Copper in PDB 2jlp: Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase.
Enzymatic activity of Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase.
All present enzymatic activity of Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase.:
1.15.1.1;
Protein crystallography data
The structure of Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase., PDB code: 2jlp
was solved by
S.V.Antonyuk,
R.W.Strange,
S.L.Marklund,
S.S.Hasnain,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
28.20 /
1.70
|
Space group
|
P 1 21 1
|
Cell size a, b, c (Å), α, β, γ (°)
|
56.738,
93.588,
75.600,
90.00,
106.23,
90.00
|
R / Rfree (%)
|
15 /
18.5
|
Other elements in 2jlp:
The structure of Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase. also contains other interesting chemical elements:
Copper Binding Sites:
The binding sites of Copper atom in the Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase.
(pdb code 2jlp). This binding sites where shown within
5.0 Angstroms radius around Copper atom.
In total 8 binding sites of Copper where determined in the
Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase., PDB code: 2jlp:
Jump to Copper binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Copper binding site 1 out
of 8 in 2jlp
Go back to
Copper Binding Sites List in 2jlp
Copper binding site 1 out
of 8 in the Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase.
![](/pictures/CU/pdb/jl/2jlp-CU-sphere_01.jpg) Mono view
![](/pictures/CU/pdb/jl/2jlp-CU-sphere_01_stereo.jpg) Stereo pair view
|
A full contact list of Copper with other atoms in the Cu binding
site number 1 of Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Cu225
b:31.8
occ:0.70
|
CU
|
A:CU225
|
0.0
|
31.8
|
0.7
|
CU
|
A:CU225
|
1.2
|
32.5
|
0.3
|
NE2
|
A:HIS98
|
2.0
|
28.6
|
1.0
|
NE2
|
A:HIS163
|
2.1
|
29.3
|
1.0
|
ND1
|
A:HIS96
|
2.2
|
33.5
|
1.0
|
CD2
|
A:HIS163
|
2.9
|
29.7
|
1.0
|
CD2
|
A:HIS98
|
3.0
|
31.4
|
1.0
|
CE1
|
A:HIS98
|
3.0
|
29.8
|
1.0
|
CG
|
A:HIS96
|
3.0
|
28.3
|
1.0
|
CE1
|
A:HIS163
|
3.2
|
32.5
|
1.0
|
NE2
|
A:HIS113
|
3.2
|
34.0
|
1.0
|
CB
|
A:HIS96
|
3.2
|
30.6
|
1.0
|
CE1
|
A:HIS96
|
3.2
|
29.4
|
1.0
|
O
|
A:HOH2128
|
3.5
|
27.5
|
1.0
|
CD2
|
A:HIS113
|
3.7
|
30.7
|
1.0
|
CE1
|
A:HIS113
|
4.0
|
31.3
|
1.0
|
CB
|
A:VAL161
|
4.1
|
26.6
|
1.0
|
ND1
|
A:HIS98
|
4.1
|
27.5
|
1.0
|
CG
|
A:HIS163
|
4.1
|
26.9
|
1.0
|
CG
|
A:HIS98
|
4.1
|
26.6
|
1.0
|
N
|
A:HIS96
|
4.2
|
26.3
|
1.0
|
CA
|
A:HIS96
|
4.2
|
28.0
|
1.0
|
O
|
A:VAL161
|
4.2
|
26.5
|
1.0
|
ND1
|
A:HIS163
|
4.2
|
29.1
|
1.0
|
CD2
|
A:HIS96
|
4.2
|
31.2
|
1.0
|
NE2
|
A:HIS96
|
4.3
|
30.6
|
1.0
|
CG1
|
A:VAL161
|
4.3
|
27.3
|
1.0
|
O
|
A:HIS96
|
4.5
|
28.0
|
1.0
|
C
|
A:HIS96
|
4.6
|
27.8
|
1.0
|
CG
|
A:HIS113
|
4.8
|
27.9
|
1.0
|
C
|
A:VAL161
|
4.8
|
24.9
|
1.0
|
ND1
|
A:HIS113
|
4.9
|
27.5
|
1.0
|
CA
|
A:VAL161
|
5.0
|
26.6
|
1.0
|
|
Copper binding site 2 out
of 8 in 2jlp
Go back to
Copper Binding Sites List in 2jlp
Copper binding site 2 out
of 8 in the Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase.
![](/pictures/CU/pdb/jl/2jlp-CU-sphere_02.jpg) Mono view
![](/pictures/CU/pdb/jl/2jlp-CU-sphere_02_stereo.jpg) Stereo pair view
|
A full contact list of Copper with other atoms in the Cu binding
site number 2 of Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Cu225
b:32.5
occ:0.30
|
CU
|
A:CU225
|
0.0
|
32.5
|
0.3
|
CU
|
A:CU225
|
1.2
|
31.8
|
0.7
|
NE2
|
A:HIS113
|
2.3
|
34.0
|
1.0
|
NE2
|
A:HIS163
|
2.3
|
29.3
|
1.0
|
ND1
|
A:HIS96
|
2.3
|
33.5
|
1.0
|
NE2
|
A:HIS98
|
2.4
|
28.6
|
1.0
|
O
|
A:HOH2128
|
2.4
|
27.5
|
1.0
|
CE1
|
A:HIS98
|
2.9
|
29.8
|
1.0
|
CE1
|
A:HIS163
|
3.0
|
32.5
|
1.0
|
CD2
|
A:HIS113
|
3.0
|
30.7
|
1.0
|
CE1
|
A:HIS96
|
3.0
|
29.4
|
1.0
|
CE1
|
A:HIS113
|
3.3
|
31.3
|
1.0
|
CD2
|
A:HIS163
|
3.3
|
29.7
|
1.0
|
CG
|
A:HIS96
|
3.4
|
28.3
|
1.0
|
CD2
|
A:HIS98
|
3.6
|
31.4
|
1.0
|
CB
|
A:HIS96
|
3.8
|
30.6
|
1.0
|
ND1
|
A:HIS163
|
4.1
|
29.1
|
1.0
|
CG
|
A:HIS113
|
4.2
|
27.9
|
1.0
|
ND1
|
A:HIS98
|
4.2
|
27.5
|
1.0
|
NE2
|
A:HIS96
|
4.2
|
30.6
|
1.0
|
ND1
|
A:HIS113
|
4.2
|
27.5
|
1.0
|
CG
|
A:HIS163
|
4.3
|
26.9
|
1.0
|
CD2
|
A:HIS96
|
4.4
|
31.2
|
1.0
|
CG
|
A:HIS98
|
4.5
|
26.6
|
1.0
|
CB
|
A:ASN180
|
4.7
|
32.8
|
1.0
|
O
|
A:HOH2214
|
4.7
|
31.2
|
1.0
|
O
|
A:HOH2220
|
4.8
|
32.7
|
1.0
|
O
|
A:ASN180
|
4.9
|
30.9
|
1.0
|
|
Copper binding site 3 out
of 8 in 2jlp
Go back to
Copper Binding Sites List in 2jlp
Copper binding site 3 out
of 8 in the Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase.
![](/pictures/CU/pdb/jl/2jlp-CU-sphere_03.jpg) Mono view
![](/pictures/CU/pdb/jl/2jlp-CU-sphere_03_stereo.jpg) Stereo pair view
|
A full contact list of Copper with other atoms in the Cu binding
site number 3 of Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Cu225
b:30.4
occ:0.60
|
CU
|
B:CU225
|
0.0
|
30.4
|
0.6
|
CU
|
B:CU225
|
0.7
|
31.4
|
0.4
|
NE2
|
B:HIS163
|
2.0
|
24.9
|
1.0
|
NE2
|
B:HIS98
|
2.1
|
29.5
|
1.0
|
ND1
|
B:HIS96
|
2.1
|
28.9
|
1.0
|
CD2
|
B:HIS163
|
2.9
|
26.3
|
1.0
|
CG
|
B:HIS96
|
3.0
|
29.1
|
1.0
|
CE1
|
B:HIS98
|
3.0
|
27.9
|
1.0
|
CD2
|
B:HIS98
|
3.1
|
31.1
|
1.0
|
CE1
|
B:HIS163
|
3.1
|
27.8
|
1.0
|
CE1
|
B:HIS96
|
3.1
|
27.7
|
1.0
|
S
|
B:SCN227
|
3.1
|
32.6
|
0.5
|
CB
|
B:HIS96
|
3.2
|
28.9
|
1.0
|
NE2
|
B:HIS113
|
3.5
|
28.9
|
1.0
|
CB
|
B:VAL161
|
4.0
|
26.9
|
1.0
|
CD2
|
B:HIS113
|
4.1
|
28.7
|
1.0
|
CG
|
B:HIS163
|
4.1
|
26.3
|
1.0
|
ND1
|
B:HIS163
|
4.1
|
26.3
|
1.0
|
ND1
|
B:HIS98
|
4.2
|
27.7
|
1.0
|
CG1
|
B:VAL161
|
4.2
|
26.3
|
1.0
|
CD2
|
B:HIS96
|
4.2
|
29.1
|
1.0
|
NE2
|
B:HIS96
|
4.2
|
28.0
|
1.0
|
CG
|
B:HIS98
|
4.2
|
27.8
|
1.0
|
O
|
B:VAL161
|
4.3
|
26.6
|
1.0
|
CA
|
B:HIS96
|
4.3
|
27.1
|
1.0
|
N
|
B:HIS96
|
4.3
|
26.6
|
1.0
|
CE1
|
B:HIS113
|
4.4
|
28.2
|
1.0
|
C
|
B:HIS96
|
4.7
|
28.8
|
1.0
|
O
|
B:HIS96
|
4.7
|
28.4
|
1.0
|
C
|
B:SCN227
|
4.7
|
33.0
|
0.5
|
S
|
B:SCN227
|
4.8
|
48.9
|
0.5
|
C
|
B:VAL161
|
4.8
|
26.5
|
1.0
|
CG2
|
B:VAL161
|
5.0
|
27.9
|
1.0
|
O
|
B:HOH2195
|
5.0
|
28.0
|
1.0
|
|
Copper binding site 4 out
of 8 in 2jlp
Go back to
Copper Binding Sites List in 2jlp
Copper binding site 4 out
of 8 in the Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase.
![](/pictures/CU/pdb/jl/2jlp-CU-sphere_04.jpg) Mono view
![](/pictures/CU/pdb/jl/2jlp-CU-sphere_04_stereo.jpg) Stereo pair view
|
A full contact list of Copper with other atoms in the Cu binding
site number 4 of Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Cu225
b:31.4
occ:0.40
|
CU
|
B:CU225
|
0.0
|
31.4
|
0.4
|
CU
|
B:CU225
|
0.7
|
30.4
|
0.6
|
NE2
|
B:HIS163
|
2.0
|
24.9
|
1.0
|
NE2
|
B:HIS98
|
2.1
|
29.5
|
1.0
|
ND1
|
B:HIS96
|
2.3
|
28.9
|
1.0
|
S
|
B:SCN227
|
2.4
|
32.6
|
0.5
|
CE1
|
B:HIS98
|
2.8
|
27.9
|
1.0
|
CE1
|
B:HIS163
|
2.8
|
27.8
|
1.0
|
NE2
|
B:HIS113
|
3.1
|
28.9
|
1.0
|
CE1
|
B:HIS96
|
3.1
|
27.7
|
1.0
|
CD2
|
B:HIS163
|
3.2
|
26.3
|
1.0
|
CD2
|
B:HIS98
|
3.3
|
31.1
|
1.0
|
CG
|
B:HIS96
|
3.4
|
29.1
|
1.0
|
CD2
|
B:HIS113
|
3.7
|
28.7
|
1.0
|
CB
|
B:HIS96
|
3.7
|
28.9
|
1.0
|
ND1
|
B:HIS98
|
4.0
|
27.7
|
1.0
|
ND1
|
B:HIS163
|
4.0
|
26.3
|
1.0
|
C
|
B:SCN227
|
4.0
|
33.0
|
0.5
|
S
|
B:SCN227
|
4.0
|
48.9
|
0.5
|
CE1
|
B:HIS113
|
4.1
|
28.2
|
1.0
|
CG
|
B:HIS163
|
4.2
|
26.3
|
1.0
|
CG
|
B:HIS98
|
4.2
|
27.8
|
1.0
|
NE2
|
B:HIS96
|
4.3
|
28.0
|
1.0
|
O
|
B:HOH2195
|
4.4
|
28.0
|
1.0
|
CD2
|
B:HIS96
|
4.4
|
29.1
|
1.0
|
CB
|
B:VAL161
|
4.5
|
26.9
|
1.0
|
CG1
|
B:VAL161
|
4.5
|
26.3
|
1.0
|
CG
|
B:HIS113
|
4.9
|
22.5
|
1.0
|
CA
|
B:HIS96
|
4.9
|
27.1
|
1.0
|
C
|
B:SCN227
|
4.9
|
47.1
|
0.5
|
O
|
B:VAL161
|
5.0
|
26.6
|
1.0
|
N
|
B:HIS96
|
5.0
|
26.6
|
1.0
|
|
Copper binding site 5 out
of 8 in 2jlp
Go back to
Copper Binding Sites List in 2jlp
Copper binding site 5 out
of 8 in the Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase.
![](/pictures/CU/pdb/jl/2jlp-CU-sphere_05.jpg) Mono view
![](/pictures/CU/pdb/jl/2jlp-CU-sphere_05_stereo.jpg) Stereo pair view
|
A full contact list of Copper with other atoms in the Cu binding
site number 5 of Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Cu225
b:28.3
occ:0.55
|
CU
|
C:CU225
|
0.0
|
28.3
|
0.6
|
CU
|
C:CU225
|
0.8
|
31.9
|
0.5
|
NE2
|
C:HIS163
|
2.0
|
26.1
|
1.0
|
ND1
|
C:HIS96
|
2.0
|
29.6
|
1.0
|
NE2
|
C:HIS98
|
2.0
|
27.8
|
1.0
|
CD2
|
C:HIS163
|
2.9
|
25.7
|
1.0
|
CG
|
C:HIS96
|
2.9
|
30.1
|
1.0
|
CD2
|
C:HIS98
|
3.0
|
27.4
|
1.0
|
CE1
|
C:HIS98
|
3.1
|
29.3
|
1.0
|
CE1
|
C:HIS163
|
3.1
|
27.2
|
1.0
|
CE1
|
C:HIS96
|
3.1
|
29.8
|
1.0
|
S
|
C:SCN227
|
3.1
|
31.4
|
0.5
|
CB
|
C:HIS96
|
3.2
|
29.8
|
1.0
|
NE2
|
C:HIS113
|
3.6
|
27.3
|
1.0
|
CB
|
C:VAL161
|
4.0
|
27.9
|
1.0
|
CG
|
C:HIS163
|
4.1
|
25.3
|
1.0
|
ND1
|
C:HIS163
|
4.1
|
24.6
|
1.0
|
CD2
|
C:HIS96
|
4.1
|
29.2
|
1.0
|
CD2
|
C:HIS113
|
4.1
|
27.3
|
1.0
|
ND1
|
C:HIS98
|
4.2
|
30.1
|
1.0
|
CG
|
C:HIS98
|
4.2
|
27.4
|
1.0
|
NE2
|
C:HIS96
|
4.2
|
30.1
|
1.0
|
CG1
|
C:VAL161
|
4.2
|
27.2
|
1.0
|
O
|
C:VAL161
|
4.2
|
26.9
|
1.0
|
CA
|
C:HIS96
|
4.3
|
27.6
|
1.0
|
N
|
C:HIS96
|
4.3
|
27.1
|
1.0
|
CE1
|
C:HIS113
|
4.4
|
26.9
|
1.0
|
S
|
C:SCN227
|
4.5
|
48.9
|
0.5
|
C
|
C:SCN227
|
4.7
|
31.4
|
0.5
|
O
|
C:HIS96
|
4.7
|
27.5
|
1.0
|
C
|
C:HIS96
|
4.8
|
27.7
|
1.0
|
C
|
C:VAL161
|
4.8
|
26.5
|
1.0
|
O
|
C:HOH2193
|
4.9
|
28.9
|
1.0
|
CA
|
C:VAL161
|
4.9
|
26.4
|
1.0
|
CG2
|
C:VAL161
|
5.0
|
27.3
|
1.0
|
|
Copper binding site 6 out
of 8 in 2jlp
Go back to
Copper Binding Sites List in 2jlp
Copper binding site 6 out
of 8 in the Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase.
![](/pictures/CU/pdb/jl/2jlp-CU-sphere_06.jpg) Mono view
![](/pictures/CU/pdb/jl/2jlp-CU-sphere_06_stereo.jpg) Stereo pair view
|
A full contact list of Copper with other atoms in the Cu binding
site number 6 of Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Cu225
b:31.9
occ:0.45
|
CU
|
C:CU225
|
0.0
|
31.9
|
0.5
|
CU
|
C:CU225
|
0.8
|
28.3
|
0.6
|
NE2
|
C:HIS98
|
2.0
|
27.8
|
1.0
|
NE2
|
C:HIS163
|
2.0
|
26.1
|
1.0
|
ND1
|
C:HIS96
|
2.3
|
29.6
|
1.0
|
S
|
C:SCN227
|
2.3
|
31.4
|
0.5
|
CE1
|
C:HIS98
|
2.7
|
29.3
|
1.0
|
CE1
|
C:HIS163
|
2.8
|
27.2
|
1.0
|
NE2
|
C:HIS113
|
3.1
|
27.3
|
1.0
|
CE1
|
C:HIS96
|
3.2
|
29.8
|
1.0
|
CD2
|
C:HIS163
|
3.2
|
25.7
|
1.0
|
CD2
|
C:HIS98
|
3.2
|
27.4
|
1.0
|
CG
|
C:HIS96
|
3.3
|
30.1
|
1.0
|
CB
|
C:HIS96
|
3.7
|
29.8
|
1.0
|
S
|
C:SCN227
|
3.7
|
48.9
|
0.5
|
CD2
|
C:HIS113
|
3.7
|
27.3
|
1.0
|
C
|
C:SCN227
|
3.9
|
31.4
|
0.5
|
ND1
|
C:HIS98
|
3.9
|
30.1
|
1.0
|
ND1
|
C:HIS163
|
4.0
|
24.6
|
1.0
|
CE1
|
C:HIS113
|
4.1
|
26.9
|
1.0
|
CG
|
C:HIS98
|
4.2
|
27.4
|
1.0
|
CG
|
C:HIS163
|
4.2
|
25.3
|
1.0
|
NE2
|
C:HIS96
|
4.3
|
30.1
|
1.0
|
O
|
C:HOH2193
|
4.3
|
28.9
|
1.0
|
CD2
|
C:HIS96
|
4.4
|
29.2
|
1.0
|
CB
|
C:VAL161
|
4.5
|
27.9
|
1.0
|
CG1
|
C:VAL161
|
4.6
|
27.2
|
1.0
|
C
|
C:SCN227
|
4.6
|
47.6
|
0.5
|
CG
|
C:HIS113
|
4.9
|
25.3
|
1.0
|
CA
|
C:HIS96
|
4.9
|
27.6
|
1.0
|
O
|
C:VAL161
|
5.0
|
26.9
|
1.0
|
N
|
C:SCN227
|
5.0
|
30.7
|
0.5
|
|
Copper binding site 7 out
of 8 in 2jlp
Go back to
Copper Binding Sites List in 2jlp
Copper binding site 7 out
of 8 in the Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase.
![](/pictures/CU/pdb/jl/2jlp-CU-sphere_07.jpg) Mono view
![](/pictures/CU/pdb/jl/2jlp-CU-sphere_07_stereo.jpg) Stereo pair view
|
A full contact list of Copper with other atoms in the Cu binding
site number 7 of Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Cu225
b:31.6
occ:0.60
|
CU
|
D:CU225
|
0.0
|
31.6
|
0.6
|
CU
|
D:CU225
|
1.2
|
30.4
|
0.4
|
ND1
|
D:HIS96
|
2.0
|
31.8
|
1.0
|
NE2
|
D:HIS163
|
2.1
|
28.6
|
1.0
|
NE2
|
D:HIS98
|
2.1
|
27.4
|
1.0
|
CD2
|
D:HIS163
|
2.9
|
31.5
|
1.0
|
CG
|
D:HIS96
|
2.9
|
27.6
|
1.0
|
CD2
|
D:HIS98
|
3.0
|
29.4
|
1.0
|
CB
|
D:HIS96
|
3.1
|
29.5
|
1.0
|
CE1
|
D:HIS96
|
3.1
|
31.7
|
1.0
|
CE1
|
D:HIS98
|
3.2
|
28.8
|
1.0
|
CE1
|
D:HIS163
|
3.2
|
30.7
|
1.0
|
NE2
|
D:HIS113
|
3.3
|
34.2
|
1.0
|
O
|
D:HOH2114
|
3.7
|
35.2
|
1.0
|
CD2
|
D:HIS113
|
3.9
|
33.7
|
1.0
|
N
|
D:HIS96
|
4.0
|
26.1
|
1.0
|
CA
|
D:HIS96
|
4.1
|
27.9
|
1.0
|
CD2
|
D:HIS96
|
4.1
|
30.6
|
1.0
|
O
|
D:VAL161
|
4.1
|
27.9
|
1.0
|
CB
|
D:VAL161
|
4.1
|
26.4
|
1.0
|
CG
|
D:HIS163
|
4.1
|
26.0
|
1.0
|
CE1
|
D:HIS113
|
4.1
|
34.7
|
1.0
|
NE2
|
D:HIS96
|
4.2
|
27.5
|
1.0
|
CG
|
D:HIS98
|
4.2
|
26.0
|
1.0
|
ND1
|
D:HIS163
|
4.3
|
26.6
|
1.0
|
ND1
|
D:HIS98
|
4.3
|
28.2
|
1.0
|
CG1
|
D:VAL161
|
4.4
|
25.7
|
1.0
|
O
|
D:HIS96
|
4.5
|
28.2
|
1.0
|
C
|
D:HIS96
|
4.5
|
28.0
|
1.0
|
C
|
D:VAL161
|
4.7
|
25.3
|
1.0
|
CG
|
D:HIS113
|
4.9
|
28.6
|
1.0
|
CA
|
D:VAL161
|
4.9
|
25.8
|
1.0
|
C
|
D:ILE95
|
5.0
|
26.0
|
1.0
|
|
Copper binding site 8 out
of 8 in 2jlp
Go back to
Copper Binding Sites List in 2jlp
Copper binding site 8 out
of 8 in the Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase.
![](/pictures/CU/pdb/jl/2jlp-CU-sphere_08.jpg) Mono view
![](/pictures/CU/pdb/jl/2jlp-CU-sphere_08_stereo.jpg) Stereo pair view
|
A full contact list of Copper with other atoms in the Cu binding
site number 8 of Crystal Structure of Human Extracellular Copper-Zinc Superoxide Dismutase. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Cu225
b:30.4
occ:0.40
|
CU
|
D:CU225
|
0.0
|
30.4
|
0.4
|
CU
|
D:CU225
|
1.2
|
31.6
|
0.6
|
NE2
|
D:HIS98
|
2.1
|
27.4
|
1.0
|
NE2
|
D:HIS163
|
2.3
|
28.6
|
1.0
|
ND1
|
D:HIS96
|
2.4
|
31.8
|
1.0
|
NE2
|
D:HIS113
|
2.5
|
34.2
|
1.0
|
O
|
D:HOH2114
|
2.6
|
35.2
|
1.0
|
CE1
|
D:HIS98
|
2.7
|
28.8
|
1.0
|
CE1
|
D:HIS163
|
3.0
|
30.7
|
1.0
|
CD2
|
D:HIS113
|
3.2
|
33.7
|
1.0
|
CE1
|
D:HIS96
|
3.2
|
31.7
|
1.0
|
CD2
|
D:HIS98
|
3.3
|
29.4
|
1.0
|
CD2
|
D:HIS163
|
3.4
|
31.5
|
1.0
|
CG
|
D:HIS96
|
3.5
|
27.6
|
1.0
|
CE1
|
D:HIS113
|
3.6
|
34.7
|
1.0
|
CB
|
D:HIS96
|
3.9
|
29.5
|
1.0
|
ND1
|
D:HIS98
|
3.9
|
28.2
|
1.0
|
ND1
|
D:HIS163
|
4.1
|
26.6
|
1.0
|
CG
|
D:HIS98
|
4.3
|
26.0
|
1.0
|
CG
|
D:HIS113
|
4.3
|
28.6
|
1.0
|
CG
|
D:HIS163
|
4.4
|
26.0
|
1.0
|
NE2
|
D:HIS96
|
4.4
|
27.5
|
1.0
|
ND1
|
D:HIS113
|
4.5
|
29.3
|
1.0
|
CD2
|
D:HIS96
|
4.5
|
30.6
|
1.0
|
O
|
D:HOH2194
|
4.8
|
52.6
|
1.0
|
O
|
D:HOH2187
|
4.8
|
38.9
|
1.0
|
CB
|
D:ASN180
|
4.9
|
33.6
|
1.0
|
CB
|
D:VAL161
|
4.9
|
26.4
|
1.0
|
O
|
D:HOH2192
|
4.9
|
30.1
|
1.0
|
CG1
|
D:VAL161
|
5.0
|
25.7
|
1.0
|
|
Reference:
S.V.Antonyuk,
R.W.Strange,
S.L.Marklund,
S.S.Hasnain.
The Structure of Human Extracellular Copper-Zinc Superoxide Dismutase at 1.7 A Resolution: Insights Into Heparin and Collagen Binding. J.Mol.Biol. V. 388 310 2009.
ISSN: ISSN 0022-2836
PubMed: 19289127
DOI: 10.1016/J.JMB.2009.03.026
Page generated: Sun Dec 13 11:05:34 2020
|