Copper in PDB 2xl7: Structure and Metal-Loading of A Soluble Periplasm Cupro- Protein: Cu-Cuca-Closed (Semet)

The structure of Structure and Metal-Loading of A Soluble Periplasm Cupro- Protein: Cu-Cuca-Closed (Semet), PDB code: 2xl7 was solved by K.J.Waldron, S.J.Firbank, S.J.Dainty, M.Perez-Rama, S.Tottey, N.J.Robinson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.24 / 2.40
Space group	P 64 2 2
Cell size a, b, c (Å), α, β, γ (°)	88.483, 88.483, 192.419, 90.00, 90.00, 120.00
R / Rfree (%)	17.417 / 21.317

The structure of Structure and Metal-Loading of A Soluble Periplasm Cupro- Protein: Cu-Cuca-Closed (Semet) also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Copper atom in the Structure and Metal-Loading of A Soluble Periplasm Cupro- Protein: Cu-Cuca-Closed (Semet) (pdb code 2xl7). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 2 binding sites of Copper where determined in the Structure and Metal-Loading of A Soluble Periplasm Cupro- Protein: Cu-Cuca-Closed (Semet), PDB code: 2xl7:
Jump to Copper binding site number: 1; 2;

Copper binding site 1 out of 2 in the Structure and Metal-Loading of A Soluble Periplasm Cupro- Protein: Cu-Cuca-Closed (Semet)


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Structure and Metal-Loading of A Soluble Periplasm Cupro- Protein: Cu-Cuca-Closed (Semet) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu1269 b:21.8 occ:1.00 NE2 A:HIS88 2.0 27.0 1.0 OE1 A:GLU95 2.0 29.6 1.0 NE2 A:HIS90 2.1 25.7 1.0 NE2 A:HIS149 2.2 30.5 1.0 CD2 A:HIS88 3.0 26.4 1.0 CE1 A:HIS88 3.0 24.2 1.0 CD A:GLU95 3.0 28.5 1.0 CD2 A:HIS90 3.0 26.0 1.0 O A:HOH2047 3.1 55.9 1.0 CE1 A:HIS90 3.1 24.5 1.0 CD2 A:HIS149 3.2 29.6 1.0 OE2 A:GLU95 3.3 29.1 1.0 CE1 A:HIS149 3.3 31.4 1.0 ND1 A:HIS88 4.1 25.9 1.0 CG A:HIS88 4.1 26.2 1.0 CG A:HIS90 4.2 26.1 1.0 ND1 A:HIS90 4.2 26.1 1.0 CG A:HIS149 4.3 28.9 1.0 ND1 A:HIS149 4.4 31.3 1.0 CG A:GLU95 4.4 26.8 1.0 CZ A:PHE97 4.4 23.8 1.0 N1 A:URE1271 4.5 33.5 1.0 NE1 A:TRP165 4.6 23.7 1.0 CB A:GLU95 4.7 26.0 1.0 CE1 A:PHE97 4.9 24.4 1.0 CD1 A:TRP165 5.0 23.8 1.0

Copper binding site 2 out of 2 in the Structure and Metal-Loading of A Soluble Periplasm Cupro- Protein: Cu-Cuca-Closed (Semet)


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Structure and Metal-Loading of A Soluble Periplasm Cupro- Protein: Cu-Cuca-Closed (Semet) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu1270 b:35.5 occ:1.00 ND1 A:HIS36 1.9 38.3 1.0 O A:HOH2003 2.6 46.0 1.0 CE1 A:HIS36 2.8 38.6 1.0 CG A:HIS36 2.9 36.1 1.0 CB A:HIS36 3.4 33.5 1.0 CA A:HIS36 3.6 33.3 1.0 NE2 A:HIS36 3.9 38.0 1.0 CD2 A:HIS36 4.0 37.2 1.0 O A:ILE35 4.4 35.3 1.0 N A:HIS36 4.5 34.4 1.0 CD A:LYS243 4.7 38.2 1.0 C A:HIS36 4.7 32.1 1.0 N A:THR37 4.7 30.9 1.0 C A:ILE35 4.9 35.8 1.0

K.J.Waldron, S.J.Firbank, S.J.Dainty, M.Perez-Rama, S.Tottey, N.J.Robinson. Structure and Metal Loading of A Soluble Periplasm Cuproprotein. J.Biol.Chem. V. 285 32504 2010.
ISSN: ISSN 0021-9258
PubMed: 20702411
DOI: 10.1074/JBC.M110.153080