Copper in PDB 2b7j: Crystal Structure of Yeast SCO1 with Copper Bound

The structure of Crystal Structure of Yeast SCO1 with Copper Bound, PDB code: 2b7j was solved by C.Abajian, A.C.Rosenzweig, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	81.65 / 2.30
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	55.600, 81.900, 79.300, 90.00, 90.00, 90.00
R / Rfree (%)	21 / 25.2

The binding sites of Copper atom in the Crystal Structure of Yeast SCO1 with Copper Bound (pdb code 2b7j). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 6 binding sites of Copper where determined in the Crystal Structure of Yeast SCO1 with Copper Bound, PDB code: 2b7j:
Jump to Copper binding site number: 1; 2; 3; 4; 5; 6;

Copper binding site 1 out of 6 in the Crystal Structure of Yeast SCO1 with Copper Bound


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Crystal Structure of Yeast SCO1 with Copper Bound within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu296 b:37.8 occ:0.51 SG A:CYS181 2.2 51.7 1.0 SG A:CYS216 2.4 54.6 1.0 CU A:CU297 2.7 37.8 0.3 CB A:CYS181 2.9 51.7 1.0 CU A:CU298 2.9 37.8 0.3 CB A:CYS216 3.2 54.6 1.0 CA A:CYS181 3.6 34.6 1.0 CD1 A:PHE143 4.1 23.0 1.0 CE1 A:HIS239 4.1 94.2 1.0 CG1 A:VAL221 4.2 43.0 1.0 CA A:CYS216 4.3 35.1 1.0 O A:VAL221 4.4 49.9 1.0 CB A:VAL221 4.5 43.0 1.0 NE2 A:HIS239 4.5 94.2 1.0 N A:CYS181 4.6 34.6 1.0 C A:CYS181 4.7 34.6 1.0 CE1 A:PHE143 4.7 23.0 1.0 O A:THR180 4.7 37.0 1.0 O A:CYS181 4.7 34.6 1.0 CG A:PHE143 4.8 23.0 1.0 CB A:PHE143 4.9 23.0 1.0 C A:THR180 5.0 37.0 1.0

Copper binding site 2 out of 6 in the Crystal Structure of Yeast SCO1 with Copper Bound


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Crystal Structure of Yeast SCO1 with Copper Bound within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu297 b:37.8 occ:0.32 NE2 A:HIS239 2.1 94.2 1.0 SG A:CYS181 2.2 51.7 1.0 CE1 A:HIS239 2.2 94.2 1.0 CU A:CU296 2.7 37.8 0.5 CB A:CYS181 2.8 51.7 1.0 CD2 A:HIS239 3.4 94.2 1.0 ND1 A:HIS239 3.5 94.2 1.0 CG1 A:VAL221 4.0 43.0 1.0 CG A:HIS239 4.1 94.2 1.0 CA A:CYS181 4.3 34.6 1.0 CU A:CU298 4.3 37.8 0.3 O A:VAL221 4.7 49.9 1.0 CB A:PHE143 4.7 23.0 1.0 OG A:SER240 4.8 48.3 1.0 N A:GLY144 4.9 29.8 1.0

Copper binding site 3 out of 6 in the Crystal Structure of Yeast SCO1 with Copper Bound


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 3 of Crystal Structure of Yeast SCO1 with Copper Bound within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu298 b:37.8 occ:0.30 CU A:CU296 2.9 37.8 0.5 CB A:CYS216 3.6 54.6 1.0 SG A:CYS216 3.7 54.6 1.0 O A:VAL221 4.1 49.9 1.0 CU A:CU297 4.3 37.8 0.3 C A:TYR222 4.4 62.5 1.0 CB A:CYS181 4.5 51.7 1.0 O A:CYS181 4.7 34.6 1.0 SG A:CYS181 4.8 51.7 1.0 CE1 A:HIS239 4.9 94.2 1.0

Copper binding site 4 out of 6 in the Crystal Structure of Yeast SCO1 with Copper Bound


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 4 of Crystal Structure of Yeast SCO1 with Copper Bound within 5.0Å range: probe atom residue distance (Å) B Occ C:Cu296 b:37.8 occ:0.31 NE2 C:HIS239 2.1 0.3 1.0 SG C:CYS181 2.1 64.5 1.0 CE1 C:HIS239 2.2 0.3 1.0 CU C:CU297 2.6 37.8 0.5 CB C:CYS181 2.8 64.5 1.0 CD2 C:HIS239 3.4 0.3 1.0 ND1 C:HIS239 3.5 0.3 1.0 CG1 C:VAL221 3.9 45.7 1.0 CG C:HIS239 4.1 0.3 1.0 CA C:CYS181 4.3 37.0 1.0 CU C:CU298 4.6 37.8 0.3 O C:VAL221 4.6 61.3 1.0 CB C:PHE143 4.6 18.9 1.0 OG C:SER240 4.8 48.1 1.0 N C:GLY144 4.9 29.0 1.0 SG C:CYS216 5.0 57.8 1.0 CB C:VAL221 5.0 45.7 1.0

Copper binding site 5 out of 6 in the Crystal Structure of Yeast SCO1 with Copper Bound


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 5 of Crystal Structure of Yeast SCO1 with Copper Bound within 5.0Å range: probe atom residue distance (Å) B Occ C:Cu297 b:37.8 occ:0.48 SG C:CYS181 2.2 64.5 1.0 SG C:CYS216 2.3 57.8 1.0 CU C:CU296 2.6 37.8 0.3 CB C:CYS181 2.9 64.5 1.0 CU C:CU298 3.0 37.8 0.3 CB C:CYS216 3.2 57.8 1.0 CA C:CYS181 3.6 37.0 1.0 CD1 C:PHE143 4.0 18.9 1.0 CG1 C:VAL221 4.1 45.7 1.0 CE1 C:HIS239 4.2 0.3 1.0 CA C:CYS216 4.3 32.6 1.0 O C:VAL221 4.5 61.3 1.0 CB C:VAL221 4.5 45.7 1.0 NE2 C:HIS239 4.5 0.3 1.0 N C:CYS181 4.5 37.0 1.0 CE1 C:PHE143 4.6 18.9 1.0 O C:THR180 4.6 35.7 1.0 C C:CYS181 4.7 37.0 1.0 O C:CYS181 4.7 37.0 1.0 CG C:PHE143 4.7 18.9 1.0 CB C:PHE143 4.8 18.9 1.0 C C:THR180 4.9 35.7 1.0

Copper binding site 6 out of 6 in the Crystal Structure of Yeast SCO1 with Copper Bound


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 6 of Crystal Structure of Yeast SCO1 with Copper Bound within 5.0Å range: probe atom residue distance (Å) B Occ C:Cu298 b:37.8 occ:0.30 CU C:CU297 3.0 37.8 0.5 SG C:CYS216 3.4 57.8 1.0 CB C:CYS216 3.6 57.8 1.0 O C:CYS181 4.3 37.0 1.0 CB C:CYS181 4.4 64.5 1.0 CU C:CU296 4.6 37.8 0.3 O C:VAL221 4.7 61.3 1.0 CA C:CYS181 4.8 37.0 1.0 C C:TYR222 4.8 59.9 1.0 SG C:CYS181 4.8 64.5 1.0 C C:CYS181 5.0 37.0 1.0

C.Abajian, A.C.Rosenzweig. Crystal Structure of Yeast SCO1. J.Biol.Inorg.Chem. V. 11 459 2006.
ISSN: ISSN 0949-8257
PubMed: 16570183
DOI: 10.1007/S00775-006-0096-7