Copper in PDB 1lcf: Crystal Structure of Copper-and Oxalate-Substituted Human Lactoferrin at 2.0 Angstroms Resolution

The structure of Crystal Structure of Copper-and Oxalate-Substituted Human Lactoferrin at 2.0 Angstroms Resolution, PDB code: 1lcf was solved by C.A.Smith, B.F.Anderson, H.M.Baker, E.N.Baker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	8.00 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	155.800, 97.100, 56.200, 90.00, 90.00, 90.00
R / Rfree (%)	n/a / n/a

The binding sites of Copper atom in the Crystal Structure of Copper-and Oxalate-Substituted Human Lactoferrin at 2.0 Angstroms Resolution (pdb code 1lcf). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 2 binding sites of Copper where determined in the Crystal Structure of Copper-and Oxalate-Substituted Human Lactoferrin at 2.0 Angstroms Resolution, PDB code: 1lcf:
Jump to Copper binding site number: 1; 2;

Copper binding site 1 out of 2 in the Crystal Structure of Copper-and Oxalate-Substituted Human Lactoferrin at 2.0 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of Crystal Structure of Copper-and Oxalate-Substituted Human Lactoferrin at 2.0 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu693 b:34.8 occ:1.00 OD1 A:ASP60 1.9 31.2 1.0 OH A:TYR192 2.0 30.3 1.0 NE2 A:HIS253 2.0 28.7 1.0 O2 A:CO3695 2.0 34.7 1.0 OH A:TYR92 2.6 24.3 1.0 O1 A:CO3695 2.6 30.6 1.0 CE1 A:HIS253 2.7 29.8 1.0 C A:CO3695 2.7 29.3 1.0 CG A:ASP60 3.0 27.5 1.0 CZ A:TYR192 3.1 23.7 1.0 CD2 A:HIS253 3.2 24.3 1.0 CZ A:TYR92 3.5 19.0 1.0 CB A:ASP60 3.7 25.9 1.0 CE1 A:TYR192 3.9 26.5 1.0 O3 A:CO3695 3.9 26.4 1.0 ND1 A:HIS253 3.9 25.8 1.0 CE2 A:TYR192 4.0 24.1 1.0 OD2 A:ASP60 4.0 26.5 1.0 NH2 A:ARG210 4.1 16.2 1.0 CE2 A:TYR92 4.1 16.1 1.0 O A:HOH992 4.1 27.0 1.0 NH2 A:ARG121 4.2 30.2 1.0 CG A:HIS253 4.2 23.6 1.0 CE1 A:TYR92 4.3 20.9 1.0 NE A:ARG121 4.3 33.4 1.0 CA A:ASP60 4.4 28.6 1.0 CZ A:ARG121 4.6 32.9 1.0 CB A:THR122 4.8 20.3 1.0 OG1 A:THR122 5.0 22.7 1.0

Copper binding site 2 out of 2 in the Crystal Structure of Copper-and Oxalate-Substituted Human Lactoferrin at 2.0 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of Crystal Structure of Copper-and Oxalate-Substituted Human Lactoferrin at 2.0 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cu694 b:28.9 occ:1.00 O2 A:OXL696 1.9 17.7 1.0 OH A:TYR435 2.0 28.1 1.0 O1 A:OXL696 2.0 19.3 1.0 NE2 A:HIS597 2.1 18.5 1.0 OD1 A:ASP395 2.1 37.0 1.0 OH A:TYR528 2.6 22.9 1.0 C1 A:OXL696 2.7 17.6 1.0 C2 A:OXL696 2.7 17.3 1.0 CE1 A:HIS597 2.8 17.1 1.0 CZ A:TYR435 3.0 25.7 1.0 CG A:ASP395 3.3 31.2 1.0 CD2 A:HIS597 3.3 17.1 1.0 CE2 A:TYR435 3.4 25.8 1.0 CZ A:TYR528 3.6 17.9 1.0 O A:HOH1076 3.9 23.5 1.0 CB A:ASP395 3.9 26.2 1.0 O3 A:OXL696 4.0 21.3 1.0 CE1 A:TYR435 4.0 22.3 1.0 ND1 A:HIS597 4.0 15.7 1.0 O4 A:OXL696 4.0 24.4 1.0 O A:HOH991 4.2 32.2 1.0 CG A:HIS597 4.3 13.6 1.0 CE1 A:TYR528 4.3 17.1 1.0 OD2 A:ASP395 4.3 28.5 1.0 CE2 A:TYR528 4.3 20.7 1.0 CA A:ASP395 4.4 25.1 1.0 O A:HOH1205 4.7 57.1 1.0 N A:THR466 4.7 23.3 1.0 N A:ALA467 4.7 23.9 1.0 CD2 A:TYR435 4.7 25.8 1.0 CB A:THR466 4.8 27.5 1.0 CB A:ARG465 4.8 28.6 1.0 OG1 A:THR466 4.9 27.6 1.0 O A:HOH1204 5.0 43.6 1.0

C.A.Smith, B.F.Anderson, H.M.Baker, E.N.Baker. Structure of Copper- and Oxalate-Substituted Human Lactoferrin at 2.0 A Resolution. Acta Crystallogr.,Sect.D V. 50 302 1994.
ISSN: ISSN 0907-4449
PubMed: 15299444
DOI: 10.1107/S0907444994000491