Atomistry » Copper » PDB 2pp8-2vr6 » 2r27
Atomistry »
  Copper »
    PDB 2pp8-2vr6 »
      2r27 »

Copper in PDB 2r27: Constitutively Zinc-Deficient Mutant of Human Superoxide Dismutase (Sod), C6A, H80S, H83S, C111S

Enzymatic activity of Constitutively Zinc-Deficient Mutant of Human Superoxide Dismutase (Sod), C6A, H80S, H83S, C111S

All present enzymatic activity of Constitutively Zinc-Deficient Mutant of Human Superoxide Dismutase (Sod), C6A, H80S, H83S, C111S:
1.15.1.1;

Protein crystallography data

The structure of Constitutively Zinc-Deficient Mutant of Human Superoxide Dismutase (Sod), C6A, H80S, H83S, C111S, PDB code: 2r27 was solved by B.R.Roberts, E.D.Getzoff, P.A.Karplus, J.S.Beckman, J.A.Tainer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.20 / 2.00
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 107.200, 35.900, 68.300, 90.00, 104.80, 90.00
R / Rfree (%) 18.4 / 24.6

Copper Binding Sites:

The binding sites of Copper atom in the Constitutively Zinc-Deficient Mutant of Human Superoxide Dismutase (Sod), C6A, H80S, H83S, C111S (pdb code 2r27). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 3 binding sites of Copper where determined in the Constitutively Zinc-Deficient Mutant of Human Superoxide Dismutase (Sod), C6A, H80S, H83S, C111S, PDB code: 2r27:
Jump to Copper binding site number: 1; 2; 3;

Copper binding site 1 out of 3 in 2r27

Go back to Copper Binding Sites List in 2r27
Copper binding site 1 out of 3 in the Constitutively Zinc-Deficient Mutant of Human Superoxide Dismutase (Sod), C6A, H80S, H83S, C111S


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Constitutively Zinc-Deficient Mutant of Human Superoxide Dismutase (Sod), C6A, H80S, H83S, C111S within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cu154

b:29.8
occ:0.83
CU A:CU154 0.0 29.8 0.8
CU A:CU154 1.3 31.3 0.2
NE2 A:HIS48 1.9 30.4 1.0
NE2 A:HIS120 2.2 26.1 1.0
ND1 A:HIS46 2.2 27.4 1.0
NE2 A:HIS63 2.4 35.8 1.0
O A:HOH223 2.7 44.9 1.0
CE1 A:HIS48 2.8 28.8 1.0
CD2 A:HIS48 3.0 20.6 1.0
CD2 A:HIS63 3.1 33.0 1.0
CE1 A:HIS120 3.1 24.2 1.0
CG A:HIS46 3.1 27.6 1.0
CD2 A:HIS120 3.2 23.5 1.0
CE1 A:HIS46 3.2 31.2 1.0
CB A:HIS46 3.4 22.8 1.0
CE1 A:HIS63 3.6 37.6 1.0
ND1 A:HIS48 4.0 26.4 1.0
CG A:HIS48 4.1 22.7 1.0
ND1 A:HIS120 4.2 24.3 1.0
CG A:HIS120 4.2 25.7 1.0
CD2 A:HIS46 4.3 31.3 1.0
NE2 A:HIS46 4.3 27.9 1.0
CG A:HIS63 4.3 32.3 1.0
ND1 A:HIS63 4.5 33.3 1.0
CA A:HIS46 4.6 22.9 1.0
CB A:VAL118 4.6 22.4 1.0
O A:HOH160 4.7 27.9 1.0
CG1 A:VAL118 4.7 22.3 1.0
N A:HIS46 4.7 26.6 1.0

Copper binding site 2 out of 3 in 2r27

Go back to Copper Binding Sites List in 2r27
Copper binding site 2 out of 3 in the Constitutively Zinc-Deficient Mutant of Human Superoxide Dismutase (Sod), C6A, H80S, H83S, C111S


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Constitutively Zinc-Deficient Mutant of Human Superoxide Dismutase (Sod), C6A, H80S, H83S, C111S within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cu154

b:31.3
occ:0.17
CU A:CU154 0.0 31.3 0.2
CU A:CU154 1.3 29.8 0.8
NE2 A:HIS120 2.2 26.1 1.0
NE2 A:HIS48 2.2 30.4 1.0
ND1 A:HIS46 2.5 27.4 1.0
CD2 A:HIS48 2.8 20.6 1.0
CD2 A:HIS120 2.8 23.5 1.0
CB A:HIS46 3.0 22.8 1.0
CG A:HIS46 3.0 27.6 1.0
CE1 A:HIS120 3.3 24.2 1.0
CE1 A:HIS48 3.4 28.8 1.0
NE2 A:HIS63 3.5 35.8 1.0
CB A:VAL118 3.5 22.4 1.0
CE1 A:HIS46 3.6 31.2 1.0
N A:HIS46 3.7 26.6 1.0
CG1 A:VAL118 3.8 22.3 1.0
CA A:HIS46 3.8 22.9 1.0
O A:HOH223 4.0 44.9 1.0
CD2 A:HIS63 4.0 33.0 1.0
O A:HIS46 4.1 22.7 1.0
CG A:HIS48 4.1 22.7 1.0
CG A:HIS120 4.1 25.7 1.0
O A:VAL118 4.1 21.4 1.0
C A:HIS46 4.1 26.8 1.0
ND1 A:HIS48 4.3 26.4 1.0
ND1 A:HIS120 4.3 24.3 1.0
CD2 A:HIS46 4.3 31.3 1.0
CG2 A:VAL118 4.3 21.0 1.0
C A:VAL118 4.5 19.3 1.0
NE2 A:HIS46 4.5 27.9 1.0
CE1 A:HIS63 4.6 37.6 1.0
CA A:VAL118 4.6 18.6 1.0
C A:PHE45 4.7 23.0 1.0

Copper binding site 3 out of 3 in 2r27

Go back to Copper Binding Sites List in 2r27
Copper binding site 3 out of 3 in the Constitutively Zinc-Deficient Mutant of Human Superoxide Dismutase (Sod), C6A, H80S, H83S, C111S


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 3 of Constitutively Zinc-Deficient Mutant of Human Superoxide Dismutase (Sod), C6A, H80S, H83S, C111S within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cu154

b:42.4
occ:1.00
NE2 B:HIS120 2.0 29.0 1.0
ND1 B:HIS46 2.1 33.6 1.0
NE2 B:HIS48 2.2 40.2 1.0
NE2 B:HIS63 2.5 61.3 1.0
O B:HOH234 2.8 52.8 1.0
CE1 B:HIS120 2.9 33.4 1.0
CE1 B:HIS46 3.0 37.5 1.0
CD2 B:HIS120 3.0 30.7 1.0
CG B:HIS46 3.1 35.2 1.0
CD2 B:HIS63 3.1 57.9 1.0
CE1 B:HIS48 3.1 34.4 1.0
CD2 B:HIS48 3.2 27.5 1.0
CB B:HIS46 3.4 32.7 1.0
CE1 B:HIS63 3.7 64.0 1.0
ND1 B:HIS120 4.0 29.9 1.0
CG B:HIS120 4.1 32.5 1.0
NE2 B:HIS46 4.1 34.9 1.0
CD2 B:HIS46 4.2 37.6 1.0
ND1 B:HIS48 4.2 36.0 1.0
CG B:HIS48 4.3 34.6 1.0
CG B:HIS63 4.3 54.7 1.0
ND1 B:HIS63 4.6 59.6 1.0
CA B:HIS46 4.6 28.7 1.0
CG1 B:VAL118 4.7 25.2 1.0
CB B:VAL118 4.7 26.5 1.0
N B:HIS46 4.8 25.6 1.0
O B:HOH193 4.9 53.0 1.0

Reference:

B.R.Roberts, J.A.Tainer, E.D.Getzoff, D.A.Malencik, S.R.Anderson, V.C.Bomben, K.R.Meyers, P.A.Karplus, J.S.Beckman. Structural Characterization of Zinc-Deficient Human Superoxide Dismutase and Implications For Als. J.Mol.Biol. V. 373 877 2007.
ISSN: ISSN 0022-2836
PubMed: 17888947
DOI: 10.1016/J.JMB.2007.07.043
Page generated: Sun Dec 13 11:06:55 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy