Chemical elements
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    PDB 1a2v-1bxu
    PDB 1bxv-1fwx
    PDB 1g3d-1j9t
    PDB 1jcv-1mfm
    PDB 1mg2-1paz
    PDB 1pcs-1sii
    PDB 1sjm-1w6w
      1sjm
      1slv
      1snr
      1sos
      1spd
      1spu
      1srd
      1sxa
      1sxb
      1sxc
      1sxn
      1sxs
      1sxz
      1t16
      1t2x
      1tef
      1teg
      1tho
      1tkw
      1tl4
      1tmx
      1to4
      1to5
      1tu2
      1tu5
      1txx
      1u96
      1uat
      1ui7
      1ui8
      1uku
      1uri
      1us1
      1uux
      1uuy
      1uvw
      1uxl
      1uxm
      1v10
      1v54
      1v55
      1v6p
      1v99
      1w2z
      1w4n
      1w5z
      1w6c
      1w6g
      1w6l
      1w6w
    PDB 1w77-2afn
    PDB 2ahk-2dv6
    PDB 2dws-2ggp
    PDB 2ghz-2mta
    PDB 2nrd-2vm3
    PDB 2vm4-2yah
    PDB 2yam-3bkt
    PDB 3bqv-3fyi
    PDB 3g5w-3mie
    PDB 3mif-3t6v
    PDB 3t6w-9pcy

Copper in the structure of A4V Mutant of Human SOD1 (pdb 1uxm)






The binding sites of Copper atom in the structure of A4V Mutant of Human SOD1 (pdb code 1uxm). This binding sites where shown with 5.0 Angstroms radius around Copper atom.
The 1uxm structure was solved by M.A.HOUGH, J.G.GROSSMANN, S.V.ANTONYUK, R.W.STRANGE, P.A.DOUCETTE, J.A.RODRIGUEZ, L.J.WHITSON, P.J.HART, L.J.HAYWARD, J.S.VALENTINE, S.S.HASNAIN, with X-Ray Crystallography technique, brief refinement statistics is given in the table below:
Resolution (A)27.0-1.9
Space groupP1211
a (A)112.374
b (A)145.582
c (A)112.497
alpha (°)90.00
beta (°)120.05
gamma (°)90.00
Rfactor (%)22.8
Rfree (%)25


Copper Binding Sites:

Copper binding site 1 out of 12 in 1uxm


Copper binding site 1 out of 12 in 1uxm
Click to enlarge
stereopicture of Copper binding site 1 out of 12 in 1uxm
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Copper in the PDB 1uxm. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: A: His46, A: His48, A: His63, A: Val118, A: His120, A: Hoh2060, A: Hoh2124, A: Hoh2126,

conact list:


AtomAtomDistance (A)
CuNE2 A:His464.20
CuN A:His464.90
CuCB A:His463.46
CuND1 A:His462.18
CuCD2 A:His464.24
CuCE1 A:His463.11
CuCG A:His463.14
CuCA A:His464.73
CuNE2 A:His482.13
CuND1 A:His483.98
CuCD2 A:His483.33
CuCE1 A:His482.77
CuCG A:His484.28
CuNE2 A:His632.36
CuND1 A:His634.40
CuCD2 A:His633.05
CuCE1 A:His633.44
CuCG A:His634.25
CuCB A:Val1184.79
CuCG1 A:Val1184.85
CuNE2 A:His1202.08
CuND1 A:His1204.15
CuCD2 A:His1203.01
CuCE1 A:His1203.08
CuCG A:His1204.15
CuO A:Hoh20601.86
CuO A:Hoh21244.82
CuO A:Hoh21264.31

interactive model:


Copper binding site 2 out of 12 in 1uxm


Copper binding site 2 out of 12 in 1uxm
Click to enlarge
stereopicture of Copper binding site 2 out of 12 in 1uxm
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Copper in the PDB 1uxm. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: B: His46, B: His48, B: His63, B: Val118, B: His120, B: Hoh2062, B: Hoh2119, B: Hoh2123,

conact list:


AtomAtomDistance (A)
CuNE2 B:His464.18
CuN B:His464.95
CuCB B:His463.35
CuND1 B:His462.12
CuCD2 B:His464.20
CuCE1 B:His463.09
CuCG B:His463.07
CuCA B:His464.71
CuNE2 B:His482.15
CuND1 B:His484.07
CuCD2 B:His483.30
CuCE1 B:His482.87
CuCG B:His484.31
CuNE2 B:His632.22
CuND1 B:His634.31
CuCD2 B:His632.94
CuCE1 B:His633.33
CuCG B:His634.17
CuCB B:Val1184.75
CuCG1 B:Val1184.89
CuNE2 B:His1202.19
CuND1 B:His1204.29
CuCD2 B:His1203.04
CuCE1 B:His1203.25
CuCG B:His1204.23
CuO B:Hoh20622.21
CuO B:Hoh21194.73
CuO B:Hoh21234.35

interactive model:


Copper binding site 3 out of 12 in 1uxm


Copper binding site 3 out of 12 in 1uxm
Click to enlarge
stereopicture of Copper binding site 3 out of 12 in 1uxm
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 3 of Copper in the PDB 1uxm. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: C: His46, C: His48, C: His63, C: Val118, C: His120, C: Hoh2063, C: Hoh2130,

conact list:


AtomAtomDistance (A)
CuNE2 C:His464.25
CuN C:His464.94
CuCB C:His463.49
CuND1 C:His462.22
CuCD2 C:His464.30
CuCE1 C:His463.14
CuCG C:His463.20
CuCA C:His464.78
CuNE2 C:His482.09
CuND1 C:His484.01
CuCD2 C:His483.19
CuCE1 C:His482.84
CuCG C:His484.20
CuNE2 C:His632.29
CuND1 C:His634.35
CuCD2 C:His633.11
CuCE1 C:His633.32
CuCG C:His634.28
CuCB C:Val1184.72
CuCG1 C:Val1184.74
CuNE2 C:His1202.09
CuND1 C:His1204.15
CuCD2 C:His1203.03
CuCE1 C:His1203.07
CuCG C:His1204.17
CuO C:Hoh20632.44
CuO C:Hoh21304.48

interactive model:


Copper binding site 4 out of 12 in 1uxm


Copper binding site 4 out of 12 in 1uxm
Click to enlarge
stereopicture of Copper binding site 4 out of 12 in 1uxm
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 4 of Copper in the PDB 1uxm. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: D: His46, D: His48, D: His63, D: Val118, D: His120, D: Hoh2063, D: Hoh2112, D: Hoh2113,

conact list:


AtomAtomDistance (A)
CuNE2 D:His464.10
CuN D:His464.98
CuCB D:His463.49
CuND1 D:His462.09
CuCD2 D:His464.19
CuCE1 D:His462.98
CuCG D:His463.12
CuCA D:His464.81
CuNE2 D:His482.12
CuND1 D:His484.05
CuCD2 D:His483.25
CuCE1 D:His482.86
CuCG D:His484.27
CuNE2 D:His632.36
CuND1 D:His634.45
CuCD2 D:His633.07
CuCE1 D:His633.46
CuCG D:His634.29
CuCB D:Val1184.71
CuCG1 D:Val1184.79
CuNE2 D:His1202.05
CuND1 D:His1204.08
CuCD2 D:His1203.03
CuCE1 D:His1202.99
CuCG D:His1204.15
CuO D:Hoh20632.14
CuO D:Hoh21124.87
CuO D:Hoh21134.43

interactive model:


Copper binding site 5 out of 12 in 1uxm


Copper binding site 5 out of 12 in 1uxm
Click to enlarge
stereopicture of Copper binding site 5 out of 12 in 1uxm
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 5 of Copper in the PDB 1uxm. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: E: His46, E: His48, E: His63, E: Val118, E: His120, E: Hoh2032, E: Hoh2069,

conact list:


AtomAtomDistance (A)
CuNE2 E:His464.09
CuN E:His464.96
CuCB E:His463.41
CuND1 E:His462.08
CuCD2 E:His464.15
CuCE1 E:His463.00
CuCG E:His463.07
CuCA E:His464.75
CuNE2 E:His482.21
CuND1 E:His484.14
CuCD2 E:His483.30
CuCE1 E:His482.98
CuCG E:His484.32
CuNE2 E:His632.20
CuND1 E:His634.29
CuCD2 E:His632.96
CuCE1 E:His633.30
CuCG E:His634.16
CuCB E:Val1184.70
CuCG1 E:Val1184.76
CuNE2 E:His1202.02
CuND1 E:His1203.98
CuCD2 E:His1203.07
CuCE1 E:His1202.85
CuCG E:His1204.11
CuO E:Hoh20322.35
CuO E:Hoh20694.47

interactive model:


Copper binding site 6 out of 12 in 1uxm


Copper binding site 6 out of 12 in 1uxm
Click to enlarge
stereopicture of Copper binding site 6 out of 12 in 1uxm
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 6 of Copper in the PDB 1uxm. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: F: His46, F: His48, F: His63, F: Val118, F: His120, F: Hoh2018, F: Hoh2019,

conact list:


AtomAtomDistance (A)
CuNE2 F:His464.15
CuN F:His464.93
CuCB F:His463.54
CuND1 F:His462.17
CuCD2 F:His464.23
CuCE1 F:His463.04
CuCG F:His463.17
CuCA F:His464.80
CuNE2 F:His482.14
CuND1 F:His484.09
CuCD2 F:His483.30
CuCE1 F:His482.89
CuCG F:His484.31
CuNE2 F:His632.43
CuND1 F:His634.53
CuCD2 F:His633.12
CuCE1 F:His633.54
CuCG F:His634.36
CuCB F:Val1184.74
CuCG1 F:Val1184.74
CuNE2 F:His1201.99
CuND1 F:His1203.98
CuCD2 F:His1203.08
CuCE1 F:His1202.84
CuCG F:His1204.13
CuO F:Hoh20182.03
CuO F:Hoh20194.07

interactive model:


Copper binding site 7 out of 12 in 1uxm


Copper binding site 7 out of 12 in 1uxm
Click to enlarge
stereopicture of Copper binding site 7 out of 12 in 1uxm
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 7 of Copper in the PDB 1uxm. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: G: His46, G: His48, G: His63, G: Val118, G: His120, G: Hoh2030, G: Hoh2070, G: Hoh2072,

conact list:


AtomAtomDistance (A)
CuNE2 G:His464.09
CuN G:His464.95
CuCB G:His463.47
CuND1 G:His462.07
CuCD2 G:His464.16
CuCE1 G:His462.97
CuCG G:His463.09
CuCA G:His464.80
CuNE2 G:His482.17
CuND1 G:His484.08
CuCD2 G:His483.31
CuCE1 G:His482.90
CuCG G:His484.31
CuNE2 G:His632.36
CuND1 G:His634.42
CuCD2 G:His633.04
CuCE1 G:His633.46
CuCG G:His634.25
CuCB G:Val1184.72
CuCG1 G:Val1184.72
CuNE2 G:His1202.15
CuND1 G:His1204.16
CuCD2 G:His1203.12
CuCE1 G:His1203.05
CuCG G:His1204.22
CuO G:Hoh20302.43
CuO G:Hoh20704.85
CuO G:Hoh20724.29

interactive model:


Copper binding site 8 out of 12 in 1uxm


Copper binding site 8 out of 12 in 1uxm
Click to enlarge
stereopicture of Copper binding site 8 out of 12 in 1uxm
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 8 of Copper in the PDB 1uxm. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: H: His46, H: His48, H: His63, H: Val118, H: His120, H: Hoh2029, H: Hoh2064, H: Hoh2065, H: Hoh2077, H: Hoh2080,

conact list:


AtomAtomDistance (A)
CuNE2 H:His463.86
CuCB H:His463.73
CuND1 H:His462.05
CuCD2 H:His464.09
CuCE1 H:His462.71
CuCG H:His463.17
CuCA H:His464.92
CuNE2 H:His482.26
CuND1 H:His484.31
CuCD2 H:His483.22
CuCE1 H:His483.22
CuCG H:His484.35
CuNE2 H:His632.22
CuND1 H:His634.33
CuCD2 H:His633.05
CuCE1 H:His633.30
CuCG H:His634.25
CuCB H:Val1184.94
CuCG1 H:Val1184.72
CuNE2 H:His1202.05
CuND1 H:His1204.12
CuCD2 H:His1202.86
CuCE1 H:His1203.12
CuCG H:His1204.03
CuO H:Hoh20293.89
CuO H:Hoh20644.13
CuO H:Hoh20652.62
CuO H:Hoh20774.83
CuO H:Hoh20804.34

interactive model:


Copper binding site 9 out of 12 in 1uxm


Copper binding site 9 out of 12 in 1uxm
Click to enlarge
stereopicture of Copper binding site 9 out of 12 in 1uxm
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 9 of Copper in the PDB 1uxm. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: I: His46, I: His48, I: His63, I: Val118, I: His120, I: Hoh2015, I: Hoh2031,

conact list:


AtomAtomDistance (A)
CuNE2 I:His464.16
CuN I:His464.92
CuCB I:His463.37
CuND1 I:His462.34
CuCD2 I:His464.12
CuCE1 I:His463.22
CuCG I:His463.09
CuCA I:His464.71
CuNE2 I:His482.28
CuND1 I:His484.14
CuCD2 I:His483.33
CuCE1 I:His483.02
CuCG I:His484.32
CuNE2 I:His631.97
CuND1 I:His633.95
CuCD2 I:His632.64
CuCE1 I:His633.05
CuCG I:His633.79
CuCB I:Val1184.73
CuCG1 I:Val1184.81
CuNE2 I:His1202.17
CuND1 I:His1204.29
CuCD2 I:His1202.96
CuCE1 I:His1203.27
CuCG I:His1204.17
CuO I:Hoh20154.07
CuO I:Hoh20312.28

interactive model:


Copper binding site 10 out of 12 in 1uxm


Copper binding site 10 out of 12 in 1uxm
Click to enlarge
stereopicture of Copper binding site 10 out of 12 in 1uxm
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 10 of Copper in the PDB 1uxm. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: J: His46, J: His48, J: His63, J: Val118, J: His120, J: Hoh2030, J: Hoh2066,

conact list:


AtomAtomDistance (A)
CuNE2 J:His464.02
CuN J:His464.94
CuCB J:His463.49
CuND1 J:His462.01
CuCD2 J:His464.13
CuCE1 J:His462.88
CuCG J:His463.07
CuCA J:His464.79
CuNE2 J:His482.24
CuND1 J:His484.18
CuCD2 J:His483.35
CuCE1 J:His483.00
CuCG J:His484.38
CuNE2 J:His632.15
CuND1 J:His634.25
CuCD2 J:His632.93
CuCE1 J:His633.25
CuCG J:His634.13
CuCB J:Val1184.66
CuCG1 J:Val1184.51
CuNE2 J:His1202.04
CuND1 J:His1204.09
CuCD2 J:His1203.01
CuCE1 J:His1203.00
CuCG J:His1204.13
CuO J:Hoh20302.28
CuO J:Hoh20664.29

interactive model:


Copper binding site 11 out of 12 in 1uxm


Copper binding site 11 out of 12 in 1uxm
Click to enlarge
stereopicture of Copper binding site 11 out of 12 in 1uxm
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 11 of Copper in the PDB 1uxm. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: K: His46, K: His48, K: His63, K: Val118, K: His120, K: Thr137, K: Hoh2021, K: Hoh2063, K: Hoh2064, K: Hoh2067,

conact list:


AtomAtomDistance (A)
CuNE2 K:His464.11
CuCB K:His463.42
CuND1 K:His462.07
CuCD2 K:His464.17
CuCE1 K:His462.99
CuCG K:His463.08
CuCA K:His464.78
CuNE2 K:His482.18
CuND1 K:His484.10
CuCD2 K:His483.32
CuCE1 K:His482.91
CuCG K:His484.33
CuNE2 K:His632.26
CuND1 K:His634.39
CuCD2 K:His633.01
CuCE1 K:His633.39
CuCG K:His634.24
CuCB K:Val1184.84
CuCG1 K:Val1184.86
CuNE2 K:His1202.13
CuND1 K:His1204.16
CuCD2 K:His1203.09
CuCE1 K:His1203.06
CuCG K:His1204.20
CuO K:Thr1374.98
CuO K:Hoh20212.35
CuO K:Hoh20634.70
CuO K:Hoh20644.77
CuO K:Hoh20674.40

interactive model:


Copper binding site 12 out of 12 in 1uxm


Copper binding site 12 out of 12 in 1uxm
Click to enlarge
stereopicture of Copper binding site 12 out of 12 in 1uxm
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 12 of Copper in the PDB 1uxm. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: L: His46, L: His48, L: His63, L: Val118, L: His120, L: Hoh2023, L: Hoh2024,

conact list:


AtomAtomDistance (A)
CuNE2 L:His464.12
CuN L:His464.79
CuCB L:His463.30
CuND1 L:His462.11
CuCD2 L:His464.12
CuCE1 L:His463.06
CuCG L:His463.01
CuCA L:His464.62
CuNE2 L:His482.16
CuND1 L:His484.02
CuCD2 L:His483.25
CuCE1 L:His482.87
CuCG L:His484.23
CuNE2 L:His631.96
CuND1 L:His634.10
CuCD2 L:His632.81
CuCE1 L:His633.06
CuCG L:His634.01
CuCB L:Val1184.70
CuCG1 L:Val1184.72
CuNE2 L:His1202.23
CuND1 L:His1204.35
CuCD2 L:His1203.10
CuCE1 L:His1203.29
CuCG L:His1204.30
CuO L:Hoh20232.47
CuO L:Hoh20244.65

interactive model:




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