Copper in the structure of Crystal Structure of E. Coli Amine Oxidase Complexed With Tranylcypromine (pdb 1lvn)

The binding sites of Copper atom in the structure of Crystal Structure of E. Coli Amine Oxidase Complexed With Tranylcypromine (pdb code 1lvn). This binding sites where shown with 5.0 Angstroms radius around Copper atom. The 1lvn structure was solved by C.M.WILMOT, S.E.PHILLIPS, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 20.0-2.4 Space group P212121 a (A) 135.236 b (A) 166.482 c (A) 79.628 alpha (°) 90.00 beta (°) 90.00 gamma (°) 90.00 Rfactor (%) 18.5 Rfree (%) 22.9 Copper Binding Sites: Copper binding site 1 out of 2 in 1lvn Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Copper in the PDB 1lvn. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Tyt466, A: His524, A: His526, A: His613, A: His689, A: Met699, A: Hoh1466, A: Hoh1474, A: Hoh1628, conact list: Atom Atom Distance (A) Cu O3 A:Tyt466 4.63 Cu NE2 A:His524 2.27 Cu ND1 A:His524 4.25 Cu CD2 A:His524 3.23 Cu CE1 A:His524 3.16 Cu CG A:His524 4.32 Cu NE2 A:His526 2.04 Cu ND1 A:His526 4.15 Cu CD2 A:His526 2.85 Cu CE1 A:His526 3.14 Cu CG A:His526 4.05 Cu CE1 A:His613 4.98 Cu NE2 A:His689 4.38 Cu CB A:His689 3.38 Cu ND1 A:His689 2.27 Cu CD2 A:His689 4.35 Cu CE1 A:His689 3.30 Cu CG A:His689 3.18 Cu CA A:His689 4.93 Cu CE A:Met699 4.12 Cu SD A:Met699 4.88 Cu O A:Hoh1466 2.61 Cu O A:Hoh1474 4.64 Cu O A:Hoh1628 3.73 interactive model: Copper binding site 2 out of 2 in 1lvn Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Copper in the PDB 1lvn. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: B: Tyt466, B: His524, B: His526, B: His613, B: His689, B: Met699, B: Hoh2019, B: Hoh2165, B: Hoh2423, conact list: Atom Atom Distance (A) Cu O3 B:Tyt466 4.73 Cu NE2 B:His524 2.46 Cu ND1 B:His524 4.51 Cu CD2 B:His524 3.29 Cu CE1 B:His524 3.47 Cu CG B:His524 4.46 Cu NE2 B:His526 2.10 Cu ND1 B:His526 4.22 Cu CD2 B:His526 2.93 Cu CE1 B:His526 3.19 Cu CG B:His526 4.13 Cu CE1 B:His613 4.87 Cu NE2 B:His689 4.25 Cu CB B:His689 3.36 Cu ND1 B:His689 2.14 Cu CD2 B:His689 4.25 Cu CE1 B:His689 3.15 Cu CG B:His689 3.09 Cu CA B:His689 4.90 Cu SD B:Met699 4.69 Cu O B:Hoh2019 4.76 Cu O B:Hoh2165 4.00 Cu O B:Hoh2423 2.66 interactive model: