Copper in PDB 1rzc: X-Ray Analysis of Metal Substituted Human Carbonic Anhydrase II Derivatives

All present enzymatic activity of X-Ray Analysis of Metal Substituted Human Carbonic Anhydrase II Derivatives:
4.2.1.1;

The structure of X-Ray Analysis of Metal Substituted Human Carbonic Anhydrase II Derivatives, PDB code: 1rzc was solved by K.Hakansson, A.Wehnert, A.Liljas, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	N/A / 1.90
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.700, 41.700, 73.000, 90.00, 104.60, 90.00
R / Rfree (%)	n/a / n/a

The binding sites of Copper atom in the X-Ray Analysis of Metal Substituted Human Carbonic Anhydrase II Derivatives (pdb code 1rzc). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 2 binding sites of Copper where determined in the X-Ray Analysis of Metal Substituted Human Carbonic Anhydrase II Derivatives, PDB code: 1rzc:
Jump to Copper binding site number: 1; 2;

Copper binding site 1 out of 2 in the X-Ray Analysis of Metal Substituted Human Carbonic Anhydrase II Derivatives


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of X-Ray Analysis of Metal Substituted Human Carbonic Anhydrase II Derivatives within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu262 b:8.9 occ:1.00 ND1 A:HIS119 2.1 3.5 1.0 NE2 A:HIS96 2.2 3.8 1.0 O A:HOH263 2.3 7.5 1.0 NE2 A:HIS94 2.3 6.0 1.0 O2 A:OXY500 2.4 11.9 1.0 CE1 A:HIS119 3.0 4.9 1.0 CG A:HIS119 3.1 4.9 1.0 CD2 A:HIS96 3.1 2.4 1.0 CE1 A:HIS94 3.2 7.3 1.0 CE1 A:HIS96 3.2 4.0 1.0 O1 A:OXY500 3.3 12.4 1.0 CD2 A:HIS94 3.3 6.7 1.0 CB A:HIS119 3.5 3.2 1.0 OG1 A:THR199 3.7 3.3 1.0 OE1 A:GLU106 4.1 4.0 1.0 NE2 A:HIS119 4.2 3.9 1.0 CD2 A:HIS119 4.2 6.1 1.0 CG A:HIS96 4.2 2.0 1.0 ND1 A:HIS96 4.3 2.1 1.0 ND1 A:HIS94 4.3 6.7 1.0 CG A:HIS94 4.4 6.4 1.0 O A:HOH292 4.4 25.9 1.0 CD A:GLU106 5.0 5.6 1.0

Copper binding site 2 out of 2 in the X-Ray Analysis of Metal Substituted Human Carbonic Anhydrase II Derivatives


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of X-Ray Analysis of Metal Substituted Human Carbonic Anhydrase II Derivatives within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu501 b:12.1 occ:0.20 NE2 A:HIS4 2.5 15.0 0.5 NE2 A:HIS64 2.6 4.4 0.4 CE1 A:HIS64 2.6 5.6 0.4 CE1 A:HIS4 2.9 14.8 0.5 CD2 A:HIS4 3.7 16.7 0.5 ND1 A:HIS64 3.8 6.4 0.4 O A:HOH332 3.9 25.4 0.7 CD2 A:HIS64 3.9 6.2 0.4 ND1 A:HIS4 4.1 16.1 0.5 O A:ASN62 4.2 14.3 1.0 CD2 A:HIS64 4.5 15.7 0.6 NE1 A:TRP5 4.5 10.4 1.0 CG A:HIS64 4.5 7.1 0.4 CG A:HIS4 4.6 17.7 0.5 CZ2 A:TRP5 4.7 10.0 1.0 CE2 A:TRP5 4.8 11.4 1.0

K.Hakansson, A.Wehnert, A.Liljas. X-Ray Analysis of Metal-Substituted Human Carbonic Anhydrase II Derivatives. Acta Crystallogr.,Sect.D V. 50 93 1994.
ISSN: ISSN 0907-4449
PubMed: 15299481
DOI: 10.1107/S0907444993008790