Chemical elements
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    Cuprous Compounds
    Complex Copper Compounds
    Cupric Compounds
    PDB 1a2v-1bxu
    PDB 1bxv-1fwx
    PDB 1g3d-1j9t
    PDB 1jcv-1mfm
    PDB 1mg2-1paz
    PDB 1pcs-1sii
    PDB 1sjm-1w6w
    PDB 1w77-2afn
    PDB 2ahk-2dv6
    PDB 2dws-2ggp
      2dws
      2dwt
      2dy2
      2dyr
      2dys
      2e2t
      2e2u
      2e2v
      2e46
      2e47
      2e86
      2eb8
      2eb9
      2eib
      2eic
      2eid
      2eie
      2eij
      2eik
      2eil
      2eim
      2ein
      2eiq
      2eir
      2fjs
      2fk1
      2fk2
      2fk3
      2fnw
      2fos
      2fou
      2fov
      2foy
      2fqd
      2fqe
      2fqf
      2fqg
      2ft6
      2ft7
      2ft8
      2fta
      2fu7
      2fwl
      2ga7
      2gb2
      2gba
      2gbt
      2gbv
      2gc4
      2ggp
    PDB 2ghz-2mta
    PDB 2nrd-2vm3
    PDB 2vm4-2yah
    PDB 2yam-3bkt
    PDB 3bqv-3fyi
    PDB 3g5w-3mie
    PDB 3mif-3t6v
    PDB 3t6w-9pcy

Copper in the structure of Human Carbonic Anhydrase II Complexed With Two-Prong Inhibitors (pdb 2fov)






The binding sites of Copper atom in the structure of Human Carbonic Anhydrase II Complexed With Two-Prong Inhibitors (pdb code 2fov). This binding sites where shown with 5.0 Angstroms radius around Copper atom.
The 2fov structure was solved by K.M.JUDE, D.W.CHRISTIANSON, with X-Ray Crystallography technique, brief refinement statistics is given in the table below:
Resolution (A)50.0-1.1
Space groupP1211
a (A)42.362
b (A)41.482
c (A)72.234
alpha (°)90.00
beta (°)104.34
gamma (°)90.00
Rfactor (%)14.3
Rfree (%)18.7


Copper Binding Sites:

Copper binding site 1 out of 3 in 2fov


Copper binding site 1 out of 3 in 2fov
Click to enlarge
stereopicture of Copper binding site 1 out of 3 in 2fov
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Copper in the PDB 2fov. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: A: Ser2, A: His3, A: Hoh568,

conact list:


AtomAtomDistance (A)
CuO A:Ser24.03
CuN A:Ser24.10
CuCB A:Ser22.65
CuCB A:Ser22.49
CuOG A:Ser23.52
CuOG A:Ser22.84
CuC A:Ser22.80
CuCA A:Ser22.66
CuO A:His33.68
CuNE2 A:His34.00
CuN A:His32.24
CuCB A:His33.54
CuND1 A:His31.95
CuCD2 A:His34.07
CuC A:His34.04
CuCE1 A:His32.84
CuCG A:His33.01
CuCA A:His33.36
CuO A:Hoh5683.84

interactive model:


Copper binding site 2 out of 3 in 2fov


Copper binding site 2 out of 3 in 2fov
Click to enlarge
stereopicture of Copper binding site 2 out of 3 in 2fov
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Copper in the PDB 2fov. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: A: Trp5, A: Asn62, A: His64, A: Thr200, A: Pro201, A: B30301, A: Hoh451, A: Hoh482, A: Hoh535, A: Hoh609,

conact list:


AtomAtomDistance (A)
CuCZ2 A:Trp54.61
CuND2 A:Asn624.10
CuCG A:Asn624.64
CuNE2 A:His642.02
CuND1 A:His644.04
CuCD2 A:His643.11
CuCD2 A:His644.18
CuCE1 A:His642.91
CuCG A:His644.20
CuCG A:His644.91
CuOG1 A:Thr2004.54
CuO A:Pro2014.90
CuC9 A:B303013.77
CuC12 A:B303012.66
CuOXA A:B303013.90
CuN8 A:B303013.90
CuC14 A:B303012.21
CuC7 A:B303014.79
CuOXD A:B303013.54
CuC13 A:B303012.69
CuC10 A:B303012.63
CuN11 A:B303012.04
CuOXB A:B303011.97
CuC15 A:B303012.35
CuCU A:B303010.00
CuOXC A:B303011.95
CuO A:Hoh4514.83
CuO A:Hoh4824.42
CuO A:Hoh5354.86
CuO A:Hoh6092.51

interactive model:


Copper binding site 3 out of 3 in 2fov


Copper binding site 3 out of 3 in 2fov
Click to enlarge
stereopicture of Copper binding site 3 out of 3 in 2fov
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 3 of Copper in the PDB 2fov. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: A: His4, A: B30303, A: Hoh421, A: Hoh664,

conact list:


AtomAtomDistance (A)
CuNE2 A:His43.04
CuND1 A:His44.69
CuND1 A:His44.86
CuCD2 A:His43.29
CuCE1 A:His44.59
CuCE1 A:His44.15
CuCG A:His44.47
CuC9 A:B303034.19
CuC12 A:B303031.90
CuOXA A:B303032.99
CuC14 A:B303032.94
CuOXD A:B303034.10
CuC13 A:B303031.98
CuC10 A:B303032.68
CuN11 A:B303032.06
CuOXB A:B303031.96
CuC15 A:B303032.88
CuCU A:B303030.00
CuOXC A:B303031.97
CuO A:Hoh4214.49
CuO A:Hoh6643.36

interactive model:




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