Copper in PDB 7kf8: Cryo-Electron Microscopy Structure of the Heavy Metal Efflux Pump Cusa in A Heterogeneous 2 Open and 1 Closed Protomer Conformation

The binding sites of Copper atom in the Cryo-Electron Microscopy Structure of the Heavy Metal Efflux Pump Cusa in A Heterogeneous 2 Open and 1 Closed Protomer Conformation (pdb code 7kf8). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 2 binding sites of Copper where determined in the Cryo-Electron Microscopy Structure of the Heavy Metal Efflux Pump Cusa in A Heterogeneous 2 Open and 1 Closed Protomer Conformation, PDB code: 7kf8:
Jump to Copper binding site number: 1; 2;

Copper binding site 1 out of 2 in the Cryo-Electron Microscopy Structure of the Heavy Metal Efflux Pump Cusa in A Heterogeneous 2 Open and 1 Closed Protomer Conformation


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Cryo-Electron Microscopy Structure of the Heavy Metal Efflux Pump Cusa in A Heterogeneous 2 Open and 1 Closed Protomer Conformation within 5.0Å range: probe atom residue distance (Å) B Occ B:Cu1101 b:93.7 occ:1.00 SD B:MET623 2.1 56.9 1.0 HE1 B:MET672 2.4 60.0 1.0 OE2 B:GLU625 2.5 55.1 1.0 SD B:MET672 2.5 60.0 1.0 CE B:MET672 2.7 60.0 1.0 HE2 B:MET672 2.8 60.0 1.0 SD B:MET573 2.8 56.9 1.0 CE B:MET623 3.2 56.9 1.0 HE1 B:MET623 3.2 56.9 1.0 HE2 B:MET623 3.4 56.9 1.0 CG B:MET623 3.4 56.9 1.0 HE1 B:MET573 3.5 56.9 1.0 HG3 B:MET623 3.5 56.9 1.0 HG2 B:MET623 3.6 56.9 1.0 HE3 B:MET672 3.6 60.0 1.0 CE B:MET573 3.6 56.9 1.0 CD B:GLU625 3.6 55.1 1.0 HE3 B:MET573 3.7 56.9 1.0 HG3 B:GLU625 3.9 55.1 1.0 HD21 B:ASN668 4.0 59.1 1.0 HE3 B:MET623 4.0 56.9 1.0 CG B:MET672 4.1 60.0 1.0 HG3 B:MET672 4.1 60.0 1.0 CG B:MET573 4.2 56.9 1.0 CG B:GLU625 4.2 55.1 1.0 HG2 B:GLU625 4.2 55.1 1.0 HG3 B:MET573 4.3 56.9 1.0 HG2 B:MET573 4.3 56.9 1.0 HB2 B:ALA619 4.5 54.5 1.0 HE2 B:MET573 4.5 56.9 1.0 HG2 B:MET672 4.5 60.0 1.0 OE1 B:GLU625 4.7 55.1 1.0 CB B:MET623 4.7 56.9 1.0 ND2 B:ASN668 4.8 59.1 1.0 HB1 B:ALA619 4.9 54.5 1.0 HB3 B:MET623 4.9 56.9 1.0 HB2 B:MET623 5.0 56.9 1.0 HB3 B:MET672 5.0 60.0 1.0

Copper binding site 2 out of 2 in the Cryo-Electron Microscopy Structure of the Heavy Metal Efflux Pump Cusa in A Heterogeneous 2 Open and 1 Closed Protomer Conformation


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Cryo-Electron Microscopy Structure of the Heavy Metal Efflux Pump Cusa in A Heterogeneous 2 Open and 1 Closed Protomer Conformation within 5.0Å range: probe atom residue distance (Å) B Occ C:Cu1101 b:91.4 occ:1.00 HE2 C:MET672 2.0 60.8 1.0 HE1 C:MET672 2.2 60.8 1.0 CE C:MET672 2.2 60.8 1.0 SD C:MET623 2.4 58.0 1.0 SD C:MET672 2.4 60.8 1.0 SD C:MET573 2.4 58.9 1.0 OE2 C:GLU625 2.6 54.9 1.0 HE3 C:MET672 3.2 60.8 1.0 HE1 C:MET573 3.3 58.9 1.0 CE C:MET623 3.4 58.0 1.0 HE1 C:MET623 3.4 58.0 1.0 HE2 C:MET623 3.4 58.0 1.0 CE C:MET573 3.5 58.9 1.0 HG3 C:MET623 3.5 58.0 1.0 HG3 C:MET672 3.5 60.8 1.0 CG C:MET623 3.5 58.0 1.0 CG C:MET672 3.6 60.8 1.0 CD C:GLU625 3.7 54.9 1.0 HD21 C:ASN668 3.7 59.0 1.0 HG2 C:GLU625 3.7 54.9 1.0 HG2 C:MET623 3.8 58.0 1.0 HG3 C:GLU625 3.8 54.9 1.0 HG2 C:MET672 3.9 60.8 1.0 HE3 C:MET573 3.9 58.9 1.0 CG C:GLU625 4.0 54.9 1.0 CG C:MET573 4.0 58.9 1.0 HG3 C:MET573 4.1 58.9 1.0 HE3 C:MET623 4.2 58.0 1.0 HE2 C:MET573 4.3 58.9 1.0 HG2 C:MET573 4.3 58.9 1.0 ND2 C:ASN668 4.5 59.0 1.0 HB2 C:ALA619 4.6 56.6 1.0 OE1 C:GLU625 4.8 54.9 1.0 CB C:MET623 4.9 58.0 1.0 CB C:MET672 4.9 60.8 1.0 OD1 C:ASN668 4.9 59.0 1.0 HB3 C:MET672 5.0 60.8 1.0 HD22 C:ASN668 5.0 59.0 1.0

M.A.Moseng, M.Lyu, T.Pipatpolkai, P.Glaza, C.C.Emerson, P.L.Stewart, P.J.Stansfeld, E.W.Yu. Cryo-Em Structures of Cusa Reveal A Mechanism of Metal-Ion Export. Mbio V. 12 2021.
ISSN: ESSN 2150-7511
PubMed: 33820823
DOI: 10.1128/MBIO.00452-21