Copper in the structure of Crystal Structure of Homocitrate Synthase From Thermus Thermophilus Complexed With Alpha-Ketoglutarate (pdb 2ztj)

The binding sites of Copper atom in the structure of Crystal Structure of Homocitrate Synthase From Thermus Thermophilus Complexed With Alpha-Ketoglutarate (pdb code 2ztj). This binding sites where shown with 5.0 Angstroms radius around Copper atom. The 2ztj structure was solved by T.OKADA, T.TOMITA, T.KUZUYAMA, M.NISHIYAMA, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 30.7-1.8 Space group P6322 a (A) 135.645 b (A) 135.645 c (A) 127.102 alpha (°) 90.00 beta (°) 90.00 gamma (°) 120.00 Rfactor (%) 19.9 Rfree (%) 22.4 Copper Binding Sites: Copper binding site 1 out of 1 in 2ztj Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Copper in the PDB 2ztj. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Arg12, A: Glu13, A: His195, A: His197, A: Ile231, A: Akg383, A: Hoh428, A: Hoh450, A: Hoh468, conact list: Atom Atom Distance (A) Cu CZ A:Arg12 4.75 Cu NH2 A:Arg12 4.22 Cu NH1 A:Arg12 4.30 Cu OE1 A:Glu13 2.18 Cu CB A:Glu13 4.98 Cu OE2 A:Glu13 3.44 Cu CD A:Glu13 3.11 Cu CG A:Glu13 4.40 Cu NE2 A:His195 2.19 Cu ND1 A:His195 4.20 Cu CD2 A:His195 3.23 Cu CE1 A:His195 3.07 Cu CG A:His195 4.31 Cu NE2 A:His197 2.13 Cu ND1 A:His197 4.23 Cu CD2 A:His197 3.08 Cu CE1 A:His197 3.13 Cu CG A:His197 4.23 Cu CG2 A:Ile231 4.21 Cu O5 A:Akg383 2.10 Cu O2 A:Akg383 4.17 Cu C4 A:Akg383 4.48 Cu C1 A:Akg383 2.94 Cu O1 A:Akg383 2.25 Cu C3 A:Akg383 4.23 Cu C2 A:Akg383 2.84 Cu O A:Hoh428 2.27 Cu O A:Hoh450 3.94 Cu O A:Hoh468 4.30 interactive model: