Copper in the structure of Crystal Structure of Mitomycin C-Binding Protein Complexed With Copper(II)-Bleomycin A2 (pdb 2a4w)

The binding sites of Copper atom in the structure of Crystal Structure of Mitomycin C-Binding Protein Complexed With Copper(II)-Bleomycin A2 (pdb code 2a4w). This binding sites where shown with 5.0 Angstroms radius around Copper atom. The 2a4w structure was solved by N.DANSHIITSOODOL, C.A.DE PINHO, Y.MATOBA, T.KUMAGAI, M.SUGIYAMA, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 10.0-1.5 Space group P1211 a (A) 44.390 b (A) 60.670 c (A) 48.240 alpha (°) 90.00 beta (°) 101.33 gamma (°) 90.00 Rfactor (%) 20.5 Rfree (%) 24.4 Copper Binding Sites: Copper binding site 1 out of 1 in 2a4w Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Copper in the PDB 2a4w. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Blm750, A: Hoh608, A: Hoh653, conact list: Atom Atom Distance (A) Cu C29 A:Blm750 2.93 Cu O56 A:Blm750 4.89 Cu C1 A:Blm750 3.48 Cu OH1 A:Blm750 3.49 Cu C8 A:Blm750 4.65 Cu NA A:Blm750 4.12 Cu C2 A:Blm750 3.01 Cu NH A:Blm750 2.05 Cu NJ A:Blm750 1.94 Cu O12 A:Blm750 4.11 Cu C12 A:Blm750 2.91 Cu NB A:Blm750 2.29 Cu C28 A:Blm750 4.00 Cu C30 A:Blm750 4.09 Cu NI A:Blm750 3.99 Cu NC A:Blm750 2.21 Cu O1 A:Blm750 3.93 Cu NE A:Blm750 3.99 Cu C6 A:Blm750 2.90 Cu C5 A:Blm750 4.39 Cu NG A:Blm750 1.92 Cu C10 A:Blm750 2.95 Cu C13 A:Blm750 3.11 Cu C27 A:Blm750 2.85 Cu C9 A:Blm750 4.14 Cu C14 A:Blm750 3.25 Cu C63 A:Blm750 4.89 Cu C7 A:Blm750 2.83 Cu C3 A:Blm750 2.93 Cu NK A:Blm750 3.97 Cu O A:Hoh608 3.53 Cu O A:Hoh653 4.02 interactive model: