Atomistry » Copper » PDB 1jxd-1mfm » 1kcw
Atomistry »
  Copper »
    PDB 1jxd-1mfm »
      1kcw »

Copper in PDB 1kcw: X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms

Enzymatic activity of X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms

All present enzymatic activity of X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms:
1.16.3.1;

Protein crystallography data

The structure of X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms, PDB code: 1kcw was solved by G.L.Card, V.N.Zaitsev, P.F.Lindley, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 12.00 / 3.00
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 213.920, 213.920, 85.630, 90.00, 90.00, 120.00
R / Rfree (%) 22 / 28.6

Copper Binding Sites:

The binding sites of Copper atom in the X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms (pdb code 1kcw). This binding sites where shown within 5.0 Angstroms radius around Copper atom.
In total 8 binding sites of Copper where determined in the X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms, PDB code: 1kcw:
Jump to Copper binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Copper binding site 1 out of 8 in 1kcw

Go back to Copper Binding Sites List in 1kcw
Copper binding site 1 out of 8 in the X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 1 of X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cu1049

b:34.2
occ:1.00
 SG A:CYS319 2.0 30.4 1.0
ND1 A:HIS324 2.0 25.9 1.0
ND1 A:HIS276 2.1 45.2 1.0
CE1 A:HIS276 2.9 45.2 1.0
CG A:HIS324 3.0 25.9 1.0
CE1 A:HIS324 3.1 25.9 1.0
CG A:HIS276 3.1 45.2 1.0
CB A:HIS324 3.3 25.9 1.0
CB A:CYS319 3.3 30.4 1.0
CA A:HIS276 3.5 22.4 1.0
CB A:HIS276 3.5 45.2 1.0
CD1 A:LEU329 3.7 27.1 1.0
O A:VAL275 3.7 28.8 1.0
CB A:ASN321 4.0 33.6 1.0
NE2 A:HIS276 4.0 45.2 1.0
CD2 A:HIS276 4.2 45.2 1.0
CD2 A:HIS324 4.2 25.9 1.0
N A:HIS276 4.2 22.4 1.0
NE2 A:HIS324 4.2 25.9 1.0
C A:VAL275 4.3 28.8 1.0
N A:ALA277 4.5 41.3 1.0
C A:HIS276 4.5 22.4 1.0
ND2 A:ASN321 4.6 33.6 1.0
CG A:ASN321 4.6 33.6 1.0
CA A:CYS319 4.6 35.7 1.0
CD2 A:PHE202 4.8 16.5 1.0
CA A:HIS324 4.8 30.1 1.0
O A:CYS319 4.9 35.7 1.0
CG A:LEU329 4.9 27.1 1.0

Copper binding site 2 out of 8 in 1kcw

Go back to Copper Binding Sites List in 1kcw
Copper binding site 2 out of 8 in the X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 2 of X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cu1050

b:46.4
occ:1.00
 O A:O1057 1.9 6.9 1.0
NE2 A:HIS1020 2.1 46.2 1.0
NE2 A:HIS980 2.1 35.4 1.0
NE2 A:HIS163 2.1 27.9 1.0
CE1 A:HIS980 2.2 35.4 1.0
CE1 A:HIS1020 2.7 46.2 1.0
CD2 A:HIS163 3.0 27.9 1.0
CE1 A:HIS163 3.2 27.9 1.0
CD2 A:HIS1020 3.4 46.2 1.0
CD2 A:HIS980 3.5 35.4 1.0
ND1 A:HIS980 3.5 35.4 1.0
CU A:CU1051 3.7 44.8 1.0
ND1 A:HIS1020 4.0 46.2 1.0
CG A:HIS980 4.1 35.4 1.0
CU A:CU1052 4.2 31.1 1.0
CG A:HIS163 4.2 27.9 1.0
CD2 A:HIS978 4.3 40.5 1.0
ND1 A:HIS163 4.3 27.9 1.0
CG A:HIS1020 4.3 46.2 1.0
CE1 A:HIS161 4.6 26.7 1.0
CD2 A:LEU1018 4.6 9.9 1.0
CD2 A:HIS101 4.6 46.6 1.0
NE2 A:HIS101 4.7 46.6 1.0
NE2 A:HIS1022 4.9 33.5 1.0
NE2 A:HIS978 4.9 40.5 1.0
NE2 A:HIS161 4.9 26.7 1.0

Copper binding site 3 out of 8 in 1kcw

Go back to Copper Binding Sites List in 1kcw
Copper binding site 3 out of 8 in the X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 3 of X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cu1051

b:44.8
occ:1.00
 O A:O1057 1.9 6.9 1.0
NE2 A:HIS103 2.1 24.1 1.0
NE2 A:HIS1022 2.1 33.5 1.0
NE2 A:HIS161 2.1 26.7 1.0
CE1 A:HIS161 2.7 26.7 1.0
CE1 A:HIS103 2.9 24.1 1.0
CE1 A:HIS1022 3.0 33.5 1.0
CD2 A:HIS1022 3.2 33.5 1.0
CD2 A:HIS103 3.2 24.1 1.0
CD2 A:HIS161 3.5 26.7 1.0
CU A:CU1052 3.5 31.1 1.0
CU A:CU1050 3.7 46.4 1.0
CD2 A:HIS978 4.0 40.5 1.0
ND1 A:HIS161 4.0 26.7 1.0
NE2 A:HIS980 4.1 35.4 1.0
ND1 A:HIS1022 4.1 33.5 1.0
ND1 A:HIS103 4.1 24.1 1.0
NE2 A:HIS978 4.1 40.5 1.0
CG A:HIS1022 4.2 33.5 1.0
CG A:HIS103 4.3 24.1 1.0
CG A:HIS161 4.4 26.7 1.0
CD2 A:HIS101 4.5 46.6 1.0
CE1 A:HIS1020 4.6 46.2 1.0
NE2 A:HIS101 4.7 46.6 1.0
CG A:HIS978 4.7 40.5 1.0
CD2 A:HIS980 4.9 35.4 1.0
CE1 A:HIS978 4.9 40.5 1.0
CD2 A:HIS163 4.9 27.9 1.0
NE2 A:HIS1020 4.9 46.2 1.0

Copper binding site 4 out of 8 in 1kcw

Go back to Copper Binding Sites List in 1kcw
Copper binding site 4 out of 8 in the X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 4 of X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cu1052

b:31.1
occ:1.00
 NE2 A:HIS101 2.1 46.6 1.0
NE2 A:HIS978 2.1 40.5 1.0
O A:O1058 2.1 2.0 1.0
CD2 A:HIS980 2.3 35.4 1.0
NE2 A:HIS980 2.7 35.4 1.0
CD2 A:HIS101 2.9 46.6 1.0
CD2 A:HIS978 3.0 40.5 1.0
O A:O1057 3.1 6.9 1.0
CE1 A:HIS978 3.1 40.5 1.0
CE1 A:HIS101 3.2 46.6 1.0
CD2 A:HIS103 3.3 24.1 1.0
NE2 A:HIS103 3.3 24.1 1.0
CU A:CU1051 3.5 44.8 1.0
CG A:HIS980 3.7 35.4 1.0
CG A:HIS103 3.8 24.1 1.0
CE1 A:HIS103 3.8 24.1 1.0
CE1 A:HIS980 4.0 35.4 1.0
ND1 A:HIS103 4.0 24.1 1.0
CG A:HIS101 4.1 46.6 1.0
CG A:HIS978 4.1 40.5 1.0
CU A:CU1050 4.2 46.4 1.0
ND1 A:HIS978 4.2 40.5 1.0
ND1 A:HIS101 4.2 46.6 1.0
O A:SER102 4.2 51.8 1.0
ND1 A:HIS980 4.4 35.4 1.0
CA A:HIS980 4.5 26.3 1.0
NE2 A:HIS161 4.5 26.7 1.0
CA A:HIS103 4.5 53.7 1.0
CB A:HIS980 4.6 35.4 1.0
CB A:HIS103 4.7 24.1 1.0
C A:SER102 5.0 51.8 1.0

Copper binding site 5 out of 8 in 1kcw

Go back to Copper Binding Sites List in 1kcw
Copper binding site 5 out of 8 in the X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 5 of X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cu1053

b:34.5
occ:1.00
 SG A:CYS680 2.0 38.6 1.0
ND1 A:HIS685 2.1 19.6 1.0
ND1 A:HIS637 2.1 23.9 1.0
CG A:HIS637 2.8 23.9 1.0
CB A:HIS637 2.9 23.9 1.0
CG A:HIS685 3.0 19.6 1.0
SD A:MET690 3.1 37.1 1.0
CE1 A:HIS685 3.1 19.6 1.0
CB A:CYS680 3.2 38.6 1.0
CE1 A:HIS637 3.2 23.9 1.0
CB A:HIS685 3.3 19.6 1.0
CA A:HIS637 3.5 28.3 1.0
CE A:MET690 3.8 37.1 1.0
CD2 A:HIS637 4.1 23.9 1.0
OG1 A:THR682 4.2 12.8 1.0
O A:VAL636 4.2 27.0 1.0
CD2 A:HIS685 4.2 19.6 1.0
NE2 A:HIS685 4.2 19.6 1.0
CG2 A:THR682 4.2 12.8 1.0
NE2 A:HIS637 4.3 23.9 1.0
N A:HIS637 4.4 28.3 1.0
CG A:MET690 4.5 37.1 1.0
CA A:CYS680 4.5 17.7 1.0
N A:GLY638 4.6 29.6 1.0
C A:VAL636 4.6 27.0 1.0
C A:HIS637 4.6 28.3 1.0
CA A:HIS685 4.8 17.7 1.0
CB A:THR682 4.8 12.8 1.0
CB A:MET690 5.0 37.1 1.0
O A:THR682 5.0 15.2 1.0
CD1 A:ILE639 5.0 17.2 1.0

Copper binding site 6 out of 8 in 1kcw

Go back to Copper Binding Sites List in 1kcw
Copper binding site 6 out of 8 in the X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 6 of X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cu1054

b:61.6
occ:1.00
 OD2 A:ASP684 2.2 33.0 1.0
OD1 A:ASP684 2.4 33.0 1.0
NE2 A:HIS602 2.4 35.9 1.0
CE1 A:HIS602 2.5 35.9 1.0
CG A:ASP684 2.6 33.0 1.0
CD2 A:HIS602 3.8 35.9 1.0
ND1 A:HIS602 3.8 35.9 1.0
CB A:ASP684 4.1 33.0 1.0
OE2 A:GLU597 4.2 82.0 1.0
OE2 A:GLU971 4.5 46.6 1.0
CG A:HIS602 4.5 35.9 1.0
OE1 A:GLU971 4.6 46.6 1.0
CD A:GLU971 4.8 46.6 1.0

Copper binding site 7 out of 8 in 1kcw

Go back to Copper Binding Sites List in 1kcw
Copper binding site 7 out of 8 in the X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 7 of X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cu1055

b:33.5
occ:1.00
 SG A:CYS1021 2.0 28.4 1.0
ND1 A:HIS1026 2.1 32.3 1.0
ND1 A:HIS975 2.1 19.5 1.0
CB A:CYS1021 2.9 28.4 1.0
CG A:HIS1026 3.0 32.3 1.0
CE1 A:HIS975 3.0 19.5 1.0
CE1 A:HIS1026 3.1 32.3 1.0
O A:LEU974 3.1 37.2 1.0
CG A:HIS975 3.2 19.5 1.0
SD A:MET1031 3.2 32.1 1.0
CB A:HIS1026 3.2 32.3 1.0
CA A:HIS975 3.5 29.4 1.0
CB A:HIS975 3.5 19.5 1.0
CG1 A:VAL1023 4.0 25.6 1.0
C A:LEU974 4.1 37.2 1.0
CD2 A:HIS1026 4.2 32.3 1.0
NE2 A:HIS975 4.2 19.5 1.0
NE2 A:HIS1026 4.2 32.3 1.0
CG A:MET1031 4.3 32.1 1.0
CA A:CYS1021 4.3 23.5 1.0
CD2 A:HIS975 4.3 19.5 1.0
N A:HIS975 4.3 29.4 1.0
CG2 A:VAL1023 4.5 25.6 1.0
C A:HIS975 4.5 29.4 1.0
N A:THR976 4.6 27.3 1.0
CA A:HIS1026 4.8 22.6 1.0
CB A:VAL1023 4.8 25.6 1.0
CE A:MET1031 4.8 32.1 1.0
C A:CYS1021 4.9 23.5 1.0
CB A:MET1031 4.9 32.1 1.0
N A:VAL1023 5.0 20.5 1.0

Copper binding site 8 out of 8 in 1kcw

Go back to Copper Binding Sites List in 1kcw
Copper binding site 8 out of 8 in the X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms


Mono view


Stereo pair view

A full contact list of Copper with other atoms in the Cu binding site number 8 of X-Ray Crystal Structure of Human Ceruloplasmin at 3.0 Angstroms within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cu1056

b:27.6
occ:1.00
 NE2 A:HIS940 2.1 28.3 1.0
OD2 A:ASP1025 2.1 77.3 1.0
CE1 A:HIS940 2.8 28.3 1.0
CG A:ASP1025 3.0 77.3 1.0
OD1 A:ASP1025 3.1 77.3 1.0
CD2 A:HIS940 3.3 28.3 1.0
OE2 A:GLU935 3.4 63.1 1.0
OE2 A:GLU272 4.0 36.9 1.0
ND1 A:HIS940 4.1 28.3 1.0
CG A:HIS940 4.3 28.3 1.0
CB A:ASP1025 4.4 77.3 1.0
CD A:GLU935 4.5 63.1 1.0
OE1 A:GLU272 4.7 36.9 1.0
CD A:GLU272 4.8 36.9 1.0
CD2 A:HIS1026 4.9 32.3 1.0
CB A:LYS938 4.9 41.2 1.0
CG2 A:ILE972 4.9 39.6 1.0

Reference:

I.Zaitseva, V.Zaitsev, G.Card, K.Moshkov, B.Bax, A.Ralph, P.Lindley. The X-Ray Structure of Human Serum Ceruloplasmin at 3.1 Angstrom: Nature of the Copper Centres. J.Biol.Inorg.Chem. V. 1 15 1996.
ISSN: ISSN 0949-8257
Page generated: Tue Jul 30 22:10:46 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy