Copper in PDB 7kf6: Cryo-Electron Microscopy Structure of the Heavy Metal Efflux Pump Cusa in A Homogeneous Binding Copper(1) State

The binding sites of Copper atom in the Cryo-Electron Microscopy Structure of the Heavy Metal Efflux Pump Cusa in A Homogeneous Binding Copper(1) State (pdb code 7kf6). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 3 binding sites of Copper where determined in the Cryo-Electron Microscopy Structure of the Heavy Metal Efflux Pump Cusa in A Homogeneous Binding Copper(1) State, PDB code: 7kf6:
Jump to Copper binding site number: 1; 2; 3;

Copper binding site 1 out of 3 in the Cryo-Electron Microscopy Structure of the Heavy Metal Efflux Pump Cusa in A Homogeneous Binding Copper(1) State


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Cryo-Electron Microscopy Structure of the Heavy Metal Efflux Pump Cusa in A Homogeneous Binding Copper(1) State within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu1101 b:7.0 occ:1.00 OE2 A:GLU625 2.0 5.0 1.0 SD A:MET623 2.2 5.0 1.0 SD A:MET672 2.3 5.0 1.0 SD A:MET573 2.5 5.0 1.0 CD A:GLU625 3.2 5.0 1.0 HE3 A:MET573 3.3 161.3 1.0 CG A:MET672 3.3 5.0 1.0 CE A:MET672 3.4 5.0 1.0 HG3 A:MET672 3.4 166.1 1.0 HE1 A:MET672 3.4 166.1 1.0 HE3 A:MET623 3.4 160.5 1.0 HE2 A:MET672 3.5 166.1 1.0 HG2 A:MET672 3.5 166.1 1.0 CE A:MET623 3.5 5.0 1.0 CE A:MET573 3.5 5.0 1.0 CG A:MET623 3.7 5.0 1.0 HG2 A:MET623 3.8 160.5 1.0 HG2 A:GLU625 3.9 158.6 1.0 HG3 A:GLU625 3.9 158.6 1.0 CG A:GLU625 4.0 5.0 1.0 HE2 A:MET573 4.0 161.3 1.0 HE1 A:MET623 4.0 160.5 1.0 CG A:MET573 4.1 5.0 1.0 HD22 A:ASN668 4.1 169.5 1.0 HG3 A:MET623 4.1 160.5 1.0 HE2 A:MET623 4.2 160.5 1.0 OE1 A:GLU625 4.2 5.0 1.0 HG3 A:MET573 4.2 161.3 1.0 HE3 A:MET672 4.2 166.1 1.0 HE1 A:MET573 4.2 161.3 1.0 OD1 A:ASN668 4.2 5.0 1.0 HG2 A:MET573 4.5 161.3 1.0 ND2 A:ASN668 4.7 5.0 1.0 CB A:MET672 4.7 5.0 1.0 HB2 A:ALA619 4.7 157.5 1.0 HB3 A:MET672 4.8 166.1 1.0 HB3 A:MET623 4.8 160.5 1.0 CG A:ASN668 4.8 5.0 1.0 CB A:MET623 4.9 5.0 1.0

Copper binding site 2 out of 3 in the Cryo-Electron Microscopy Structure of the Heavy Metal Efflux Pump Cusa in A Homogeneous Binding Copper(1) State


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Cryo-Electron Microscopy Structure of the Heavy Metal Efflux Pump Cusa in A Homogeneous Binding Copper(1) State within 5.0Å range: probe atom residue distance (Å) B Occ B:Cu1101 b:6.9 occ:1.00 OE2 B:GLU625 1.8 5.0 1.0 SD B:MET623 2.2 5.0 1.0 SD B:MET672 2.4 5.0 1.0 SD B:MET573 2.5 5.0 1.0 CD B:GLU625 3.1 5.0 1.0 HE3 B:MET573 3.3 149.9 1.0 CE B:MET672 3.4 5.0 1.0 HE1 B:MET672 3.4 160.1 1.0 CG B:MET672 3.5 5.0 1.0 HE2 B:MET672 3.5 160.1 1.0 CE B:MET573 3.5 5.0 1.0 HG3 B:MET672 3.5 160.1 1.0 CG B:MET623 3.6 5.0 1.0 HG2 B:MET623 3.6 151.0 1.0 CE B:MET623 3.6 5.0 1.0 HE1 B:MET623 3.6 151.0 1.0 HG2 B:MET672 3.6 160.1 1.0 HG2 B:GLU625 3.8 149.7 1.0 CG B:GLU625 3.9 5.0 1.0 HE2 B:MET573 3.9 149.9 1.0 HG3 B:GLU625 3.9 149.7 1.0 OE1 B:GLU625 4.0 5.0 1.0 HG3 B:MET623 4.0 151.0 1.0 CG B:MET573 4.1 5.0 1.0 HE2 B:MET623 4.2 151.0 1.0 HE3 B:MET623 4.2 151.0 1.0 HG3 B:MET573 4.2 149.9 1.0 HE3 B:MET672 4.2 160.1 1.0 HD22 B:ASN668 4.3 163.4 1.0 HE1 B:MET573 4.3 149.9 1.0 OD1 B:ASN668 4.4 5.0 1.0 HG2 B:MET573 4.5 149.9 1.0 HB2 B:ALA619 4.6 150.8 1.0 HB3 B:MET623 4.6 151.0 1.0 CB B:MET623 4.7 5.0 1.0 CB B:MET672 4.8 5.0 1.0 ND2 B:ASN668 4.9 5.0 1.0 HB3 B:MET672 4.9 160.1 1.0

Copper binding site 3 out of 3 in the Cryo-Electron Microscopy Structure of the Heavy Metal Efflux Pump Cusa in A Homogeneous Binding Copper(1) State


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 3 of Cryo-Electron Microscopy Structure of the Heavy Metal Efflux Pump Cusa in A Homogeneous Binding Copper(1) State within 5.0Å range: probe atom residue distance (Å) B Occ C:Cu1101 b:7.4 occ:1.00 OE1 C:GLU625 2.1 5.0 1.0 SD C:MET623 2.2 5.0 1.0 SD C:MET672 2.2 5.0 1.0 SD C:MET573 2.7 5.0 1.0 CG C:MET672 3.2 5.0 1.0 HG3 C:MET672 3.2 162.3 1.0 CE C:MET672 3.3 5.0 1.0 CD C:GLU625 3.4 5.0 1.0 HE3 C:MET573 3.4 158.5 1.0 HG2 C:MET672 3.4 162.3 1.0 HE2 C:MET672 3.4 162.3 1.0 HE1 C:MET672 3.4 162.3 1.0 HE1 C:MET623 3.6 159.3 1.0 CE C:MET623 3.6 5.0 1.0 CG C:MET623 3.6 5.0 1.0 CE C:MET573 3.6 5.0 1.0 HG2 C:MET623 3.7 159.3 1.0 HG2 C:GLU625 3.9 155.4 1.0 HG3 C:MET623 4.0 159.3 1.0 HE2 C:MET573 4.0 158.5 1.0 CG C:GLU625 4.1 5.0 1.0 HG3 C:GLU625 4.1 155.4 1.0 HE2 C:MET623 4.1 159.3 1.0 HE3 C:MET672 4.2 162.3 1.0 HE3 C:MET623 4.3 159.3 1.0 OE2 C:GLU625 4.3 5.0 1.0 CG C:MET573 4.3 5.0 1.0 HD22 C:ASN668 4.4 166.6 1.0 HE1 C:MET573 4.4 158.5 1.0 OD1 C:ASN668 4.4 5.0 1.0 HG3 C:MET573 4.4 158.5 1.0 HB2 C:ALA619 4.5 157.2 1.0 CB C:MET672 4.6 5.0 1.0 HG2 C:MET573 4.6 158.5 1.0 HB3 C:MET672 4.7 162.3 1.0 HB3 C:MET623 4.8 159.3 1.0 CB C:MET623 4.9 5.0 1.0 HA C:MET672 4.9 162.3 1.0 ND2 C:ASN668 4.9 5.0 1.0

M.A.Moseng, M.Lyu, T.Pipatpolkai, P.Glaza, C.C.Emerson, P.L.Stewart, P.J.Stansfeld, E.W.Yu. Cryo-Em Structures of Cusa Reveal A Mechanism of Metal-Ion Export. Mbio V. 12 2021.
ISSN: ESSN 2150-7511
PubMed: 33820823
DOI: 10.1128/MBIO.00452-21