Copper in PDB 3x42: Crystal Structure of Copper Amine Oxidase From Arthrobacter Globiformis in the Presence of Sodium Bromide

All present enzymatic activity of Crystal Structure of Copper Amine Oxidase From Arthrobacter Globiformis in the Presence of Sodium Bromide:
1.4.3.21;

The structure of Crystal Structure of Copper Amine Oxidase From Arthrobacter Globiformis in the Presence of Sodium Bromide, PDB code: 3x42 was solved by T.Okajima, S.Nakanishi, T.Murakawa, M.Kataoka, H.Hayashi, A.Hamaguchi, T.Nakai, Y.Kawano, H.Yamaguchi, K.Tanizawa, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.74 / 1.88
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	192.684, 63.508, 158.099, 90.00, 117.55, 90.00
R / Rfree (%)	15.8 / 19

The structure of Crystal Structure of Copper Amine Oxidase From Arthrobacter Globiformis in the Presence of Sodium Bromide also contains other interesting chemical elements:

Potassium	(K)	2 atoms
Bromine	(Br)	8 atoms
Sodium	(Na)	2 atoms

The binding sites of Copper atom in the Crystal Structure of Copper Amine Oxidase From Arthrobacter Globiformis in the Presence of Sodium Bromide (pdb code 3x42). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 2 binding sites of Copper where determined in the Crystal Structure of Copper Amine Oxidase From Arthrobacter Globiformis in the Presence of Sodium Bromide, PDB code: 3x42:
Jump to Copper binding site number: 1; 2;

Copper binding site 1 out of 2 in the Crystal Structure of Copper Amine Oxidase From Arthrobacter Globiformis in the Presence of Sodium Bromide


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Crystal Structure of Copper Amine Oxidase From Arthrobacter Globiformis in the Presence of Sodium Bromide within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu701 b:14.9 occ:1.00 O A:HOH1041 1.9 22.9 1.0 NE2 A:HIS431 2.0 11.7 1.0 NE2 A:HIS433 2.0 10.7 1.0 ND1 A:HIS592 2.0 13.1 1.0 O A:HOH932 2.4 24.0 1.0 CD2 A:HIS433 3.0 14.9 1.0 CE1 A:HIS592 3.0 16.3 1.0 CD2 A:HIS431 3.0 12.6 1.0 CE1 A:HIS431 3.0 10.8 1.0 CG A:HIS592 3.1 12.8 1.0 CE1 A:HIS433 3.1 12.3 1.0 CB A:HIS592 3.4 14.1 1.0 O A:HOH1458 4.0 43.0 1.0 ND1 A:HIS431 4.1 11.7 1.0 NE2 A:HIS592 4.1 16.2 1.0 CG A:HIS433 4.1 8.8 1.0 CG A:HIS431 4.2 9.8 1.0 ND1 A:HIS433 4.2 10.6 1.0 CD2 A:HIS592 4.2 13.2 1.0 O A:HOH871 4.3 18.9 1.0 O A:HOH815 4.4 14.0 1.0 O2 A:TPQ382 4.7 18.3 1.0 SD A:MET602 4.9 23.3 1.0 CE A:MET602 4.9 27.9 1.0 CA A:HIS592 4.9 14.1 1.0

Copper binding site 2 out of 2 in the Crystal Structure of Copper Amine Oxidase From Arthrobacter Globiformis in the Presence of Sodium Bromide


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Crystal Structure of Copper Amine Oxidase From Arthrobacter Globiformis in the Presence of Sodium Bromide within 5.0Å range: probe atom residue distance (Å) B Occ B:Cu701 b:17.7 occ:1.00 ND1 B:HIS592 2.0 18.3 1.0 NE2 B:HIS431 2.0 14.2 1.0 O B:HOH1042 2.0 28.1 1.0 NE2 B:HIS433 2.1 13.4 1.0 O B:HOH859 2.4 26.0 1.0 CD2 B:HIS433 3.0 16.0 1.0 CE1 B:HIS592 3.0 19.6 1.0 CE1 B:HIS431 3.0 17.1 1.0 CD2 B:HIS431 3.0 16.6 1.0 CG B:HIS592 3.0 17.7 1.0 CE1 B:HIS433 3.1 15.5 1.0 CB B:HIS592 3.4 14.4 1.0 O B:HOH1332 3.9 35.2 1.0 ND1 B:HIS431 4.1 14.5 1.0 NE2 B:HIS592 4.1 17.2 1.0 CG B:HIS431 4.1 14.7 1.0 CG B:HIS433 4.1 13.5 1.0 CD2 B:HIS592 4.2 15.4 1.0 ND1 B:HIS433 4.2 12.9 1.0 O B:HOH845 4.3 20.4 1.0 O B:HOH840 4.3 17.8 1.0 O2 B:TPQ382 4.6 24.3 1.0 CE B:MET602 4.9 33.7 1.0 CA B:HIS592 4.9 16.7 1.0 SD B:MET602 4.9 24.8 1.0

T.Murakawa, A.Hamaguchi, S.Nakanishi, M.Kataoka, T.Nakai, Y.Kawano, H.Yamaguchi, H.Hayashi, K.Tanizawa, T.Okajima. Probing the Catalytic Mechanism of Copper Amine Oxidase From Arthrobacter Globiformis with Halide Ions J.Biol.Chem. 2015.
ISSN: ESSN 1083-351X
DOI: 10.1074/JBC.M115.662726