Atomistry » Copper » PDB 2z7y-3aws » 2z8y
Atomistry »
  Copper »
    PDB 2z7y-3aws »
      2z8y »

Copper in PDB 2z8y: Xenon-Bound Structure of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-Coa Synthase(Codh/Acs) From Moorella Thermoacetica

Enzymatic activity of Xenon-Bound Structure of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-Coa Synthase(Codh/Acs) From Moorella Thermoacetica

All present enzymatic activity of Xenon-Bound Structure of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-Coa Synthase(Codh/Acs) From Moorella Thermoacetica:
1.2.7.4; 1.2.99.2; 2.3.1.169;

Protein crystallography data

The structure of Xenon-Bound Structure of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-Coa Synthase(Codh/Acs) From Moorella Thermoacetica, PDB code: 2z8y was solved by T.I.Doukov, L.C.Blasiak, C.L.Drennan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 49.00 / 2.51
Space group P 1
Cell size a, b, c (Å), α, β, γ (°) 99.540, 136.600, 141.750, 101.29, 109.22, 103.91
R / Rfree (%) 17.8 / 25

Other elements in 2z8y:

The structure of Xenon-Bound Structure of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-Coa Synthase(Codh/Acs) From Moorella Thermoacetica also contains other interesting chemical elements:

Nickel (Ni) 8 atoms
Xenon (Xe) 42 atoms
Iron (Fe) 56 atoms

Copper Binding Sites:

The binding sites of Copper atom in the Xenon-Bound Structure of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-Coa Synthase(Codh/Acs) From Moorella Thermoacetica (pdb code 2z8y). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 4 binding sites of Copper where determined in the Xenon-Bound Structure of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-Coa Synthase(Codh/Acs) From Moorella Thermoacetica, PDB code: 2z8y:
Jump to Copper binding site number: 1; 2; 3; 4;

Copper binding site 1 out of 4 in 2z8y

Go back to Copper Binding Sites List in 2z8y
Copper binding site 1 out of 4 in the Xenon-Bound Structure of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-Coa Synthase(Codh/Acs) From Moorella Thermoacetica


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Xenon-Bound Structure of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-Coa Synthase(Codh/Acs) From Moorella Thermoacetica within 5.0Å range:
probe atom residue distance (Å) B Occ
M:Cu950

b:30.4
occ:1.00
SG M:CYS597 2.1 20.9 1.0
SG M:CYS509 2.2 21.9 1.0
SG M:CYS595 2.3 20.2 1.0
S3 M:SF4900 2.8 20.6 1.0
NI M:NI951 3.0 18.4 1.0
FE4 M:SF4900 3.0 14.9 1.0
CB M:CYS509 3.2 19.3 1.0
CB M:CYS595 3.5 17.6 1.0
CB M:CYS597 3.6 18.6 1.0
XE M:XE1008 3.6 31.0 0.8
N M:CYS597 4.3 16.9 1.0
CD1 M:ILE146 4.3 13.2 1.0
CD1 M:LEU527 4.4 14.4 1.0
FE1 M:SF4900 4.5 13.4 1.0
CA M:CYS597 4.5 19.0 1.0
N M:GLY596 4.5 16.5 1.0
CA M:CYS509 4.6 20.2 1.0
S2 M:SF4900 4.6 15.2 1.0
FE2 M:SF4900 4.6 15.4 1.0
S1 M:SF4900 4.8 14.6 1.0
CA M:CYS595 4.8 17.5 1.0
CB M:CYS528 5.0 19.5 1.0

Copper binding site 2 out of 4 in 2z8y

Go back to Copper Binding Sites List in 2z8y
Copper binding site 2 out of 4 in the Xenon-Bound Structure of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-Coa Synthase(Codh/Acs) From Moorella Thermoacetica


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Xenon-Bound Structure of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-Coa Synthase(Codh/Acs) From Moorella Thermoacetica within 5.0Å range:
probe atom residue distance (Å) B Occ
N:Cu950

b:28.3
occ:1.00
SG N:CYS509 2.2 17.6 1.0
SG N:CYS595 2.3 22.5 1.0
SG N:CYS597 2.4 18.9 1.0
NI N:NI951 2.9 18.0 1.0
S3 N:SF4900 3.0 17.4 1.0
FE4 N:SF4900 3.0 16.6 1.0
CB N:CYS509 3.2 16.8 1.0
CB N:CYS595 3.5 20.7 1.0
XE N:XE1009 3.7 34.8 0.7
CB N:CYS597 3.7 16.5 1.0
N N:CYS597 4.4 17.5 1.0
CD1 N:ILE146 4.6 25.8 1.0
FE1 N:SF4900 4.6 14.0 1.0
CA N:CYS509 4.6 18.0 1.0
N N:GLY596 4.6 17.8 1.0
FE2 N:SF4900 4.6 16.7 1.0
S2 N:SF4900 4.7 13.3 1.0
CD1 N:LEU527 4.7 14.6 1.0
CA N:CYS597 4.7 16.2 1.0
S1 N:SF4900 4.7 13.4 1.0
CA N:CYS595 4.8 20.6 1.0
CB N:CYS528 4.9 17.9 1.0
CD2 N:HIS516 5.0 9.4 1.0

Copper binding site 3 out of 4 in 2z8y

Go back to Copper Binding Sites List in 2z8y
Copper binding site 3 out of 4 in the Xenon-Bound Structure of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-Coa Synthase(Codh/Acs) From Moorella Thermoacetica


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 3 of Xenon-Bound Structure of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-Coa Synthase(Codh/Acs) From Moorella Thermoacetica within 5.0Å range:
probe atom residue distance (Å) B Occ
O:Cu950

b:88.5
occ:1.00
XE O:XE1009 2.0 42.3 0.4
SG O:CYS597 2.5 55.8 1.0
SG O:CYS509 2.6 46.3 1.0
NI O:NI951 2.7 76.0 1.0
SG O:CYS595 2.7 62.8 1.0
CB O:CYS597 2.8 57.0 1.0
N O:CYS597 2.9 59.0 1.0
CB O:CYS509 3.4 50.3 1.0
CA O:CYS597 3.4 57.2 1.0
CB O:CYS595 3.4 57.9 1.0
N O:GLY596 3.8 60.8 1.0
C O:GLY596 3.9 59.6 1.0
C O:CYS595 4.1 59.9 1.0
CA O:GLY596 4.2 59.9 1.0
CA O:CYS595 4.3 59.1 1.0
CA O:CYS509 4.5 50.7 1.0
CD1 O:PHE229 4.6 50.0 1.0
C O:CYS597 4.7 56.3 1.0
CE1 O:PHE229 4.8 53.5 1.0
S3 O:SF4900 4.8 60.0 1.0
CG1 O:VAL149 4.9 54.9 1.0
O O:GLY596 4.9 59.8 1.0
O O:CYS595 4.9 60.6 1.0
FE4 O:SF4900 4.9 61.1 1.0

Copper binding site 4 out of 4 in 2z8y

Go back to Copper Binding Sites List in 2z8y
Copper binding site 4 out of 4 in the Xenon-Bound Structure of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-Coa Synthase(Codh/Acs) From Moorella Thermoacetica


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 4 of Xenon-Bound Structure of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-Coa Synthase(Codh/Acs) From Moorella Thermoacetica within 5.0Å range:
probe atom residue distance (Å) B Occ
P:Cu950

b:52.6
occ:1.00
SG P:CYS509 2.1 30.9 1.0
SG P:CYS595 2.3 41.3 1.0
SG P:CYS597 2.5 37.6 1.0
NI P:NI951 2.9 44.5 1.0
FE4 P:SF4900 3.0 31.9 1.0
S3 P:SF4900 3.0 33.5 1.0
CB P:CYS509 3.3 34.4 1.0
XE P:XE1009 3.5 31.9 0.5
CB P:CYS595 3.5 39.9 1.0
CB P:CYS597 3.9 32.9 1.0
CD1 P:LEU527 4.6 36.9 1.0
FE1 P:SF4900 4.6 37.5 1.0
S2 P:SF4900 4.7 35.4 1.0
CA P:CYS509 4.7 35.6 1.0
N P:CYS597 4.7 34.6 1.0
N P:GLY596 4.7 37.4 1.0
FE2 P:SF4900 4.7 32.6 1.0
CA P:CYS595 4.8 39.8 1.0
S1 P:SF4900 4.9 36.8 1.0
CA P:CYS597 4.9 33.6 1.0

Reference:

T.I.Doukov, L.C.Blasiak, J.Seravalli, S.W.Ragsdale, C.L.Drennan. Xenon in and at the End of the Tunnel of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-Coa Synthase Biochemistry V. 47 3474 2008.
ISSN: ISSN 0006-2960
PubMed: 18293927
DOI: 10.1021/BI702386T
Page generated: Sun Dec 13 11:08:25 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy