Copper in PDB 7prl: MUC2 D1 with Cu(II)

The structure of MUC2 D1 with Cu(II), PDB code: 7prl was solved by N.Reznik, D.Fass, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.17 / 2.48
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	95.9, 141.21, 68.52, 90, 90, 90
R / Rfree (%)	18.6 / 26

The binding sites of Copper atom in the MUC2 D1 with Cu(II) (pdb code 7prl). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total only one binding site of Copper was determined in the MUC2 D1 with Cu(II), PDB code: 7prl:

Copper binding site 1 out of 1 in the MUC2 D1 with Cu(II)


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of MUC2 D1 with Cu(II) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu406 b:53.0 occ:1.00 ND1 A:HIS277 2.0 52.2 1.0 NE2 A:HIS324 2.1 59.4 1.0 OE2 A:GLU156 2.3 60.5 1.0 ND1 A:HIS34 2.3 48.0 1.0 CE1 A:HIS277 2.8 60.3 1.0 CE1 A:HIS324 3.0 52.4 1.0 CG A:HIS34 3.0 55.1 1.0 CB A:HIS34 3.1 48.0 1.0 CD2 A:HIS324 3.2 45.1 1.0 CG A:HIS277 3.2 51.6 1.0 CD A:GLU156 3.2 65.0 1.0 CE1 A:HIS34 3.4 51.1 1.0 CB A:HIS277 3.7 51.5 1.0 CG A:GLU156 3.9 45.5 1.0 CA A:HIS277 3.9 53.6 1.0 NE2 A:HIS277 4.0 53.3 1.0 ND1 A:HIS324 4.1 56.7 1.0 OE1 A:GLU156 4.2 64.0 1.0 CD2 A:HIS277 4.2 53.9 1.0 O A:HIS277 4.2 49.8 1.0 CG A:HIS324 4.3 50.9 1.0 CD2 A:HIS34 4.3 52.5 1.0 NE2 A:HIS34 4.4 51.6 1.0 CG1 A:VAL36 4.4 46.1 1.0 CA A:HIS34 4.5 48.9 1.0 C A:HIS277 4.6 47.5 1.0 N A:HIS34 4.7 53.5 1.0 CB A:GLU156 5.0 33.9 1.0

N.Reznik, A.D.Gallo, K.W.Rush, G.Javitt, Y.Fridmann-Sirkis, T.Ilani, N.A.Nairner, S.Fishilevich, D.Gokhman, K.N.Chacon, K.J.Franz, D.Fass. Intestinal Mucin Is A Chaperone of Multivalent Copper. Cell V. 185 4206 2022.
ISSN: ISSN 1097-4172
PubMed: 36206754
DOI: 10.1016/J.CELL.2022.09.021