
|
40.4
|
1.0
|
|
CD2
|
R:HIS313
|
3.3
|
41.8
|
1.0
|
|
CG
|
R:HIS264
|
3.3
|
39.4
|
1.0
|
|
HD2
|
R:HIS314
|
3.4
|
40.4
|
1.0
|
|
HD1
|
R:HIS313
|
3.5
|
41.8
|
1.0
|
|
NE2
|
R:HIS264
|
3.6
|
39.4
|
1.0
|
|
ND1
|
R:HIS314
|
3.6
|
40.4
|
1.0
|
|
NA
|
R:HEA603
|
3.7
|
44.0
|
1.0
|
|
CG
|
R:HIS313
|
3.7
|
41.8
|
1.0
|
|
HB2
|
R:HIS264
|
3.8
|
39.4
|
1.0
|
|
CG
|
R:HIS314
|
3.9
|
40.4
|
1.0
|
|
HD2
|
R:HIS313
|
3.9
|
41.8
|
1.0
|
|
C4A
|
R:HEA603
|
4.0
|
44.0
|
1.0
|
|
CD2
|
R:HIS264
|
4.0
|
39.4
|
1.0
|
|
C1A
|
R:HEA603
|
4.1
|
44.0
|
1.0
|
|
FE
|
R:HEA603
|
4.1
|
44.0
|
1.0
|
|
CB
|
R:HIS264
|
4.1
|
39.4
|
1.0
|
|
HA
|
R:HIS264
|
4.2
|
39.4
|
1.0
|
|
HE2
|
R:HIS264
|
4.2
|
39.4
|
1.0
|
|
HD1
|
R:HIS314
|
4.3
|
40.4
|
1.0
|
|
HE1
|
R:TYR268
|
4.3
|
38.4
|
1.0
|
|
HG22
|
R:VAL267
|
4.3
|
38.2
|
1.0
|
|
CHB
|
R:HEA603
|
4.4
|
44.0
|
1.0
|
|
NB
|
R:HEA603
|
4.5
|
44.0
|
1.0
|
|
CHA
|
R:HEA603
|
4.5
|
44.0
|
1.0
|
|
C3A
|
R:HEA603
|
4.5
|
44.0
|
1.0
|
|
ND
|
R:HEA603
|
4.5
|
44.0
|
1.0
|
|
C2A
|
R:HEA603
|
4.6
|
44.0
|
1.0
|
|
C1B
|
R:HEA603
|
4.6
|
44.0
|
1.0
|
|
HH
|
R:TYR268
|
4.6
|
38.4
|
1.0
|
|
CA
|
R:HIS264
|
4.7
|
39.4
|
1.0
|
|
C4D
|
R:HEA603
|
4.7
|
44.0
|
1.0
|
|
HG21
|
R:VAL267
|
4.8
|
38.2
|
1.0
|
|
O
|
R:VAL310
|
4.9
|
40.9
|
1.0
|
|
H
|
R:HIS314
|
4.9
|
40.4
|
1.0
|
|
O
|
R:TRP311
|
4.9
|
40.5
|
1.0
|
|
HB3
|
R:HIS264
|
4.9
|
39.4
|
1.0
|
|
HD2
|
R:HIS264
|
5.0
|
39.4
|
1.0
|
|
Copper binding site 4 out
of 6 in 7rh7
Go back to
Copper Binding Sites List in 7rh7
Copper binding site 4 out
of 6 in the Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound
 Mono view
 Stereo pair view
|
|
A full contact list of Copper with other atoms in the Cu binding
site number 4 of Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
K:Cu401
b:51.7
occ:1.00
|
HG
|
K:CYS273
|
1.2
|
42.5
|
1.0
|
|
SG
|
K:CYS273
|
1.9
|
42.5
|
1.0
|
|
SG
|
K:CYS277
|
1.9
|
42.1
|
1.0
|
|
HE1
|
K:HIS281
|
2.0
|
42.3
|
1.0
|
|
ND1
|
K:HIS281
|
2.0
|
42.3
|
1.0
|
|
CE1
|
K:HIS281
|
2.2
|
42.3
|
1.0
|
|
HB3
|
K:CYS273
|
2.6
|
42.5
|
1.0
|
|
CB
|
K:CYS273
|
2.8
|
42.5
|
1.0
|
|
HB2
|
K:HIS232
|
3.0
|
43.4
|
1.0
|
|
HB2
|
K:CYS277
|
3.2
|
42.1
|
1.0
|
|
CB
|
K:CYS277
|
3.3
|
42.1
|
1.0
|
|
SD
|
K:MET284
|
3.3
|
43.9
|
1.0
|
|
CG
|
K:HIS281
|
3.3
|
42.3
|
1.0
|
|
HB2
|
K:CYS273
|
3.4
|
42.5
|
1.0
|
|
HE1
|
K:MET284
|
3.5
|
43.9
|
1.0
|
|
NE2
|
K:HIS281
|
3.5
|
42.3
|
1.0
|
|
HE2
|
K:MET284
|
3.6
|
43.9
|
1.0
|
|
HA
|
K:HIS281
|
3.7
|
42.3
|
1.0
|
|
CE
|
K:MET284
|
3.7
|
43.9
|
1.0
|
|
H
|
K:CYS277
|
3.7
|
42.1
|
1.0
|
|
CB
|
K:HIS232
|
3.8
|
43.4
|
1.0
|
|
H
|
K:GLU275
|
3.8
|
41.9
|
1.0
|
|
HB3
|
K:HIS232
|
3.8
|
43.4
|
1.0
|
|
N
|
K:CYS277
|
3.9
|
42.1
|
1.0
|
|
HB3
|
K:CYS277
|
3.9
|
42.1
|
1.0
|
|
O
|
K:HIS281
|
4.0
|
42.3
|
1.0
|
|
CD2
|
K:HIS281
|
4.0
|
42.3
|
1.0
|
|
HB2
|
K:MET284
|
4.1
|
43.9
|
1.0
|
|
CA
|
K:CYS273
|
4.1
|
42.5
|
1.0
|
|
H
|
K:GLY233
|
4.1
|
42.6
|
1.0
|
|
HE2
|
K:HIS281
|
4.1
|
42.3
|
1.0
|
|
CA
|
K:CYS277
|
4.2
|
42.1
|
1.0
|
|
CG
|
K:HIS232
|
4.2
|
43.4
|
1.0
|
|
HB3
|
K:GLU275
|
4.2
|
41.9
|
1.0
|
|
C
|
K:CYS273
|
4.2
|
42.5
|
1.0
|
|
CB
|
K:HIS281
|
4.2
|
42.3
|
1.0
|
|
ND1
|
K:HIS232
|
4.3
|
43.4
|
1.0
|
|
HB2
|
K:HIS281
|
4.3
|
42.3
|
1.0
|
|
CA
|
K:HIS281
|
4.3
|
42.3
|
1.0
|
|
O
|
K:CYS273
|
4.4
|
42.5
|
1.0
|
|
HA
|
K:CYS273
|
4.4
|
42.5
|
1.0
|
|
O
|
K:GLU275
|
4.5
|
41.9
|
1.0
|
|
HA
|
K:CYS277
|
4.5
|
42.1
|
1.0
|
|
C
|
K:MET276
|
4.5
|
40.5
|
1.0
|
|
CU
|
K:CU402
|
4.6
|
45.9
|
1.0
|
|
C
|
K:GLU275
|
4.6
|
41.9
|
1.0
|
|
N
|
K:GLU275
|
4.6
|
41.9
|
1.0
|
|
HB3
|
K:MET284
|
4.6
|
43.9
|
1.0
|
|
C
|
K:HIS281
|
4.6
|
42.3
|
1.0
|
|
CB
|
K:MET284
|
4.6
|
43.9
|
1.0
|
|
HE3
|
K:MET284
|
4.6
|
43.9
|
1.0
|
|
CG
|
K:MET284
|
4.6
|
43.9
|
1.0
|
|
HA
|
K:MET276
|
4.6
|
40.5
|
1.0
|
|
N
|
K:THR274
|
4.7
|
42.2
|
1.0
|
|
H
|
K:THR274
|
4.8
|
42.2
|
1.0
|
|
HE1
|
L:TYR461
|
4.8
|
41.1
|
1.0
|
|
HH
|
L:TYR461
|
4.9
|
41.1
|
1.0
|
|
N
|
K:GLY233
|
4.9
|
42.6
|
1.0
|
|
CA
|
K:MET276
|
5.0
|
40.5
|
1.0
|
|
CA
|
K:GLU275
|
5.0
|
41.9
|
1.0
|
|
N
|
K:MET276
|
5.0
|
40.5
|
1.0
|
|
HD2
|
K:HIS281
|
5.0
|
42.3
|
1.0
|
|
CB
|
K:GLU275
|
5.0
|
41.9
|
1.0
|
|
Copper binding site 5 out
of 6 in 7rh7
Go back to
Copper Binding Sites List in 7rh7
Copper binding site 5 out
of 6 in the Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound
 Mono view
 Stereo pair view
|
|
A full contact list of Copper with other atoms in the Cu binding
site number 5 of Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
K:Cu402
b:45.9
occ:1.00
|
CD2
|
K:HIS232
|
1.3
|
43.4
|
1.0
|
|
HD2
|
K:HIS232
|
1.4
|
43.4
|
1.0
|
|
NE2
|
K:HIS232
|
2.0
|
43.4
|
1.0
|
|
CG
|
K:HIS232
|
2.1
|
43.4
|
1.0
|
|
HE1
|
K:MET284
|
2.3
|
43.9
|
1.0
|
|
HE2
|
K:HIS232
|
2.4
|
43.4
|
1.0
|
|
CE1
|
K:HIS232
|
2.8
|
43.4
|
1.0
|
|
ND1
|
K:HIS232
|
2.8
|
43.4
|
1.0
|
|
HB3
|
K:HIS232
|
2.9
|
43.4
|
1.0
|
|
CB
|
K:HIS232
|
3.1
|
43.4
|
1.0
|
|
SG
|
K:CYS277
|
3.1
|
42.1
|
1.0
|
|
CE
|
K:MET284
|
3.2
|
43.9
|
1.0
|
|
HG11
|
K:VAL230
|
3.4
|
43.7
|
1.0
|
|
HE3
|
K:MET284
|
3.4
|
43.9
|
1.0
|
|
HB2
|
K:HIS232
|
3.5
|
43.4
|
1.0
|
|
HE1
|
K:HIS232
|
3.6
|
43.4
|
1.0
|
|
HB3
|
K:CYS277
|
3.6
|
42.1
|
1.0
|
|
HG13
|
K:VAL230
|
3.7
|
43.7
|
1.0
|
|
HE2
|
K:MET284
|
3.8
|
43.9
|
1.0
|
|
HG
|
K:CYS273
|
3.9
|
42.5
|
1.0
|
|
CG1
|
K:VAL230
|
3.9
|
43.7
|
1.0
|
|
O
|
K:PHE136
|
3.9
|
47.2
|
1.0
|
|
CB
|
K:CYS277
|
4.0
|
42.1
|
1.0
|
|
O
|
K:VAL230
|
4.0
|
43.7
|
1.0
|
|
H
|
K:TRP138
|
4.1
|
45.5
|
1.0
|
|
SD
|
K:MET284
|
4.1
|
43.9
|
1.0
|
|
O
|
K:ALA135
|
4.1
|
44.9
|
1.0
|
|
HG12
|
K:VAL230
|
4.2
|
43.7
|
1.0
|
|
HG
|
K:SER227
|
4.2
|
46.2
|
1.0
|
|
HA
|
K:GLN137
|
4.3
|
46.0
|
1.0
|
|
HA
|
K:CYS277
|
4.3
|
42.1
|
1.0
|
|
CA
|
K:HIS232
|
4.3
|
43.4
|
1.0
|
|
HG23
|
K:VAL245
|
4.3
|
44.1
|
1.0
|
|
O
|
K:ILE231
|
4.4
|
42.6
|
1.0
|
|
HB3
|
K:ALA135
|
4.4
|
44.9
|
1.0
|
|
N
|
K:HIS232
|
4.4
|
43.4
|
1.0
|
|
C
|
K:PHE136
|
4.5
|
47.2
|
1.0
|
|
HB2
|
K:ALA135
|
4.5
|
44.9
|
1.0
|
|
CU
|
K:CU401
|
4.6
|
51.7
|
1.0
|
|
SG
|
K:CYS273
|
4.6
|
42.5
|
1.0
|
|
HG21
|
K:VAL245
|
4.6
|
44.1
|
1.0
|
|
C
|
K:ILE231
|
4.6
|
42.6
|
1.0
|
|
C
|
K:ALA135
|
4.7
|
44.9
|
1.0
|
|
H
|
K:HIS232
|
4.7
|
43.4
|
1.0
|
|
HB2
|
K:CYS277
|
4.7
|
42.1
|
1.0
|
|
CA
|
K:CYS277
|
4.7
|
42.1
|
1.0
|
|
OG
|
K:SER227
|
4.7
|
46.2
|
1.0
|
|
H
|
K:VAL230
|
4.8
|
43.7
|
1.0
|
|
CG2
|
K:VAL245
|
4.8
|
44.1
|
1.0
|
|
CB
|
K:ALA135
|
4.9
|
44.9
|
1.0
|
|
N
|
K:TRP138
|
4.9
|
45.5
|
1.0
|
|
C
|
K:VAL230
|
4.9
|
43.7
|
1.0
|
|
OE1
|
K:GLN137
|
4.9
|
46.0
|
1.0
|
|
HB2
|
K:SER227
|
4.9
|
46.2
|
1.0
|
|
HA
|
K:HIS232
|
5.0
|
43.4
|
1.0
|
|
HG22
|
K:VAL245
|
5.0
|
44.1
|
1.0
|
|
HA
|
K:PHE136
|
5.0
|
47.2
|
1.0
|
|
Copper binding site 6 out
of 6 in 7rh7
Go back to
Copper Binding Sites List in 7rh7
Copper binding site 6 out
of 6 in the Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound
 Mono view
 Stereo pair view
|
|
A full contact list of Copper with other atoms in the Cu binding
site number 6 of Mycobacterial CIII2CIV2 Supercomplex, Telacebec (Q203) Bound within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
L:Cu602
b:67.3
occ:1.00
|
ND1
|
L:HIS264
|
2.0
|
39.6
|
1.0
|
|
NE2
|
L:HIS313
|
2.1
|
41.0
|
1.0
|
|
NE2
|
L:HIS314
|
2.1
|
40.2
|
1.0
|
|
CG
|
L:HIS264
|
2.2
|
39.6
|
1.0
|
|
HE1
|
L:HIS313
|
2.4
|
41.0
|
1.0
|
|
CE1
|
L:HIS313
|
2.4
|
41.0
|
1.0
|
|
CE1
|
L:HIS264
|
2.6
|
39.6
|
1.0
|
|
HB2
|
L:HIS264
|
2.6
|
39.6
|
1.0
|
|
CD2
|
L:HIS264
|
2.9
|
39.6
|
1.0
|
|
CB
|
L:HIS264
|
2.9
|
39.6
|
1.0
|
|
CE1
|
L:HIS314
|
3.0
|
40.2
|
1.0
|
|
NE2
|
L:HIS264
|
3.0
|
39.6
|
1.0
|
|
CD2
|
L:HIS314
|
3.1
|
40.2
|
1.0
|
|
HE1
|
L:HIS264
|
3.1
|
39.6
|
1.0
|
|
HE1
|
L:HIS314
|
3.2
|
40.2
|
1.0
|
|
CD2
|
L:HIS313
|
3.2
|
41.0
|
1.0
|
|
HD2
|
L:HIS314
|
3.3
|
40.2
|
1.0
|
|
HA
|
L:HIS264
|
3.4
|
39.6
|
1.0
|
|
ND1
|
L:HIS313
|
3.5
|
41.0
|
1.0
|
|
HD2
|
L:HIS264
|
3.5
|
39.6
|
1.0
|
|
HB3
|
L:HIS264
|
3.7
|
39.6
|
1.0
|
|
HD2
|
L:HIS313
|
3.7
|
41.0
|
1.0
|
|
HE2
|
L:HIS264
|
3.7
|
39.6
|
1.0
|
|
CA
|
L:HIS264
|
3.7
|
39.6
|
1.0
|
|
CG
|
L:HIS313
|
3.9
|
41.0
|
1.0
|
|
ND1
|
L:HIS314
|
4.1
|
40.2
|
1.0
|
|
HD1
|
L:HIS313
|
4.1
|
41.0
|
1.0
|
|
CG
|
L:HIS314
|
4.1
|
40.2
|
1.0
|
|
HG21
|
L:VAL267
|
4.2
|
38.1
|
1.0
|
|
HG22
|
L:VAL267
|
4.2
|
38.1
|
1.0
|
|
HA
|
L:TRP311
|
4.2
|
40.2
|
1.0
|
|
O
|
L:VAL310
|
4.4
|
40.8
|
1.0
|
|
O
|
L:TRP311
|
4.4
|
40.2
|
1.0
|
|
CG2
|
L:VAL267
|
4.6
|
38.1
|
1.0
|
|
HG13
|
L:VAL310
|
4.7
|
40.8
|
1.0
|
|
C
|
L:HIS264
|
4.7
|
39.6
|
1.0
|
|
N
|
L:HIS264
|
4.8
|
39.6
|
1.0
|
|
NA
|
L:HEA601
|
4.8
|
43.2
|
1.0
|
|
HD1
|
L:HIS314
|
4.8
|
40.2
|
1.0
|
|
H
|
L:HIS264
|
4.9
|
39.6
|
1.0
|
|
O
|
L:HIS264
|
4.9
|
39.6
|
1.0
|
|
HG23
|
L:VAL267
|
4.9
|
38.1
|
1.0
|
|
H
|
L:HIS313
|
4.9
|
41.0
|
1.0
|
|
HE3
|
L:TRP260
|
4.9
|
38.6
|
1.0
|
|
FE
|
L:HEA601
|
5.0
|
43.2
|
1.0
|
|
Reference:
D.J.Yanofsky,
J.M.Di Trani,
S.Krol,
R.Abdelaziz,
S.A.Bueler,
P.Imming,
P.Brzezinski,
J.L.Rubinstein.
Structure of Mycobacterial CIII2CIV2 Respiratory Supercomplex Bound to the Tuberculosis Drug Candidate Telacebec (Q203) To Be Published.
Page generated: Sat Aug 21 13:33:55 2021
|
