Copper in PDB 5vde: Crystal Structure of Cu(I)-Loaded Yeast ATX1: Crystal Form I

The structure of Crystal Structure of Cu(I)-Loaded Yeast ATX1: Crystal Form I, PDB code: 5vde was solved by M.Lee, M.J.Maher, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.65
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	35.976, 80.054, 50.763, 90.00, 99.91, 90.00
R / Rfree (%)	16.4 / 20.6

The binding sites of Copper atom in the Crystal Structure of Cu(I)-Loaded Yeast ATX1: Crystal Form I (pdb code 5vde). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 2 binding sites of Copper where determined in the Crystal Structure of Cu(I)-Loaded Yeast ATX1: Crystal Form I, PDB code: 5vde:
Jump to Copper binding site number: 1; 2;

Copper binding site 1 out of 2 in the Crystal Structure of Cu(I)-Loaded Yeast ATX1: Crystal Form I


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Crystal Structure of Cu(I)-Loaded Yeast ATX1: Crystal Form I within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu101 b:12.0 occ:1.00 SG B:CYS15 2.3 12.4 1.0 SG A:CYS15 2.3 12.2 1.0 SG A:CYS18 2.4 11.3 1.0 SG B:CYS18 2.4 11.6 1.0 CB B:CYS15 3.4 11.8 1.0 CB A:CYS15 3.5 10.6 1.0 N B:CYS18 3.5 11.6 1.0 N A:CYS18 3.5 11.8 1.0 CB B:CYS18 3.5 11.7 1.0 CB A:CYS18 3.6 11.5 1.0 N A:CYS15 3.7 11.9 1.0 N B:CYS15 3.8 11.7 1.0 CA B:CYS18 3.9 11.3 1.0 CA A:CYS18 4.0 11.7 1.0 CA B:CYS15 4.0 11.3 1.0 CA A:CYS15 4.1 11.5 1.0 C A:GLY17 4.2 15.2 1.0 OG1 A:THR14 4.3 15.5 0.5 O A:CYS15 4.4 12.4 1.0 C B:GLY17 4.4 13.1 1.0 C B:THR14 4.4 12.5 1.0 OG1 B:THR14 4.5 12.2 1.0 C A:CYS15 4.5 12.6 1.0 CA A:GLY17 4.5 14.8 1.0 C B:CYS15 4.5 12.1 1.0 O B:CYS15 4.5 12.3 1.0 C A:THR14 4.6 15.2 1.0 CB A:THR14 4.6 14.3 0.5 N A:GLY17 4.7 13.2 1.0 NZ A:LYS65 4.7 13.1 1.0 CA B:GLY17 4.7 13.1 1.0 N B:THR14 4.8 10.2 1.0 N B:GLY17 4.9 12.3 1.0 N A:THR14 4.9 14.2 1.0 CA A:THR14 4.9 14.4 0.5 CA B:THR14 5.0 11.7 1.0 O B:THR14 5.0 13.0 1.0

Copper binding site 2 out of 2 in the Crystal Structure of Cu(I)-Loaded Yeast ATX1: Crystal Form I


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Crystal Structure of Cu(I)-Loaded Yeast ATX1: Crystal Form I within 5.0Å range: probe atom residue distance (Å) B Occ C:Cu101 b:14.0 occ:1.00 SG C:CYS15 2.3 13.1 1.0 SG D:CYS15 2.3 13.1 1.0 SG D:CYS18 2.4 14.8 1.0 SG C:CYS18 2.4 14.0 1.0 CB D:CYS15 3.4 12.6 1.0 CB C:CYS15 3.5 13.2 1.0 N D:CYS18 3.5 14.3 1.0 N C:CYS18 3.5 14.6 1.0 CB D:CYS18 3.6 13.4 1.0 CB C:CYS18 3.6 12.7 1.0 N C:CYS15 3.8 14.2 1.0 N D:CYS15 3.8 13.5 1.0 CA D:CYS18 3.9 13.9 1.0 CA C:CYS18 4.0 12.7 1.0 CA D:CYS15 4.1 12.8 1.0 CA C:CYS15 4.1 13.3 1.0 OG1 C:THR14 4.2 19.7 0.5 C C:GLY17 4.3 16.5 1.0 OG1 D:THR14 4.4 18.1 1.0 C D:GLY17 4.4 14.3 1.0 C D:THR14 4.4 14.5 1.0 O C:CYS15 4.5 13.8 1.0 C C:CYS15 4.5 14.2 1.0 O D:CYS15 4.5 13.7 1.0 C D:CYS15 4.6 14.2 1.0 CA C:GLY17 4.6 16.7 1.0 CB C:THR14 4.6 14.9 0.5 NZ C:LYS65 4.7 24.1 1.0 N C:GLY17 4.8 16.2 1.0 C C:THR14 4.8 17.2 1.0 CA D:GLY17 4.8 13.9 1.0 N D:THR14 4.8 13.7 1.0 NZ D:LYS65 4.9 21.1 1.0 N D:GLY17 4.9 15.1 1.0

M.Lee, N.D.G.Cooray, M.J.Maher. The Crystal Structures of A Copper-Bound Metallochaperone From Saccharomyces Cerevisiae. J. Inorg. Biochem. V. 177 368 2017.
ISSN: ISSN 1873-3344
PubMed: 28865724
DOI: 10.1016/J.JINORGBIO.2017.08.009