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Atomistry » Copper » PDB 5zpo-6ff2 » 6ehh » |
Copper in PDB 6ehh: Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588Enzymatic activity of Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588
All present enzymatic activity of Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588:
3.6.1.55; 3.6.1.56; Protein crystallography data
The structure of Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588, PDB code: 6ehh
was solved by
R.Gustafsson,
M.Narwal,
A.-S.Jemth,
I.Almlof,
U.Warpman Berglund,
T.Helleday,
P.Stenmark,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6ehh:
The structure of Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588 also contains other interesting chemical elements:
Copper Binding Sites:
The binding sites of Copper atom in the Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588
(pdb code 6ehh). This binding sites where shown within
5.0 Angstroms radius around Copper atom.
In total 4 binding sites of Copper where determined in the Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588, PDB code: 6ehh: Jump to Copper binding site number: 1; 2; 3; 4; Copper binding site 1 out of 4 in 6ehhGo back to Copper Binding Sites List in 6ehh
Copper binding site 1 out
of 4 in the Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588
Mono view Stereo pair view
Copper binding site 2 out of 4 in 6ehhGo back to Copper Binding Sites List in 6ehh
Copper binding site 2 out
of 4 in the Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588
Mono view Stereo pair view
Copper binding site 3 out of 4 in 6ehhGo back to Copper Binding Sites List in 6ehh
Copper binding site 3 out
of 4 in the Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588
Mono view Stereo pair view
Copper binding site 4 out of 4 in 6ehhGo back to Copper Binding Sites List in 6ehh
Copper binding site 4 out
of 4 in the Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588
Mono view Stereo pair view
Reference:
M.Narwal,
A.S.Jemth,
R.Gustafsson,
I.Almlof,
U.Warpman Berglund,
T.Helleday,
P.Stenmark.
Crystal Structures and Inhibitor Interactions of Mouse and Dog MTH1 Reveal Species-Specific Differences in Affinity. Biochemistry V. 57 593 2018.
Page generated: Sun Dec 13 11:22:12 2020
ISSN: ISSN 1520-4995 PubMed: 29281266 DOI: 10.1021/ACS.BIOCHEM.7B01163 |
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