Copper in PDB 1q05: Crystal Structure of the Cu(I) Form of E. Coli Cuer, A Copper Efflux Regulator

The structure of Crystal Structure of the Cu(I) Form of E. Coli Cuer, A Copper Efflux Regulator, PDB code: 1q05 was solved by A.Changela, K.Chen, Y.Xue, J.Holschen, C.E.Outten, T.V.O'halloran, A.Mondragon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	23.92 / 2.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	59.160, 66.260, 81.290, 90.00, 90.00, 90.00
R / Rfree (%)	20.8 / 25.3

The binding sites of Copper atom in the Crystal Structure of the Cu(I) Form of E. Coli Cuer, A Copper Efflux Regulator (pdb code 1q05). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 2 binding sites of Copper where determined in the Crystal Structure of the Cu(I) Form of E. Coli Cuer, A Copper Efflux Regulator, PDB code: 1q05:
Jump to Copper binding site number: 1; 2;

Copper binding site 1 out of 2 in the Crystal Structure of the Cu(I) Form of E. Coli Cuer, A Copper Efflux Regulator


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Crystal Structure of the Cu(I) Form of E. Coli Cuer, A Copper Efflux Regulator within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu302 b:40.7 occ:1.00 SG A:CYS120 2.2 38.5 1.0 SG A:CYS112 2.2 47.0 1.0 CB A:CYS120 3.1 39.5 1.0 CB A:CYS112 3.1 53.2 1.0 CA A:CYS120 3.3 39.1 1.0 O B:SER77 3.5 54.3 1.0 CD1 A:ILE122 3.6 37.8 1.0 CG1 A:ILE122 3.6 38.4 1.0 CD A:PRO121 3.7 38.5 1.0 C A:CYS120 3.8 38.2 1.0 N A:PRO121 3.8 38.5 1.0 CA B:SER77 4.0 56.0 1.0 N A:ILE122 4.0 37.6 1.0 CB A:ILE122 4.1 37.8 1.0 C B:SER77 4.2 54.9 1.0 CA A:CYS112 4.2 55.4 1.0 CB B:SER77 4.3 56.1 1.0 OG B:SER77 4.5 58.3 1.0 CB B:VAL80 4.6 45.6 1.0 N A:CYS120 4.7 39.6 1.0 CA A:ILE122 4.7 38.0 1.0 O A:CYS120 4.7 37.8 1.0 N B:LYS81 4.7 45.6 1.0 CG1 B:VAL80 4.7 44.1 1.0 CB B:LYS81 4.8 46.7 1.0 CD A:PRO113 4.9 59.5 1.0 CA A:PRO121 4.9 38.0 1.0 C A:CYS112 4.9 57.0 1.0 N A:GLY114 4.9 61.1 1.0 C A:PRO121 5.0 38.1 1.0

Copper binding site 2 out of 2 in the Crystal Structure of the Cu(I) Form of E. Coli Cuer, A Copper Efflux Regulator


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Crystal Structure of the Cu(I) Form of E. Coli Cuer, A Copper Efflux Regulator within 5.0Å range: probe atom residue distance (Å) B Occ B:Cu301 b:26.4 occ:1.00 SG B:CYS112 2.1 24.5 1.0 SG B:CYS120 2.1 29.8 1.0 CB B:CYS120 3.1 30.4 1.0 CB B:CYS112 3.2 24.8 1.0 CB A:SER77 3.4 27.4 1.0 CA B:CYS120 3.5 31.5 1.0 O A:SER77 3.6 28.1 1.0 CG1 B:ILE122 3.7 28.3 1.0 CD1 B:ILE122 3.7 26.7 1.0 CD B:PRO121 3.8 28.7 1.0 CA A:SER77 3.9 28.4 1.0 C B:CYS120 4.0 31.7 1.0 N B:PRO121 4.1 29.9 1.0 CA B:CYS112 4.1 27.0 1.0 CB B:ILE122 4.1 28.4 1.0 C A:SER77 4.1 29.1 1.0 N B:ILE122 4.2 28.7 1.0 CB A:VAL80 4.3 28.0 1.0 OG A:SER77 4.4 27.9 1.0 CD B:PRO113 4.5 28.6 1.0 CG B:PRO121 4.5 32.5 1.0 N A:LYS81 4.6 24.6 1.0 CG1 A:VAL80 4.7 28.0 1.0 O B:ASP119 4.7 36.5 1.0 N B:CYS120 4.8 34.4 1.0 CA B:ILE122 4.8 27.9 1.0 O B:CYS120 4.8 32.9 1.0 CB A:LYS81 4.9 24.6 1.0 C B:CYS112 4.9 28.8 1.0 N B:PRO113 4.9 29.5 1.0 CG2 A:VAL80 5.0 28.2 1.0

A.Changela, K.Chen, Y.Xue, J.Holschen, C.E.Outten, T.V.O'halloran, A.Mondragon. Molecular Basis of Metal-Ion Selectivity and Zeptomolar Sensitivity By Cuer Science V. 301 1383 2003.
ISSN: ISSN 0036-8075
PubMed: 12958362
DOI: 10.1126/SCIENCE.1085950