Copper in PDB 6amp: Crystal Structure of H172A Phm (Cuh Absent, Cum Present)

All present enzymatic activity of Crystal Structure of H172A Phm (Cuh Absent, Cum Present):
1.14.17.3; 4.3.2.5;

The structure of Crystal Structure of H172A Phm (Cuh Absent, Cum Present), PDB code: 6amp was solved by S.Maheshwari, K.Rudzka, S.B.Gabelli, L.M.Amzel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.09 / 2.48
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	59.422, 66.362, 69.790, 90.00, 90.00, 90.00
R / Rfree (%)	21.3 / 29

The binding sites of Copper atom in the Crystal Structure of H172A Phm (Cuh Absent, Cum Present) (pdb code 6amp). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total only one binding site of Copper was determined in the Crystal Structure of H172A Phm (Cuh Absent, Cum Present), PDB code: 6amp:

Copper binding site 1 out of 1 in the Crystal Structure of H172A Phm (Cuh Absent, Cum Present)


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Crystal Structure of H172A Phm (Cuh Absent, Cum Present) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu401 b:94.0 occ:1.00 CE1 A:HIS244 2.1 81.4 1.0 NE2 A:HIS244 2.1 88.6 1.0 NE2 A:HIS242 2.1 58.7 1.0 SD A:MET314 2.3 70.2 1.0 CD2 A:HIS242 2.8 52.8 1.0 ND1 A:HIS244 3.2 73.9 1.0 CE1 A:HIS242 3.3 48.3 1.0 CD2 A:HIS244 3.3 80.3 1.0 CG A:MET314 3.5 63.1 1.0 CG A:HIS244 3.8 71.8 1.0 CE A:MET314 3.9 72.2 1.0 CB A:MET314 4.1 56.5 1.0 CG A:HIS242 4.1 49.3 1.0 ND1 A:HIS242 4.3 46.6 1.0

S.Maheshwari, C.Shimokawa, K.Rudzka, C.D.Kline, B.A.Eipper, R.E.Mains, S.B.Gabelli, N.Blackburn, L.M.Amzel. Effects of Copper Occupancy on the Conformational Landscape of Peptidylglycine Alpha-Hydroxylating Monooxygenase. Commun Biol V. 1 74 2018.
ISSN: ESSN 2399-3642
PubMed: 30271955
DOI: 10.1038/S42003-018-0082-Y