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Atomistry » Copper » PDB 2vr7-2xv0 » 2wz6 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Copper » PDB 2vr7-2xv0 » 2wz6 » |
Copper in PDB 2wz6: G93A SOD1 Mutant Complexed with Quinazoline.Enzymatic activity of G93A SOD1 Mutant Complexed with Quinazoline.
All present enzymatic activity of G93A SOD1 Mutant Complexed with Quinazoline.:
1.15.1.1; Protein crystallography data
The structure of G93A SOD1 Mutant Complexed with Quinazoline., PDB code: 2wz6
was solved by
S.V.Antonyuk,
R.W.Strange,
S.S.Hasnain,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2wz6:
The structure of G93A SOD1 Mutant Complexed with Quinazoline. also contains other interesting chemical elements:
Copper Binding Sites:
The binding sites of Copper atom in the G93A SOD1 Mutant Complexed with Quinazoline.
(pdb code 2wz6). This binding sites where shown within
5.0 Angstroms radius around Copper atom.
In total 2 binding sites of Copper where determined in the G93A SOD1 Mutant Complexed with Quinazoline., PDB code: 2wz6: Jump to Copper binding site number: 1; 2; Copper binding site 1 out of 2 in 2wz6Go back to Copper Binding Sites List in 2wz6
Copper binding site 1 out
of 2 in the G93A SOD1 Mutant Complexed with Quinazoline.
Mono view Stereo pair view
Copper binding site 2 out of 2 in 2wz6Go back to Copper Binding Sites List in 2wz6
Copper binding site 2 out
of 2 in the G93A SOD1 Mutant Complexed with Quinazoline.
Mono view Stereo pair view
Reference:
S.Antonyuk,
R.W.Strange,
S.S.Hasnain.
Structural Discovery of Small Molecule Binding Sites in Cu-Zn Human Superoxide Dismutase Familial Amyotrophic Lateral Sclerosis Mutants Provides Insights For Lead Optimization. J.Med.Chem. V. 53 1402 2010.
Page generated: Wed Jul 31 00:08:48 2024
ISSN: ISSN 0022-2623 PubMed: 20067275 DOI: 10.1021/JM9017948 |
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