Atomistry » Copper » PDB 6vow-6xx3 » 6xtr
Atomistry »
  Copper »
    PDB 6vow-6xx3 »
      6xtr »

Copper in PDB 6xtr: Crystal Structure Reveals Non-Coordinative Binding of O2 to the Copper Center of the Formylglycine-Generating Enzyme - Fge:Cu:S:O2-1C Complex

Enzymatic activity of Crystal Structure Reveals Non-Coordinative Binding of O2 to the Copper Center of the Formylglycine-Generating Enzyme - Fge:Cu:S:O2-1C Complex

All present enzymatic activity of Crystal Structure Reveals Non-Coordinative Binding of O2 to the Copper Center of the Formylglycine-Generating Enzyme - Fge:Cu:S:O2-1C Complex:
1.8.3.7;

Protein crystallography data

The structure of Crystal Structure Reveals Non-Coordinative Binding of O2 to the Copper Center of the Formylglycine-Generating Enzyme - Fge:Cu:S:O2-1C Complex, PDB code: 6xtr was solved by F.Leisinger, F.P.Seebeck, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.19 / 1.20
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 57.97, 71.674, 76.435, 90, 90, 90
R / Rfree (%) 18.9 / 20.6

Other elements in 6xtr:

The structure of Crystal Structure Reveals Non-Coordinative Binding of O2 to the Copper Center of the Formylglycine-Generating Enzyme - Fge:Cu:S:O2-1C Complex also contains other interesting chemical elements:

Calcium (Ca) 2 atoms
Chlorine (Cl) 2 atoms

Copper Binding Sites:

The binding sites of Copper atom in the Crystal Structure Reveals Non-Coordinative Binding of O2 to the Copper Center of the Formylglycine-Generating Enzyme - Fge:Cu:S:O2-1C Complex (pdb code 6xtr). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 2 binding sites of Copper where determined in the Crystal Structure Reveals Non-Coordinative Binding of O2 to the Copper Center of the Formylglycine-Generating Enzyme - Fge:Cu:S:O2-1C Complex, PDB code: 6xtr:
Jump to Copper binding site number: 1; 2;

Copper binding site 1 out of 2 in 6xtr

Go back to Copper Binding Sites List in 6xtr
Copper binding site 1 out of 2 in the Crystal Structure Reveals Non-Coordinative Binding of O2 to the Copper Center of the Formylglycine-Generating Enzyme - Fge:Cu:S:O2-1C Complex


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Crystal Structure Reveals Non-Coordinative Binding of O2 to the Copper Center of the Formylglycine-Generating Enzyme - Fge:Cu:S:O2-1C Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cu401

b:11.2
occ:0.76
 CU A:CU1401 0.0 11.2 0.8
CU A:CU1401 1.1 15.3 0.2
SG A:CYS274 2.0 17.0 0.2
SG C:CYS7 2.2 11.9 0.8
SG A:CYS269 2.3 13.4 1.0
SG A:CYS274 2.3 12.1 0.8
O2 A:OXY406 3.1 14.0 0.7
CB A:CYS274 3.2 12.8 0.8
CB A:CYS274 3.2 12.7 0.2
O1 A:OXY406 3.2 21.3 0.7
CB A:CYS269 3.3 13.3 1.0
CB C:CYS7 3.4 12.4 1.0
O A:HOH505 3.5 16.4 1.0
CA A:CYS269 3.6 12.0 1.0
CZ2 A:TRP228 3.8 12.1 1.0
CB A:ARG276 3.9 13.8 1.0
O A:HOH572 4.0 19.5 1.0
N A:CYS269 4.4 11.8 1.0
NE1 A:TRP228 4.4 11.5 1.0
CE2 A:TRP228 4.5 11.0 1.0
N A:ARG276 4.5 13.7 1.0
CA C:CYS7 4.6 12.6 1.0
CA A:CYS274 4.6 13.4 0.2
CA A:CYS274 4.6 13.4 0.8
CA A:ARG276 4.7 13.3 1.0
CG A:ARG276 4.7 14.1 1.0
CD A:ARG276 4.8 13.1 1.0
CH2 A:TRP228 4.8 11.8 1.0
C A:CYS269 4.9 11.8 1.0
C A:CYS274 4.9 14.1 0.2
NH1 A:ARG276 5.0 13.7 1.0
N A:HIS270 5.0 13.8 1.0

Copper binding site 2 out of 2 in 6xtr

Go back to Copper Binding Sites List in 6xtr
Copper binding site 2 out of 2 in the Crystal Structure Reveals Non-Coordinative Binding of O2 to the Copper Center of the Formylglycine-Generating Enzyme - Fge:Cu:S:O2-1C Complex


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Crystal Structure Reveals Non-Coordinative Binding of O2 to the Copper Center of the Formylglycine-Generating Enzyme - Fge:Cu:S:O2-1C Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cu401

b:15.3
occ:0.24
 CU A:CU1401 0.0 15.3 0.2
CU A:CU1401 1.1 11.2 0.8
SG A:CYS274 1.9 17.0 0.2
SG A:CYS269 2.0 13.4 1.0
SG A:CYS274 2.1 12.1 0.8
CB A:CYS269 2.8 13.3 1.0
SG C:CYS7 3.1 11.9 0.8
CB A:ARG276 3.2 13.8 1.0
CB A:CYS274 3.3 12.8 0.8
CB A:CYS274 3.3 12.7 0.2
CA A:CYS269 3.5 12.0 1.0
N A:ARG276 3.5 13.7 1.0
CA A:ARG276 3.7 13.3 1.0
O2 A:OXY406 3.8 14.0 0.7
CZ2 A:TRP228 3.9 12.1 1.0
C A:ARG276 4.1 15.0 1.0
O1 A:OXY406 4.1 21.3 0.7
CG A:ARG276 4.2 14.1 1.0
CB C:CYS7 4.3 12.4 1.0
C A:CYS274 4.4 14.1 0.2
N A:CYS269 4.4 11.8 1.0
CA A:CYS274 4.4 13.4 0.2
O A:ARG276 4.5 16.4 1.0
CA A:CYS274 4.5 13.4 0.8
O A:HOH505 4.5 16.4 1.0
C A:CYS274 4.5 14.1 0.8
C A:CYS269 4.6 11.8 1.0
N A:TYR277 4.6 14.6 1.0
CD A:ARG276 4.6 13.1 1.0
O A:HOH572 4.6 19.5 1.0
N A:HIS270 4.6 13.8 1.0
CH2 A:TRP228 4.7 11.8 1.0
CE2 A:TRP228 4.7 11.0 1.0
C A:ASN275 4.8 14.0 1.0
N A:ASN275 4.8 14.9 1.0
CA A:GLY265 4.8 10.2 1.0
NE1 A:TRP228 4.9 11.5 1.0
O A:CYS274 5.0 14.4 0.2
O A:CYS274 5.0 14.4 0.8

Reference:

F.Leisinger, D.A.Miarzlou, F.P.Seebeck. Crystal Structure Reveals Non-Coordinative Binding of O2 to the Copper Center of the Formylglycine-Generating Enzyme To Be Published.
Page generated: Mon Jul 14 07:30:57 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy