Copper in PDB 7atn: Cytochrome C Oxidase Structure in R-State

All present enzymatic activity of Cytochrome C Oxidase Structure in R-State:
7.1.1.9;

The structure of Cytochrome C Oxidase Structure in R-State also contains other interesting chemical elements:

Iron	(Fe)	2 atoms
Manganese	(Mn)	1 atom
Calcium	(Ca)	1 atom

The binding sites of Copper atom in the Cytochrome C Oxidase Structure in R-State (pdb code 7atn). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 3 binding sites of Copper where determined in the Cytochrome C Oxidase Structure in R-State, PDB code: 7atn:
Jump to Copper binding site number: 1; 2; 3;

Copper binding site 1 out of 3 in the Cytochrome C Oxidase Structure in R-State


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Cytochrome C Oxidase Structure in R-State within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu603 b:36.0 occ:1.00 ND1 A:HIS276 1.9 9.2 1.0 CE1 A:HIS276 2.2 9.2 1.0 NE2 A:HIS326 2.2 6.2 1.0 NE2 A:HIS325 2.5 7.1 1.0 CE1 A:HIS326 3.0 6.2 1.0 CG A:HIS276 3.2 9.2 1.0 CD2 A:HIS326 3.3 6.2 1.0 CE1 A:HIS325 3.4 7.1 1.0 NE2 A:HIS276 3.5 9.2 1.0 CD2 A:HIS325 3.5 7.1 1.0 NA A:HEA605 3.6 12.2 1.0 C1A A:HEA605 3.8 12.2 1.0 FE A:HEA605 3.9 12.2 1.0 CD2 A:HIS276 3.9 9.2 1.0 CB A:HIS276 4.0 9.2 1.0 C4A A:HEA605 4.1 12.2 1.0 ND1 A:HIS326 4.1 6.2 1.0 CHA A:HEA605 4.2 12.2 1.0 ND A:HEA605 4.2 12.2 1.0 CG A:HIS326 4.3 6.2 1.0 C4D A:HEA605 4.3 12.2 1.0 C2A A:HEA605 4.4 12.2 1.0 CA A:HIS276 4.4 9.2 1.0 C3A A:HEA605 4.5 12.2 1.0 NB A:HEA605 4.5 12.2 1.0 ND1 A:HIS325 4.6 7.1 1.0 O A:HOH746 4.6 9.9 1.0 CHB A:HEA605 4.6 12.2 1.0 CG A:HIS325 4.7 7.1 1.0 CG2 A:VAL279 4.8 9.3 1.0 C1B A:HEA605 4.8 12.2 1.0 NC A:HEA605 5.0 12.2 1.0

Copper binding site 2 out of 3 in the Cytochrome C Oxidase Structure in R-State


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Cytochrome C Oxidase Structure in R-State within 5.0Å range: probe atom residue distance (Å) B Occ B:Cu301 b:41.6 occ:1.00 CU1 B:CUA301 0.0 41.6 1.0 ND1 B:HIS224 2.1 8.2 1.0 O B:GLU218 2.6 13.7 1.0 CU2 B:CUA301 2.7 41.6 1.0 SG B:CYS220 2.8 10.6 1.0 CE1 B:HIS224 3.0 8.2 1.0 SG B:CYS216 3.0 9.2 1.0 CG B:HIS224 3.2 8.2 1.0 O B:HIS224 3.4 8.2 1.0 CB B:CYS220 3.4 10.6 1.0 CB B:CYS216 3.5 9.2 1.0 CA B:HIS224 3.5 8.2 1.0 CB B:HIS224 3.6 8.2 1.0 N B:CYS220 3.7 10.6 1.0 C B:GLU218 3.7 13.7 1.0 C B:HIS224 3.9 8.2 1.0 SD B:MET227 4.1 6.8 1.0 NE2 B:HIS224 4.1 8.2 1.0 CA B:CYS220 4.2 10.6 1.0 CD2 B:HIS224 4.2 8.2 1.0 C B:LEU219 4.4 7.1 1.0 CA B:LEU219 4.4 7.1 1.0 N B:GLU218 4.5 13.7 1.0 N B:LEU219 4.5 7.1 1.0 C B:CYS216 4.5 9.2 1.0 CG B:MET227 4.5 6.8 1.0 O B:CYS216 4.6 9.2 1.0 CA B:CYS216 4.6 9.2 1.0 ND1 B:HIS181 4.7 7.7 1.0 CA B:GLU218 4.7 13.7 1.0 N B:HIS224 4.8 8.2 1.0 N B:SER217 4.9 10.3 1.0

Copper binding site 3 out of 3 in the Cytochrome C Oxidase Structure in R-State


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 3 of Cytochrome C Oxidase Structure in R-State within 5.0Å range: probe atom residue distance (Å) B Occ B:Cu301 b:41.6 occ:1.00 CU2 B:CUA301 0.0 41.6 1.0 ND1 B:HIS181 2.1 7.7 1.0 SD B:MET227 2.6 6.8 1.0 CU1 B:CUA301 2.7 41.6 1.0 SG B:CYS216 2.8 9.2 1.0 SG B:CYS220 3.0 10.6 1.0 CE B:MET227 3.0 6.8 1.0 CE1 B:HIS181 3.1 7.7 1.0 CG B:HIS181 3.1 7.7 1.0 CB B:CYS220 3.3 10.6 1.0 CB B:HIS181 3.4 7.7 1.0 CB B:CYS216 3.8 9.2 1.0 CG B:MET227 3.9 6.8 1.0 CA B:HIS181 4.0 7.7 1.0 O B:GLU218 4.1 13.7 1.0 NE2 B:HIS181 4.2 7.7 1.0 CD2 B:HIS181 4.3 7.7 1.0 O B:ILE180 4.6 6.9 1.0 CA B:CYS220 4.8 10.6 1.0 ND1 B:HIS224 4.8 8.2 1.0 O B:HIS119 4.9 9.1 1.0 N B:ALA182 4.9 9.2 1.0 N B:HIS181 5.0 7.7 1.0

F.Kolbe, S.Safarian, H.Michel. Cytochrome C Oxidase Structure in R-State To Be Published.