Copper in PDB 7m5b: Crystal Structure of Human Bak in Complex with M3W5_BID

The structure of Crystal Structure of Human Bak in Complex with M3W5_BID, PDB code: 7m5b was solved by G.Singh, A.Aggarwal, T.Moldoveanu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.08 / 1.85
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	50.19, 83.176, 110.03, 90, 90, 90
R / Rfree (%)	17 / 20.5

The binding sites of Copper atom in the Crystal Structure of Human Bak in Complex with M3W5_BID (pdb code 7m5b). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total only one binding site of Copper was determined in the Crystal Structure of Human Bak in Complex with M3W5_BID, PDB code: 7m5b:

Copper binding site 1 out of 1 in the Crystal Structure of Human Bak in Complex with M3W5_BID


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Crystal Structure of Human Bak in Complex with M3W5_BID within 5.0Å range: probe atom residue distance (Å) B Occ B:Cu201 b:17.4 occ:1.00 NE2 B:HIS89 2.0 14.7 1.0 NE2 D:HIS89 2.0 15.4 1.0 OE2 A:GLU92 2.2 32.6 1.0 OE1 C:GLU92 2.3 40.7 1.0 O D:HOH203 2.8 30.6 1.0 CD2 B:HIS89 2.8 12.6 1.0 CD2 D:HIS89 2.9 14.1 1.0 CE1 B:HIS89 3.1 14.8 1.0 CE1 D:HIS89 3.1 16.4 1.0 CD A:GLU92 3.2 35.5 1.0 CD C:GLU92 3.3 40.9 1.0 CG A:GLU92 3.7 28.9 1.0 CG C:GLU92 3.7 35.6 1.0 O B:HOH322 3.9 34.2 1.0 CG B:HIS89 4.1 11.2 1.0 CG D:HIS89 4.1 13.9 1.0 O C:HOH313 4.1 39.8 1.0 NH1 D:ARG88 4.1 21.2 1.0 ND1 B:HIS89 4.1 11.8 1.0 ND1 D:HIS89 4.2 13.6 1.0 NH1 B:ARG88 4.3 22.3 1.0 OE1 A:GLU92 4.3 42.6 1.0 OE2 C:GLU92 4.4 42.4 1.0 CB A:GLU92 4.5 22.1 1.0 CB C:GLU92 4.7 30.5 1.0 O D:HOH202 4.9 39.0 1.0 OE1 D:GLN92 4.9 16.7 1.0

G.Singh, C.D.Guibao, J.Seetharaman, A.Aggarwal, C.R.Grace, D.E.Mcnamara, S.Vaithiyalingam, M.B.Waddell, T.Moldoveanu. Structural Basis of Bak Activation in Mitochondrial Apoptosis Initiation. Nat Commun V. 13 250 2022.
ISSN: ESSN 2041-1723
PubMed: 35017502
DOI: 10.1038/S41467-021-27851-Y