Atomistry » Copper » PDB 2z7y-3aws » 3aas
Atomistry »
  Copper »
    PDB 2z7y-3aws »
      3aas »

Copper in PDB 3aas: Bovine Beta-Trypsin Bound to Meta-Guanidino Schiff Base Copper (II) Chelate

Enzymatic activity of Bovine Beta-Trypsin Bound to Meta-Guanidino Schiff Base Copper (II) Chelate

All present enzymatic activity of Bovine Beta-Trypsin Bound to Meta-Guanidino Schiff Base Copper (II) Chelate:
3.4.21.4;

Protein crystallography data

The structure of Bovine Beta-Trypsin Bound to Meta-Guanidino Schiff Base Copper (II) Chelate, PDB code: 3aas was solved by D.Iyaguchi, S.Kawano, E.Toyota, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 1.75
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 53.990, 56.295, 65.742, 90.00, 90.00, 90.00
R / Rfree (%) 17.3 / 20.9

Other elements in 3aas:

The structure of Bovine Beta-Trypsin Bound to Meta-Guanidino Schiff Base Copper (II) Chelate also contains other interesting chemical elements:

Calcium (Ca) 1 atom

Copper Binding Sites:

The binding sites of Copper atom in the Bovine Beta-Trypsin Bound to Meta-Guanidino Schiff Base Copper (II) Chelate (pdb code 3aas). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total only one binding site of Copper was determined in the Bovine Beta-Trypsin Bound to Meta-Guanidino Schiff Base Copper (II) Chelate, PDB code: 3aas:

Copper binding site 1 out of 1 in 3aas

Go back to Copper Binding Sites List in 3aas
Copper binding site 1 out of 1 in the Bovine Beta-Trypsin Bound to Meta-Guanidino Schiff Base Copper (II) Chelate


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Bovine Beta-Trypsin Bound to Meta-Guanidino Schiff Base Copper (II) Chelate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cu3001

b:33.1
occ:1.00
OAK A:GUS1001 1.7 41.1 1.0
N A:GUS1001 1.9 42.1 1.0
OXT A:GUS1001 2.1 43.1 1.0
NE2 A:HIS40 2.3 18.9 1.0
O A:HOH303 2.8 19.6 1.0
CAJ A:GUS1001 2.8 41.3 1.0
C A:GUS1001 2.8 43.0 1.0
CA A:GUS1001 2.9 42.7 1.0
CAL A:GUS1001 2.9 42.3 1.0
CD2 A:HIS40 3.0 18.1 1.0
CAI A:GUS1001 3.2 41.0 1.0
CE1 A:HIS40 3.3 20.0 1.0
OG A:SER177 3.4 22.5 1.0
O A:HOH257 3.8 41.5 1.0
CB A:GUS1001 3.9 43.8 1.0
CAF A:GUS1001 4.0 40.3 1.0
CB A:SER177 4.0 18.5 1.0
O A:GUS1001 4.1 41.4 1.0
O A:SER192 4.1 15.7 1.0
CG A:HIS40 4.1 16.0 1.0
ND1 A:HIS40 4.3 17.2 1.0
CAH A:GUS1001 4.6 41.0 1.0
O A:HOH480 4.9 44.2 1.0
O A:HOH431 5.0 18.8 1.0

Reference:

D.Iyaguchi, S.Kawano, K.Takada, E.Toyota. Structural Basis For the Design of Novel Schiff Base Metal Chelate Inhibitors of Trypsin Bioorg.Med.Chem. V. 18 2076 2010.
ISSN: ISSN 0968-0896
PubMed: 20202854
DOI: 10.1016/J.BMC.2010.02.016
Page generated: Wed Oct 28 14:23:04 2020
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy