Copper in PDB 4jhu: T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl

The structure of T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl, PDB code: 4jhu was solved by K.M.Polyakov, T.V.Fedorova, O.A.Glazunova, S.A.Kurzeev, L.G.Maloshenok, O.A.Koroleva, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.37 / 1.89
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	62.900, 84.420, 116.120, 90.00, 90.00, 90.00
R / Rfree (%)	16.6 / 21

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 14;

Binding sites:

The binding sites of Copper atom in the T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl (pdb code 4jhu). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 14 binding sites of Copper where determined in the T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl, PDB code: 4jhu:
Jump to Copper binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Copper binding site 1 out of 14 in the T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu501 b:19.1 occ:1.00 NE2 A:HIS449 2.0 17.6 1.0 NE2 A:HIS399 2.0 15.6 1.0 NE2 A:HIS111 2.0 15.6 1.0 O A:HOH934 2.4 17.6 0.5 CE1 A:HIS399 2.8 15.5 1.0 CD2 A:HIS449 2.9 17.4 1.0 CE1 A:HIS449 3.0 18.8 1.0 CE1 A:HIS111 3.0 17.1 1.0 CD2 A:HIS111 3.1 14.2 1.0 CD2 A:HIS399 3.1 15.8 1.0 ND1 A:HIS399 4.0 15.4 1.0 CD2 A:PHE447 4.0 17.1 1.0 CG A:HIS449 4.1 18.0 1.0 CD2 A:HIS397 4.1 16.4 1.0 ND1 A:HIS449 4.1 16.2 1.0 ND1 A:HIS111 4.1 14.3 1.0 CG A:HIS399 4.2 15.0 1.0 CG A:HIS111 4.2 14.4 1.0 CB A:PHE447 4.3 16.0 1.0 CD2 A:HIS64 4.5 14.1 1.0 CG A:PHE447 4.5 16.1 1.0 CG A:PRO79 4.6 14.1 1.0 CU A:CU504 4.6 19.8 1.0 NE2 A:HIS397 4.8 16.1 1.0 NE2 A:HIS64 4.8 15.8 1.0 O A:HOH921 4.9 19.1 1.0 CE2 A:PHE447 4.9 16.2 1.0 NE2 A:HIS451 4.9 15.7 1.0 CD2 A:HIS451 5.0 14.2 1.0 CE1 A:HIS109 5.0 13.6 1.0

Copper binding site 2 out of 14 in the T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu502 b:17.5 occ:1.00 ND1 A:HIS66 2.0 15.9 1.0 NE2 A:HIS109 2.0 13.4 1.0 NE2 A:HIS451 2.1 15.7 1.0 O A:HOH934 2.7 17.6 0.5 CE1 A:HIS66 2.9 13.1 1.0 CE1 A:HIS109 2.9 13.6 1.0 CE1 A:HIS451 3.0 16.6 1.0 CD2 A:HIS109 3.0 14.3 1.0 CG A:HIS66 3.0 15.4 1.0 CD2 A:HIS451 3.1 14.2 1.0 CB A:HIS66 3.4 14.4 1.0 CZ2 A:TRP107 3.6 13.6 1.0 CD2 A:HIS64 3.7 14.1 1.0 CE2 A:TRP107 3.9 14.1 1.0 NE1 A:TRP107 4.0 13.6 1.0 NE2 A:HIS66 4.0 14.6 1.0 ND1 A:HIS109 4.1 14.4 1.0 CU A:CU504 4.1 19.8 1.0 CD2 A:HIS66 4.1 15.7 1.0 CG A:HIS109 4.1 13.2 1.0 ND1 A:HIS451 4.1 15.9 1.0 CG A:HIS451 4.2 18.0 1.0 NE2 A:HIS64 4.3 15.8 1.0 CH2 A:TRP107 4.3 15.6 1.0 CD2 A:HIS397 4.3 16.4 1.0 CB A:ALA240 4.3 17.6 1.0 NE2 A:HIS397 4.5 16.1 1.0 CA A:HIS66 4.5 15.0 1.0 CD2 A:TRP107 4.8 13.2 1.0 CG A:HIS64 4.9 16.1 1.0

Copper binding site 3 out of 14 in the T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 3 of T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu503 b:20.5 occ:1.00 ND1 A:HIS455 2.0 18.6 1.0 ND1 A:HIS394 2.0 17.9 1.0 SG A:CYS450 2.2 19.6 1.0 CE1 A:HIS394 2.9 21.8 1.0 CE1 A:HIS455 3.0 17.8 1.0 CG A:HIS455 3.0 19.1 1.0 CG A:HIS394 3.1 18.1 1.0 CB A:CYS450 3.3 15.1 1.0 CB A:HIS455 3.4 20.4 1.0 CB A:HIS394 3.5 19.1 1.0 CD1 A:ILE452 3.5 19.4 1.0 CB A:ILE452 3.8 17.0 1.0 CD2 A:PHE460 3.8 19.6 1.0 CA A:HIS394 3.9 18.6 1.0 CG1 A:ILE452 4.0 19.6 1.0 NE2 A:HIS394 4.0 20.4 1.0 CE2 A:PHE460 4.1 20.8 1.0 NE2 A:HIS455 4.1 19.2 1.0 CD2 A:HIS394 4.1 18.6 1.0 CD2 A:HIS455 4.2 20.4 1.0 CG2 A:ILE452 4.6 20.6 1.0 CD A:PRO395 4.6 19.6 1.0 O A:GLY391 4.6 21.8 1.0 CA A:CYS450 4.7 16.5 1.0 N A:ILE452 4.8 16.8 1.0 CA A:HIS455 4.8 19.4 1.0 CA A:ILE452 4.9 16.1 1.0 CZ A:PHE336 4.9 21.7 1.0 O A:ILE452 4.9 20.7 1.0 C A:HIS394 4.9 18.8 1.0 N A:HIS394 4.9 19.5 1.0

Copper binding site 4 out of 14 in the T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 4 of T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu504 b:19.8 occ:1.00 NE2 A:HIS397 1.9 16.1 1.0 NE2 A:HIS64 1.9 15.8 1.0 O A:HOH603 2.5 15.9 1.0 CD2 A:HIS397 2.9 16.4 1.0 CE1 A:HIS64 2.9 15.7 1.0 CD2 A:HIS64 2.9 14.1 1.0 CE1 A:HIS397 2.9 17.4 1.0 ND1 A:HIS66 3.3 15.9 1.0 NE2 A:HIS399 3.4 15.6 1.0 CE1 A:HIS399 3.4 15.5 1.0 O A:HOH934 3.6 17.6 0.5 CG A:HIS66 3.6 15.4 1.0 ND1 A:HIS399 3.6 15.4 1.0 CD2 A:HIS399 3.6 15.8 1.0 CE1 A:HIS66 3.7 13.1 1.0 CG A:HIS399 3.7 15.0 1.0 CA A:HIS66 3.8 15.0 1.0 ND1 A:HIS64 4.0 14.8 1.0 ND1 A:HIS397 4.0 17.2 1.0 CG A:HIS397 4.0 17.4 1.0 CD2 A:HIS66 4.0 15.7 1.0 CG A:HIS64 4.0 16.1 1.0 N A:GLY67 4.0 15.8 1.0 CU A:CU502 4.1 17.5 1.0 CB A:HIS66 4.1 14.4 1.0 NE2 A:HIS66 4.1 14.6 1.0 C A:HIS66 4.4 16.2 1.0 O A:HOH635 4.5 17.6 1.0 O A:HOH652 4.5 16.6 1.0 CA A:HIS399 4.5 16.9 1.0 CU A:CU501 4.6 19.1 1.0 CB A:HIS399 4.6 15.8 1.0 N A:HIS66 4.9 13.6 1.0 N A:HIS399 5.0 15.2 1.0

Copper binding site 5 out of 14 in the T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 5 of T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu509 b:45.9 occ:1.00 NE2 A:HIS55 2.0 37.0 1.0 O A:HOH888 2.2 21.8 0.5 O A:HOH926 2.5 23.5 0.5 O A:HOH925 2.6 21.4 0.5 CE1 A:HIS55 2.8 36.1 1.0 CD2 A:HIS55 3.2 35.3 1.0 O A:HOH927 3.3 30.8 0.5 NZ A:LYS59 3.9 35.4 1.0 ND1 A:HIS55 4.0 35.9 1.0 CG A:HIS55 4.2 34.5 1.0 O A:ASN53 4.4 31.5 1.0 CD A:LYS59 4.8 27.4 1.0 O A:HOH930 4.8 36.6 1.0 CU A:CU515 4.9 42.9 1.0 CE A:LYS59 5.0 28.3 1.0 OD1 A:ASP495 5.0 30.3 1.0

Copper binding site 6 out of 14 in the T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 6 of T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu510 b:36.0 occ:0.50 OD1 A:ASP441 2.1 29.8 1.0 ND1 A:HIS401 2.1 25.8 1.0 O A:HOH658 2.3 29.8 1.0 O A:HOH895 2.3 25.6 0.5 O A:HOH939 2.4 27.4 0.5 O A:HOH887 2.6 22.9 0.5 CU A:CU514 2.7 48.6 0.5 CE1 A:HIS401 2.8 21.1 1.0 CG A:ASP441 3.1 31.8 1.0 CG A:HIS401 3.2 22.4 1.0 OD2 A:ASP441 3.3 41.6 1.0 O A:ARG439 3.7 26.8 1.0 CB A:HIS401 3.8 22.2 1.0 O A:GLY400 3.8 17.9 1.0 CA A:HIS401 4.0 22.4 1.0 NE2 A:HIS401 4.0 21.0 1.0 O A:HOH911 4.1 35.3 0.5 CD2 A:HIS401 4.2 22.3 1.0 O A:HOH769 4.4 32.2 1.0 CB A:ASN442 4.5 18.4 1.0 CB A:ASP441 4.6 28.7 1.0 N A:ASP441 4.6 22.1 1.0 C A:GLY400 4.8 19.4 1.0 N A:THR402 4.8 20.0 1.0 C A:ARG439 4.9 25.7 1.0 N A:HIS401 4.9 17.8 1.0

Copper binding site 7 out of 14 in the T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 7 of T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu511 b:37.4 occ:0.50 O A:HOH935 1.8 31.1 0.5 OD2 A:ASP378 2.0 32.6 1.0 O A:HOH883 2.2 35.3 1.0 CG A:ASP378 2.8 34.8 1.0 NH1 A:ARG439 2.9 61.5 1.0 OD1 A:ASP378 3.0 33.1 1.0 O A:HOH931 3.8 25.4 0.5 N A:GLY314 4.0 28.0 1.0 CA A:GLY314 4.1 30.9 1.0 CZ A:ARG439 4.3 58.3 1.0 CB A:ASP378 4.3 29.0 1.0 CU A:CU516 4.8 43.1 0.2

Copper binding site 8 out of 14 in the T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 8 of T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu512 b:44.1 occ:0.25 NE2 A:HIS71 2.0 38.3 1.0 CE1 A:HIS71 3.0 30.8 1.0 O A:HOH884 3.0 39.3 1.0 CD2 A:HIS71 3.0 38.8 1.0 ND1 A:HIS71 4.0 37.6 1.0 CG A:HIS71 4.1 29.2 1.0

Copper binding site 9 out of 14 in the T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 9 of T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu513 b:52.8 occ:0.50 OD2 A:ASP183 2.0 46.9 1.0 OD1 A:ASP183 2.7 41.3 1.0 CG A:ASP183 2.7 40.8 1.0 CB A:ASP183 4.2 33.8 1.0 O A:HOH932 4.3 44.8 1.0

Copper binding site 10 out of 14 in the T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 10 of T2-Depleted Laccase From Coriolopsis Caperata Soaked with Cucl within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu514 b:48.6 occ:0.50 O A:HOH939 1.8 27.4 0.5 OD2 A:ASP441 1.9 41.6 1.0 O A:HOH911 2.0 35.3 0.5 O A:HOH887 2.7 22.9 0.5 CU A:CU510 2.7 36.0 0.5 CG A:ASP441 2.8 31.8 1.0 OD1 A:ASP441 2.9 29.8 1.0 O A:HOH895 3.2 25.6 0.5 O A:HOH658 3.7 29.8 1.0 CB A:ASP441 4.2 28.7 1.0 O A:HOH769 4.4 32.2 1.0 ND1 A:HIS401 4.7 25.8 1.0 O A:ARG439 4.9 26.8 1.0

K.M.Polyakov, T.V.Fedorova, O.A.Glazunova, S.A.Kurzeev, L.G.Maloshenok, O.A.Koroleva. X-Ray Study of Copper Ions Incorporation in T2D Laccase From Coriolopsis Caperata To Be Published.