Copper in the structure of Crystal Structure of FET3P, A Multicopper Oxidase That Functions in Iron Import (pdb 1zpu)

The binding sites of Copper atom in the structure of Crystal Structure of FET3P, A Multicopper Oxidase That Functions in Iron Import (pdb code 1zpu). This binding sites where shown with 5.0 Angstroms radius around Copper atom. The 1zpu structure was solved by A.B.TAYLOR, C.S.STOJ, L.ZIEGLER, D.J.KOSMAN, P.J.HART, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 50.0-2.8 Space group P32 a (A) 168.534 b (A) 168.534 c (A) 174.605 alpha (°) 90.00 beta (°) 90.00 gamma (°) 120.00 Rfactor (%) 22.6 Rfree (%) 25.7 Copper Binding Sites: Copper binding site 1 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Met345, A: Thr412, A: His413, A: Pro414, A: Cys484, A: Ile486, A: His489, A: Leu494, conact list: Atom Atom Distance (A) Cu CE A:Met345 4.98 Cu O A:Thr412 4.66 Cu NE2 A:His413 4.17 Cu N A:His413 5.00 Cu CB A:His413 3.29 Cu ND1 A:His413 2.07 Cu CD2 A:His413 4.17 Cu C A:His413 4.97 Cu CE1 A:His413 3.08 Cu CG A:His413 3.02 Cu CA A:His413 3.99 Cu CD A:Pro414 4.60 Cu CB A:Cys484 3.36 Cu SG A:Cys484 2.19 Cu CA A:Cys484 4.72 Cu CB A:Ile486 4.08 Cu CD1 A:Ile486 3.66 Cu CG2 A:Ile486 4.82 Cu CG1 A:Ile486 4.26 Cu NE2 A:His489 4.17 Cu CB A:His489 3.38 Cu ND1 A:His489 2.08 Cu CD2 A:His489 4.20 Cu CE1 A:His489 3.06 Cu CG A:His489 3.07 Cu CA A:His489 4.90 Cu CD1 A:Leu494 3.82 interactive model: Copper binding site 2 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: His81, A: Val96, A: His128, A: His416, A: His418, A: Phe481, A: His483, A: Cu11004, conact list: Atom Atom Distance (A) Cu NE2 A:His81 4.45 Cu CD2 A:His81 4.34 Cu CG2 A:Val96 4.59 Cu NE2 A:His128 2.09 Cu ND1 A:His128 4.07 Cu CD2 A:His128 3.20 Cu CE1 A:His128 2.89 Cu CG A:His128 4.24 Cu NE2 A:His416 4.78 Cu CD2 A:His416 4.24 Cu NE2 A:His418 2.14 Cu ND1 A:His418 4.16 Cu CD2 A:His418 3.22 Cu CE1 A:His418 3.00 Cu CG A:His418 4.30 Cu CB A:Phe481 4.46 Cu CD2 A:Phe481 4.17 Cu CG A:Phe481 4.73 Cu NE2 A:His483 2.21 Cu ND1 A:His483 4.25 Cu CD2 A:His483 3.09 Cu CE1 A:His483 3.20 Cu CG A:His483 4.23 Cu CU A:Cu11004 4.58 interactive model: Copper binding site 3 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 3 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: His81, A: His83, A: Trp124, A: His126, A: Ala254, A: His416, A: His485, A: Cu11004, conact list: Atom Atom Distance (A) Cu NE2 A:His81 4.19 Cu CD2 A:His81 3.85 Cu NE2 A:His83 4.01 Cu CB A:His83 3.44 Cu ND1 A:His83 1.95 Cu CD2 A:His83 4.10 Cu CE1 A:His83 2.86 Cu CG A:His83 3.02 Cu CA A:His83 4.43 Cu CZ2 A:Trp124 3.79 Cu CE2 A:Trp124 4.21 Cu NE1 A:Trp124 4.46 Cu CH2 A:Trp124 4.39 Cu NE2 A:His126 2.07 Cu ND1 A:His126 4.16 Cu CD2 A:His126 2.94 Cu CE1 A:His126 3.12 Cu CG A:His126 4.12 Cu CB A:Ala254 4.57 Cu NE2 A:His416 4.48 Cu CD2 A:His416 4.39 Cu NE2 A:His485 2.23 Cu ND1 A:His485 4.28 Cu CD2 A:His485 3.24 Cu CE1 A:His485 3.14 Cu CG A:His485 4.35 Cu CU A:Cu11004 4.07 interactive model: Copper binding site 4 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 4 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: His81, A: Phe82, A: His83, A: Gly84, A: His416, A: His418, A: Cu11002, A: Cu11003, conact list: Atom Atom Distance (A) Cu NE2 A:His81 2.08 Cu ND1 A:His81 4.06 Cu CD2 A:His81 3.22 Cu CE1 A:His81 2.87 Cu CG A:His81 4.26 Cu O A:Phe82 4.83 Cu NE2 A:His83 4.27 Cu N A:His83 4.67 Cu CB A:His83 4.10 Cu ND1 A:His83 3.61 Cu CD2 A:His83 4.13 Cu C A:His83 4.25 Cu CE1 A:His83 3.98 Cu CG A:His83 3.72 Cu CA A:His83 3.66 Cu N A:Gly84 3.82 Cu CA A:Gly84 4.90 Cu NE2 A:His416 2.05 Cu ND1 A:His416 4.08 Cu CD2 A:His416 3.07 Cu CE1 A:His416 2.96 Cu CG A:His416 4.16 Cu NE2 A:His418 3.45 Cu N A:His418 4.96 Cu CB A:His418 4.68 Cu ND1 A:His418 3.79 Cu CD2 A:His418 3.60 Cu CE1 A:His418 3.58 Cu CG A:His418 3.81 Cu CA A:His418 4.52 Cu CU A:Cu11002 4.58 Cu CU A:Cu11003 4.07 interactive model: Copper binding site 5 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 5 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: B: Thr412, B: His413, B: Pro414, B: Cys484, B: Ile486, B: His489, B: Leu494, conact list: Atom Atom Distance (A) Cu O B:Thr412 4.65 Cu NE2 B:His413 4.17 Cu N B:His413 4.92 Cu CB B:His413 3.26 Cu ND1 B:His413 2.06 Cu CD2 B:His413 4.16 Cu C B:His413 4.94 Cu CE1 B:His413 3.08 Cu CG B:His413 3.00 Cu CA B:His413 3.94 Cu CD B:Pro414 4.67 Cu CB B:Cys484 3.41 Cu SG B:Cys484 2.25 Cu CA B:Cys484 4.75 Cu CB B:Ile486 4.10 Cu CD1 B:Ile486 3.61 Cu CG2 B:Ile486 4.84 Cu CG1 B:Ile486 4.22 Cu NE2 B:His489 4.09 Cu CB B:His489 3.48 Cu ND1 B:His489 2.03 Cu CD2 B:His489 4.18 Cu CE1 B:His489 2.95 Cu CG B:His489 3.09 Cu CA B:His489 4.99 Cu CD1 B:Leu494 3.94 interactive model: Copper binding site 6 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 6 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: B: His81, B: Val96, B: His128, B: His416, B: His418, B: Phe481, B: His483, B: His485, B: Cu11004, conact list: Atom Atom Distance (A) Cu NE2 B:His81 4.58 Cu CD2 B:His81 4.53 Cu CG2 B:Val96 4.74 Cu NE2 B:His128 2.18 Cu ND1 B:His128 4.23 Cu CD2 B:His128 3.24 Cu CE1 B:His128 3.07 Cu CG B:His128 4.35 Cu NE2 B:His416 4.51 Cu CD2 B:His416 3.99 Cu NE2 B:His418 2.03 Cu ND1 B:His418 4.03 Cu CD2 B:His418 3.17 Cu CE1 B:His418 2.84 Cu CG B:His418 4.22 Cu CB B:Phe481 4.50 Cu CD2 B:Phe481 4.14 Cu CG B:Phe481 4.79 Cu NE2 B:His483 2.10 Cu ND1 B:His483 4.13 Cu CD2 B:His483 3.08 Cu CE1 B:His483 3.03 Cu CG B:His483 4.18 Cu NE2 B:His485 4.96 Cu CU B:Cu11004 4.53 interactive model: Copper binding site 7 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 7 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: B: His81, B: His83, B: Trp124, B: His126, B: Ala254, B: His416, B: His485, B: Cu11004, conact list: Atom Atom Distance (A) Cu NE2 B:His81 4.52 Cu CD2 B:His81 4.10 Cu NE2 B:His83 4.00 Cu CB B:His83 3.56 Cu ND1 B:His83 1.98 Cu CD2 B:His83 4.15 Cu CE1 B:His83 2.83 Cu CG B:His83 3.10 Cu CA B:His83 4.58 Cu CZ2 B:Trp124 3.69 Cu CE2 B:Trp124 4.13 Cu NE1 B:Trp124 4.32 Cu CH2 B:Trp124 4.37 Cu NE2 B:His126 2.02 Cu ND1 B:His126 4.12 Cu CD2 B:His126 2.95 Cu CE1 B:His126 3.05 Cu CG B:His126 4.11 Cu CB B:Ala254 4.39 Cu NE2 B:His416 4.41 Cu CD2 B:His416 4.39 Cu NE2 B:His485 2.04 Cu ND1 B:His485 4.04 Cu CD2 B:His485 3.15 Cu CE1 B:His485 2.87 Cu CG B:His485 4.19 Cu CU B:Cu11004 4.17 interactive model: Copper binding site 8 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 8 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: B: His81, B: Phe82, B: His83, B: Gly84, B: His416, B: His418, B: Cu11002, B: Cu11003, conact list: Atom Atom Distance (A) Cu NE2 B:His81 2.11 Cu ND1 B:His81 4.14 Cu CD2 B:His81 3.17 Cu CE1 B:His81 2.99 Cu CG B:His81 4.26 Cu O B:Phe82 4.78 Cu C B:Phe82 4.99 Cu NE2 B:His83 4.27 Cu N B:His83 4.60 Cu CB B:His83 4.02 Cu ND1 B:His83 3.60 Cu CD2 B:His83 4.08 Cu C B:His83 4.19 Cu CE1 B:His83 4.00 Cu CG B:His83 3.65 Cu CA B:His83 3.58 Cu N B:Gly84 3.77 Cu CA B:Gly84 4.85 Cu NE2 B:His416 1.98 Cu ND1 B:His416 3.95 Cu CD2 B:His416 3.10 Cu CE1 B:His416 2.79 Cu CG B:His416 4.13 Cu NE2 B:His418 3.51 Cu CB B:His418 4.67 Cu ND1 B:His418 3.67 Cu CD2 B:His418 3.70 Cu CE1 B:His418 3.49 Cu CG B:His418 3.80 Cu CA B:His418 4.57 Cu CU B:Cu11002 4.53 Cu CU B:Cu11003 4.17 interactive model: Copper binding site 9 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 9 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: C: Thr412, C: His413, C: Pro414, C: Cys484, C: Ile486, C: His489, C: Leu494, conact list: Atom Atom Distance (A) Cu O C:Thr412 4.63 Cu NE2 C:His413 4.30 Cu N C:His413 4.96 Cu CB C:His413 3.19 Cu ND1 C:His413 2.18 Cu CD2 C:His413 4.22 Cu C C:His413 4.88 Cu CE1 C:His413 3.25 Cu CG C:His413 3.03 Cu CA C:His413 3.93 Cu CD C:Pro414 4.58 Cu CB C:Cys484 3.32 Cu SG C:Cys484 2.25 Cu CA C:Cys484 4.70 Cu CB C:Ile486 4.22 Cu CD1 C:Ile486 3.75 Cu CG1 C:Ile486 4.23 Cu NE2 C:His489 4.17 Cu CB C:His489 3.53 Cu ND1 C:His489 2.15 Cu CD2 C:His489 4.25 Cu CE1 C:His489 3.04 Cu CG C:His489 3.17 Cu CD1 C:Leu494 3.80 interactive model: Copper binding site 10 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 10 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: C: His81, C: Val96, C: His128, C: His416, C: His418, C: Phe481, C: His483, C: His485, C: Cu11004, conact list: Atom Atom Distance (A) Cu NE2 C:His81 4.74 Cu CD2 C:His81 4.62 Cu CG2 C:Val96 4.83 Cu NE2 C:His128 2.17 Cu ND1 C:His128 4.19 Cu CD2 C:His128 3.23 Cu CE1 C:His128 3.04 Cu CG C:His128 4.32 Cu NE2 C:His416 4.66 Cu CD2 C:His416 4.00 Cu NE2 C:His418 2.23 Cu ND1 C:His418 4.28 Cu CD2 C:His418 3.27 Cu CE1 C:His418 3.13 Cu CG C:His418 4.38 Cu CB C:Phe481 4.50 Cu CD2 C:Phe481 4.17 Cu CG C:Phe481 4.76 Cu NE2 C:His483 1.98 Cu ND1 C:His483 4.04 Cu CD2 C:His483 2.96 Cu CE1 C:His483 2.95 Cu CG C:His483 4.08 Cu NE2 C:His485 4.97 Cu CU C:Cu11004 4.38 interactive model: Copper binding site 11 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 11 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: C: His81, C: His83, C: Trp124, C: His126, C: Ala254, C: His416, C: His485, C: Cu11004, conact list: Atom Atom Distance (A) Cu NE2 C:His81 4.49 Cu CD2 C:His81 4.10 Cu NE2 C:His83 4.12 Cu CB C:His83 3.53 Cu ND1 C:His83 2.07 Cu CD2 C:His83 4.23 Cu CE1 C:His83 2.97 Cu CG C:His83 3.14 Cu CA C:His83 4.59 Cu CZ2 C:Trp124 3.63 Cu CE2 C:Trp124 4.11 Cu NE1 C:Trp124 4.37 Cu CH2 C:Trp124 4.26 Cu NE2 C:His126 2.12 Cu ND1 C:His126 4.22 Cu CD2 C:His126 2.95 Cu CE1 C:His126 3.20 Cu CG C:His126 4.14 Cu CB C:Ala254 4.34 Cu NE2 C:His416 4.56 Cu CD2 C:His416 4.44 Cu NE2 C:His485 2.07 Cu ND1 C:His485 4.06 Cu CD2 C:His485 3.20 Cu CE1 C:His485 2.88 Cu CG C:His485 4.23 Cu CU C:Cu11004 4.23 interactive model: Copper binding site 12 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 12 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: C: His81, C: Phe82, C: His83, C: Gly84, C: His416, C: His418, C: Cu11002, C: Cu11003, conact list: Atom Atom Distance (A) Cu NE2 C:His81 2.09 Cu ND1 C:His81 4.07 Cu CD2 C:His81 3.15 Cu CE1 C:His81 2.93 Cu CG C:His81 4.20 Cu O C:Phe82 4.89 Cu NE2 C:His83 4.38 Cu N C:His83 4.64 Cu CB C:His83 4.12 Cu ND1 C:His83 3.63 Cu CD2 C:His83 4.23 Cu C C:His83 4.40 Cu CE1 C:His83 4.04 Cu CG C:His83 3.77 Cu CA C:His83 3.72 Cu N C:Gly84 3.99 Cu NE2 C:His416 2.02 Cu ND1 C:His416 4.11 Cu CD2 C:His416 2.97 Cu CE1 C:His416 3.03 Cu CG C:His416 4.12 Cu NE2 C:His418 3.32 Cu N C:His418 4.95 Cu CB C:His418 4.70 Cu ND1 C:His418 3.74 Cu CD2 C:His418 3.52 Cu CE1 C:His418 3.48 Cu CG C:His418 3.79 Cu CA C:His418 4.55 Cu CU C:Cu11002 4.38 Cu CU C:Cu11003 4.23 interactive model: Copper binding site 13 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 13 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: D: Thr412, D: His413, D: Pro414, D: Cys484, D: Ile486, D: His489, D: Leu494, conact list: Atom Atom Distance (A) Cu O D:Thr412 4.66 Cu NE2 D:His413 4.41 Cu N D:His413 4.95 Cu CB D:His413 3.17 Cu ND1 D:His413 2.27 Cu CD2 D:His413 4.29 Cu C D:His413 4.87 Cu CE1 D:His413 3.37 Cu CG D:His413 3.08 Cu CA D:His413 3.91 Cu CD D:Pro414 4.65 Cu CB D:Cys484 3.27 Cu SG D:Cys484 2.23 Cu CA D:Cys484 4.67 Cu CB D:Ile486 4.07 Cu CD1 D:Ile486 3.65 Cu CG2 D:Ile486 4.79 Cu CG1 D:Ile486 4.26 Cu NE2 D:His489 4.21 Cu CB D:His489 3.47 Cu ND1 D:His489 2.14 Cu CD2 D:His489 4.26 Cu CE1 D:His489 3.09 Cu CG D:His489 3.14 Cu CA D:His489 4.97 Cu CD1 D:Leu494 3.87 interactive model: Copper binding site 14 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 14 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: D: His81, D: Val96, D: His128, D: His416, D: His418, D: Phe481, D: His483, D: His485, D: Cu11004, conact list: Atom Atom Distance (A) Cu NE2 D:His81 4.65 Cu CD2 D:His81 4.50 Cu CG2 D:Val96 4.89 Cu NE2 D:His128 2.25 Cu ND1 D:His128 4.28 Cu CD2 D:His128 3.28 Cu CE1 D:His128 3.13 Cu CG D:His128 4.38 Cu NE2 D:His416 4.68 Cu CD2 D:His416 4.07 Cu NE2 D:His418 2.17 Cu ND1 D:His418 4.22 Cu CD2 D:His418 3.24 Cu CE1 D:His418 3.06 Cu CG D:His418 4.34 Cu CB D:Phe481 4.58 Cu CD2 D:Phe481 4.21 Cu CG D:Phe481 4.85 Cu NE2 D:His483 2.04 Cu ND1 D:His483 4.04 Cu CD2 D:His483 3.06 Cu CE1 D:His483 2.92 Cu CG D:His483 4.13 Cu NE2 D:His485 4.92 Cu CD2 D:His485 4.88 Cu CU D:Cu11004 4.36 interactive model: Copper binding site 15 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 15 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: D: His81, D: His83, D: Trp124, D: His126, D: Ala254, D: His416, D: His485, D: Cu11004, conact list: Atom Atom Distance (A) Cu NE2 D:His81 4.54 Cu CD2 D:His81 4.15 Cu NE2 D:His83 4.11 Cu CB D:His83 3.31 Cu ND1 D:His83 2.02 Cu CD2 D:His83 4.12 Cu CE1 D:His83 3.00 Cu CG D:His83 2.99 Cu CA D:His83 4.39 Cu CD2 D:Trp124 4.97 Cu CZ2 D:Trp124 3.58 Cu CE2 D:Trp124 3.99 Cu NE1 D:Trp124 4.18 Cu CH2 D:Trp124 4.29 Cu NE2 D:His126 2.12 Cu ND1 D:His126 4.15 Cu CD2 D:His126 3.01 Cu CE1 D:His126 3.11 Cu CG D:His126 4.14 Cu CB D:Ala254 4.38 Cu NE2 D:His416 4.57 Cu CD2 D:His416 4.56 Cu NE2 D:His485 2.18 Cu ND1 D:His485 4.15 Cu CD2 D:His485 3.31 Cu CE1 D:His485 2.96 Cu CG D:His485 4.35 Cu CU D:Cu11004 4.00 interactive model: Copper binding site 16 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 16 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: D: His81, D: Phe82, D: His83, D: Gly84, D: His416, D: His418, D: Cu11002, D: Cu11003, conact list: Atom Atom Distance (A) Cu NE2 D:His81 2.12 Cu ND1 D:His81 4.19 Cu CD2 D:His81 3.10 Cu CE1 D:His81 3.09 Cu CG D:His81 4.23 Cu O D:Phe82 4.88 Cu NE2 D:His83 4.39 Cu N D:His83 4.61 Cu CB D:His83 4.00 Cu ND1 D:His83 3.47 Cu CD2 D:His83 4.26 Cu C D:His83 4.32 Cu CE1 D:His83 3.95 Cu CG D:His83 3.69 Cu CA D:His83 3.64 Cu N D:Gly84 3.92 Cu NE2 D:His416 2.07 Cu ND1 D:His416 4.10 Cu CD2 D:His416 3.02 Cu CE1 D:His416 3.02 Cu CG D:His416 4.13 Cu NE2 D:His418 3.38 Cu CB D:His418 4.75 Cu ND1 D:His418 3.75 Cu CD2 D:His418 3.61 Cu CE1 D:His418 3.48 Cu CG D:His418 3.83 Cu CA D:His418 4.65 Cu CU D:Cu11002 4.36 Cu CU D:Cu11003 4.00 interactive model: Copper binding site 17 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 17 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: E: Met345, E: Thr412, E: His413, E: Pro414, E: Cys484, E: Ile486, E: His489, E: Leu494, conact list: Atom Atom Distance (A) Cu CE E:Met345 4.86 Cu O E:Thr412 4.78 Cu NE2 E:His413 4.31 Cu CB E:His413 3.24 Cu ND1 E:His413 2.20 Cu CD2 E:His413 4.25 Cu C E:His413 4.95 Cu CE1 E:His413 3.25 Cu CG E:His413 3.07 Cu CA E:His413 4.01 Cu CD E:Pro414 4.63 Cu CB E:Cys484 3.26 Cu SG E:Cys484 2.19 Cu CA E:Cys484 4.66 Cu CB E:Ile486 4.08 Cu CD1 E:Ile486 3.60 Cu CG2 E:Ile486 4.79 Cu CG1 E:Ile486 4.27 Cu NE2 E:His489 4.11 Cu CB E:His489 3.36 Cu ND1 E:His489 2.11 Cu CD2 E:His489 4.13 Cu CE1 E:His489 3.05 Cu CG E:His489 3.03 Cu CA E:His489 4.89 Cu CD1 E:Leu494 3.75 interactive model: Copper binding site 18 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 18 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: E: His81, E: Val96, E: His128, E: His416, E: His418, E: Phe481, E: His483, E: Cu11004, conact list: Atom Atom Distance (A) Cu NE2 E:His81 4.55 Cu CD2 E:His81 4.52 Cu CG2 E:Val96 4.69 Cu NE2 E:His128 2.18 Cu ND1 E:His128 4.20 Cu CD2 E:His128 3.24 Cu CE1 E:His128 3.05 Cu CG E:His128 4.32 Cu NE2 E:His416 4.48 Cu CD2 E:His416 4.00 Cu NE2 E:His418 2.05 Cu ND1 E:His418 4.06 Cu CD2 E:His418 3.18 Cu CE1 E:His418 2.88 Cu CG E:His418 4.23 Cu CB E:Phe481 4.38 Cu CE2 E:Phe481 4.86 Cu CD2 E:Phe481 3.96 Cu CG E:Phe481 4.63 Cu NE2 E:His483 2.16 Cu ND1 E:His483 4.18 Cu CD2 E:His483 3.05 Cu CE1 E:His483 3.14 Cu CG E:His483 4.17 Cu CU E:Cu11004 4.45 interactive model: Copper binding site 19 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 19 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: E: His81, E: His83, E: Trp124, E: His126, E: Ala254, E: His416, E: His485, E: Cu11004, conact list: Atom Atom Distance (A) Cu NE2 E:His81 4.52 Cu CD2 E:His81 4.10 Cu NE2 E:His83 4.15 Cu CB E:His83 3.39 Cu ND1 E:His83 2.09 Cu CD2 E:His83 4.19 Cu CE1 E:His83 3.05 Cu CG E:His83 3.07 Cu CA E:His83 4.54 Cu CD2 E:Trp124 4.96 Cu CZ2 E:Trp124 3.45 Cu CE2 E:Trp124 3.90 Cu NE1 E:Trp124 4.06 Cu CH2 E:Trp124 4.22 Cu NE2 E:His126 2.25 Cu ND1 E:His126 4.25 Cu CD2 E:His126 3.10 Cu CE1 E:His126 3.22 Cu CG E:His126 4.23 Cu CB E:Ala254 4.18 Cu NE2 E:His416 4.38 Cu CD2 E:His416 4.29 Cu NE2 E:His485 2.10 Cu ND1 E:His485 4.11 Cu CD2 E:His485 3.03 Cu CE1 E:His485 3.04 Cu CG E:His485 4.13 Cu CU E:Cu11004 4.17 interactive model: Copper binding site 20 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 20 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: E: His81, E: Phe82, E: His83, E: Gly84, E: His416, E: His418, E: Cu11002, E: Cu11003, conact list: Atom Atom Distance (A) Cu NE2 E:His81 2.03 Cu ND1 E:His81 4.07 Cu CD2 E:His81 3.08 Cu CE1 E:His81 2.94 Cu CG E:His81 4.17 Cu O E:Phe82 4.84 Cu NE2 E:His83 4.50 Cu N E:His83 4.60 Cu CB E:His83 3.97 Cu ND1 E:His83 3.50 Cu CD2 E:His83 4.33 Cu C E:His83 4.34 Cu CE1 E:His83 4.04 Cu CG E:His83 3.70 Cu CA E:His83 3.64 Cu N E:Gly84 3.94 Cu NE2 E:His416 1.96 Cu ND1 E:His416 3.97 Cu CD2 E:His416 3.05 Cu CE1 E:His416 2.82 Cu CG E:His416 4.11 Cu NE2 E:His418 3.58 Cu CB E:His418 4.80 Cu ND1 E:His418 3.88 Cu CD2 E:His418 3.75 Cu CE1 E:His418 3.67 Cu CG E:His418 3.94 Cu CA E:His418 4.60 Cu CU E:Cu11002 4.45 Cu CU E:Cu11003 4.17 interactive model: Copper binding site 21 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 21 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: F: Thr412, F: His413, F: Pro414, F: Cys484, F: Ile486, F: His489, F: Leu494, conact list: Atom Atom Distance (A) Cu O F:Thr412 4.60 Cu NE2 F:His413 4.42 Cu N F:His413 4.93 Cu CB F:His413 3.29 Cu ND1 F:His413 2.29 Cu CD2 F:His413 4.35 Cu C F:His413 4.84 Cu CE1 F:His413 3.36 Cu CG F:His413 3.15 Cu CA F:His413 3.89 Cu N F:Pro414 4.93 Cu CD F:Pro414 4.42 Cu CB F:Cys484 3.30 Cu SG F:Cys484 2.21 Cu CA F:Cys484 4.69 Cu N F:Ile486 4.97 Cu CB F:Ile486 3.98 Cu CD1 F:Ile486 3.52 Cu CG2 F:Ile486 4.68 Cu CG1 F:Ile486 4.15 Cu NE2 F:His489 4.03 Cu CB F:His489 3.46 Cu ND1 F:His489 2.03 Cu CD2 F:His489 4.11 Cu CE1 F:His489 2.91 Cu CG F:His489 3.05 Cu CA F:His489 4.99 Cu CD1 F:Leu494 3.83 interactive model: Copper binding site 22 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 22 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: F: His81, F: Val96, F: His128, F: His416, F: His418, F: Phe481, F: His483, F: His485, F: Cu11004, conact list: Atom Atom Distance (A) Cu NE2 F:His81 4.58 Cu CD2 F:His81 4.40 Cu CG2 F:Val96 4.70 Cu NE2 F:His128 2.19 Cu ND1 F:His128 4.28 Cu CD2 F:His128 3.14 Cu CE1 F:His128 3.18 Cu CG F:His128 4.30 Cu NE2 F:His416 4.57 Cu CD2 F:His416 3.98 Cu NE2 F:His418 2.06 Cu ND1 F:His418 4.13 Cu CD2 F:His418 3.11 Cu CE1 F:His418 2.98 Cu CG F:His418 4.22 Cu CB F:Phe481 4.44 Cu CE2 F:Phe481 4.83 Cu CD2 F:Phe481 3.98 Cu CG F:Phe481 4.64 Cu NE2 F:His483 2.07 Cu ND1 F:His483 4.08 Cu CD2 F:His483 3.10 Cu CE1 F:His483 2.95 Cu CG F:His483 4.18 Cu NE2 F:His485 4.99 Cu CD2 F:His485 4.99 Cu CU F:Cu11004 4.51 interactive model: Copper binding site 23 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 23 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: F: His81, F: His83, F: Trp124, F: His126, F: Ala254, F: His416, F: His485, F: Cu11004, conact list: Atom Atom Distance (A) Cu NE2 F:His81 4.38 Cu CD2 F:His81 4.02 Cu NE2 F:His83 4.12 Cu CB F:His83 3.30 Cu ND1 F:His83 2.02 Cu CD2 F:His83 4.13 Cu CE1 F:His83 3.01 Cu CG F:His83 2.99 Cu CA F:His83 4.35 Cu CZ2 F:Trp124 3.72 Cu CE2 F:Trp124 4.09 Cu NE1 F:Trp124 4.19 Cu CH2 F:Trp124 4.48 Cu NE2 F:His126 2.16 Cu ND1 F:His126 4.22 Cu CD2 F:His126 3.13 Cu CE1 F:His126 3.12 Cu CG F:His126 4.26 Cu CB F:Ala254 4.47 Cu NE2 F:His416 4.28 Cu CD2 F:His416 4.22 Cu CG F:His416 4.98 Cu NE2 F:His485 2.24 Cu ND1 F:His485 4.24 Cu CD2 F:His485 3.28 Cu CE1 F:His485 3.10 Cu CG F:His485 4.36 Cu CU F:Cu11004 3.96 interactive model: Copper binding site 24 out of 24 in 1zpu Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 24 of Copper in the PDB 1zpu. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: F: His81, F: Phe82, F: His83, F: Gly84, F: His416, F: His418, F: Cu11002, F: Cu11003, conact list: Atom Atom Distance (A) Cu NE2 F:His81 2.04 Cu ND1 F:His81 4.10 Cu CD2 F:His81 3.08 Cu CE1 F:His81 2.96 Cu CG F:His81 4.19 Cu O F:Phe82 4.66 Cu C F:Phe82 4.86 Cu NE2 F:His83 4.45 Cu N F:His83 4.46 Cu CB F:His83 3.90 Cu ND1 F:His83 3.53 Cu CD2 F:His83 4.24 Cu C F:His83 4.11 Cu CE1 F:His83 4.06 Cu CG F:His83 3.65 Cu CA F:His83 3.48 Cu N F:Gly84 3.67 Cu CA F:Gly84 4.78 Cu NE2 F:His416 2.09 Cu ND1 F:His416 4.13 Cu CD2 F:His416 3.12 Cu CE1 F:His416 2.99 Cu CG F:His416 4.22 Cu NE2 F:His418 3.70 Cu CB F:His418 4.87 Cu ND1 F:His418 3.88 Cu CD2 F:His418 3.92 Cu CE1 F:His418 3.69 Cu CG F:His418 4.03 Cu CA F:His418 4.65 Cu CU F:Cu11002 4.51 Cu CU F:Cu11003 3.96 interactive model: