Copper in the structure of Copper Chaperone ATX1 From Synechocystis PCC6803 (CU2 Form) (pdb 2xmu)

The binding sites of Copper atom in the structure of Copper Chaperone ATX1 From Synechocystis PCC6803 (CU2 Form) (pdb code 2xmu). This binding sites where shown with 5.0 Angstroms radius around Copper atom. The 2xmu structure was solved by A.BADARAU, S.J.FIRBANK, A.A.MCCARTHY, M.J.BANFIELD, C.DENNISON, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 37.6-1.8 Space group P1 a (A) 29.243 b (A) 29.388 c (A) 38.702 alpha (°) 91.69 beta (°) 101.26 gamma (°) 118.62 Rfactor (%) 26.707 Rfree (%) 31.157 Copper Binding Sites: Copper binding site 1 out of 4 in 2xmu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Copper in the PDB 2xmu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Ala11, A: Cys12, A: Glu13, A: Ala14, A: Cys15, B: Cys12, B: Cys15, B: His61, A: Cu1102, B: Cu1101, B: Cu1102, conact list: Atom Atom Distance (A) Cu O A:Ala11 4.86 Cu N A:Ala11 4.07 Cu C A:Ala11 4.00 Cu CB A:Ala11 4.43 Cu CA A:Ala11 4.35 Cu O A:Cys12 3.60 Cu N A:Cys12 3.21 Cu CB A:Cys12 3.22 Cu SG A:Cys12 2.13 Cu C A:Cys12 3.76 Cu CA A:Cys12 3.52 Cu N A:Glu13 4.72 Cu N A:Ala14 4.45 Cu C A:Ala14 4.13 Cu CB A:Ala14 4.18 Cu CA A:Ala14 4.48 Cu N A:Cys15 3.19 Cu CB A:Cys15 3.23 Cu SG A:Cys15 2.13 Cu CA A:Cys15 3.67 Cu SG B:Cys12 4.89 Cu N B:Cys15 4.79 Cu CB B:Cys15 4.41 Cu SG B:Cys15 2.98 Cu CA B:Cys15 4.69 Cu NE2 B:His61 4.25 Cu CE1 B:His61 4.69 Cu CU A:Cu1102 3.90 Cu CU B:Cu1101 3.12 Cu CU B:Cu1102 2.52 interactive model: Copper binding site 2 out of 4 in 2xmu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Copper in the PDB 2xmu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Ile10, A: Cys15, A: Ala59, A: His61, B: Ala11, B: Cys12, B: Cys15, A: Cu1101, B: Cu1101, conact list: Atom Atom Distance (A) Cu CD1 A:Ile10 4.78 Cu CA A:Ile10 4.97 Cu O A:Cys15 4.89 Cu N A:Cys15 4.41 Cu CB A:Cys15 2.94 Cu SG A:Cys15 2.14 Cu C A:Cys15 4.65 Cu CA A:Cys15 3.50 Cu O A:Ala59 4.64 Cu NE2 A:His61 1.92 Cu ND1 A:His61 3.84 Cu CD2 A:His61 3.14 Cu CE1 A:His61 2.61 Cu CG A:His61 4.10 Cu C B:Ala11 4.67 Cu CB B:Ala11 4.34 Cu N B:Cys12 4.29 Cu CB B:Cys12 3.33 Cu SG B:Cys12 2.39 Cu CA B:Cys12 4.40 Cu SG B:Cys15 4.37 Cu CU A:Cu1101 3.90 Cu CU B:Cu1101 2.46 interactive model: Copper binding site 3 out of 4 in 2xmu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 3 of Copper in the PDB 2xmu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Cys12, A: Cys15, A: His61, B: Ala11, B: Cys12, B: Glu13, B: Ala14, B: Cys15, A: Cu1101, A: Cu1102, B: Cu1102, conact list: Atom Atom Distance (A) Cu SG A:Cys12 4.83 Cu N A:Cys15 4.77 Cu CB A:Cys15 4.32 Cu SG A:Cys15 2.85 Cu CA A:Cys15 4.62 Cu NE2 A:His61 4.23 Cu CE1 A:His61 4.58 Cu O B:Ala11 4.93 Cu N B:Ala11 4.03 Cu C B:Ala11 3.99 Cu CB B:Ala11 4.14 Cu CA B:Ala11 4.25 Cu O B:Cys12 3.70 Cu N B:Cys12 3.15 Cu CB B:Cys12 3.31 Cu SG B:Cys12 2.24 Cu C B:Cys12 3.84 Cu CA B:Cys12 3.57 Cu N B:Glu13 4.83 Cu N B:Ala14 4.59 Cu C B:Ala14 4.17 Cu CB B:Ala14 4.32 Cu CA B:Ala14 4.56 Cu N B:Cys15 3.23 Cu CB B:Cys15 3.23 Cu SG B:Cys15 2.14 Cu CA B:Cys15 3.72 Cu CU A:Cu1101 3.12 Cu CU A:Cu1102 2.46 Cu CU B:Cu1102 3.84 interactive model: Copper binding site 4 out of 4 in 2xmu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 4 of Copper in the PDB 2xmu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Ala11, A: Cys12, A: Ala14, A: Cys15, B: Ile10, B: Cys15, B: Ala59, B: His61, A: Cu1101, B: Cu1101, conact list: Atom Atom Distance (A) Cu C A:Ala11 4.74 Cu CB A:Ala11 4.65 Cu N A:Cys12 4.45 Cu CB A:Cys12 3.40 Cu SG A:Cys12 2.44 Cu CA A:Cys12 4.51 Cu CB A:Ala14 4.93 Cu SG A:Cys15 4.36 Cu CA B:Ile10 4.83 Cu O B:Cys15 4.88 Cu N B:Cys15 4.35 Cu CB B:Cys15 2.94 Cu SG B:Cys15 2.14 Cu C B:Cys15 4.65 Cu CA B:Cys15 3.47 Cu O B:Ala59 4.48 Cu NE2 B:His61 1.94 Cu ND1 B:His61 3.92 Cu CD2 B:His61 3.12 Cu CE1 B:His61 2.73 Cu CG B:His61 4.13 Cu CU A:Cu1101 2.52 Cu CU B:Cu1101 3.84 interactive model: