Copper in the structure of Product Schiff-Base Intermediate of Copper Amine Oxidase From Arthrobacter Globiformis (pdb 2cwv)

The binding sites of Copper atom in the structure of Product Schiff-Base Intermediate of Copper Amine Oxidase From Arthrobacter Globiformis (pdb code 2cwv). This binding sites where shown with 5.0 Angstroms radius around Copper atom. The 2cwv structure was solved by Y.C.CHIU, T.OKAJIMA, T.MURAKAWA, M.UCHIDA, M.TAKI, S.HIROTA, M.KIM, H.YAMAGUCHI, Y.KAWANO, N.KAMIYA, S.KURODA, H.HAYASHI, Y.YAMAMOTO, K.TANIZAWA, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 40.0-1.9 Space group I121 a (A) 157.702 b (A) 62.849 c (A) 184.125 alpha (°) 90.00 beta (°) 112.43 gamma (°) 90.00 Rfactor (%) 20.1 Rfree (%) 23.1 Copper Binding Sites: Copper binding site 1 out of 2 in 2cwv Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Copper in the PDB 2cwv. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: 2ty382, A: His431, A: His433, A: His592, A: Met602, A: Hoh1074, A: Hoh1119, A: Hoh1121, A: Hoh1281, A: Hoh1342, conact list: Atom Atom Distance (A) Cu OX1 A:2ty382 4.64 Cu NE2 A:His431 2.11 Cu ND1 A:His431 4.17 Cu CD2 A:His431 3.10 Cu CE1 A:His431 3.06 Cu CG A:His431 4.22 Cu NE2 A:His433 2.12 Cu ND1 A:His433 4.25 Cu CD2 A:His433 2.89 Cu CE1 A:His433 3.25 Cu CG A:His433 4.12 Cu NE2 A:His592 4.30 Cu CB A:His592 3.33 Cu ND1 A:His592 2.19 Cu CD2 A:His592 4.28 Cu CE1 A:His592 3.21 Cu CG A:His592 3.11 Cu CA A:His592 4.87 Cu SD A:Met602 4.93 Cu O A:Hoh1074 4.31 Cu O A:Hoh1119 2.38 Cu O A:Hoh1121 4.24 Cu O A:Hoh1281 3.75 Cu O A:Hoh1342 2.26 interactive model: Copper binding site 2 out of 2 in 2cwv Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Copper in the PDB 2cwv. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: B: 2ty382, B: His431, B: His433, B: His592, B: Met602, B: Hoh1157, B: Hoh1289, B: Hoh1303, B: Hoh1533, conact list: Atom Atom Distance (A) Cu OX1 B:2ty382 4.72 Cu NE2 B:His431 2.12 Cu ND1 B:His431 4.19 Cu CD2 B:His431 3.08 Cu CE1 B:His431 3.09 Cu CG B:His431 4.21 Cu NE2 B:His433 2.18 Cu ND1 B:His433 4.31 Cu CD2 B:His433 2.92 Cu CE1 B:His433 3.32 Cu CG B:His433 4.16 Cu NE2 B:His592 4.28 Cu CB B:His592 3.34 Cu ND1 B:His592 2.18 Cu CD2 B:His592 4.27 Cu CE1 B:His592 3.19 Cu CG B:His592 3.11 Cu CA B:His592 4.88 Cu CE B:Met602 4.96 Cu SD B:Met602 4.84 Cu O B:Hoh1157 4.44 Cu O B:Hoh1289 2.57 Cu O B:Hoh1303 4.59 Cu O B:Hoh1533 4.78 interactive model: