Copper in the structure of The Structure of Holo Type Human Cu, Zn Superoxide Dismutase (pdb 1hl5)

The binding sites of Copper atom in the structure of The Structure of Holo Type Human Cu, Zn Superoxide Dismutase (pdb code 1hl5). This binding sites where shown with 5.0 Angstroms radius around Copper atom. The 1hl5 structure was solved by R.W.STRANGE, S.ANTONYUK, M.A.HOUGH, P.DOUCETTE, J.RODRIGUEZ, P.J.HART, L.J.HAYWARD, J.S.VALENTINE, S.S.HASNAIN, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 50.0-1.8 Space group P1211 a (A) 76.871 b (A) 172.380 c (A) 112.450 alpha (°) 90.00 beta (°) 93.45 gamma (°) 90.00 Rfactor (%) 18.5 Rfree (%) 22.2 Copper Binding Sites: Copper binding site 1 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: His46, A: His48, A: His63, A: Val118, A: His120, A: Hoh2047, A: Hoh2103, A: Hoh2105, conact list: Atom Atom Distance (A) Cu NE2 A:His46 4.18 Cu N A:His46 4.79 Cu CB A:His46 3.37 Cu ND1 A:His46 2.14 Cu CD2 A:His46 4.20 Cu CE1 A:His46 3.09 Cu CG A:His46 3.08 Cu CA A:His46 4.64 Cu NE2 A:His48 2.13 Cu ND1 A:His48 4.04 Cu CD2 A:His48 3.29 Cu CE1 A:His48 2.83 Cu CG A:His48 4.28 Cu NE2 A:His63 2.46 Cu ND1 A:His63 4.50 Cu CD2 A:His63 3.08 Cu CE1 A:His63 3.57 Cu CG A:His63 4.30 Cu CB A:Val118 4.65 Cu CG1 A:Val118 4.60 Cu NE2 A:His120 2.12 Cu ND1 A:His120 4.19 Cu CD2 A:His120 3.06 Cu CE1 A:His120 3.10 Cu CG A:His120 4.20 Cu O A:Hoh2047 2.65 Cu O A:Hoh2103 4.86 Cu O A:Hoh2105 4.73 interactive model: Copper binding site 2 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: B: His46, B: His48, B: His63, B: Val118, B: His120, B: Hoh2083, B: Hoh2139, B: Hoh2144, conact list: Atom Atom Distance (A) Cu NE2 B:His46 4.17 Cu N B:His46 4.82 Cu CB B:His46 3.37 Cu ND1 B:His46 2.12 Cu CD2 B:His46 4.20 Cu CE1 B:His46 3.06 Cu CG B:His46 3.08 Cu CA B:His46 4.69 Cu NE2 B:His48 2.11 Cu ND1 B:His48 3.98 Cu CD2 B:His48 3.29 Cu CE1 B:His48 2.76 Cu CG B:His48 4.25 Cu NE2 B:His63 2.60 Cu ND1 B:His63 4.63 Cu CD2 B:His63 3.23 Cu CE1 B:His63 3.69 Cu CG B:His63 4.44 Cu CB B:Val118 4.59 Cu CG1 B:Val118 4.66 Cu NE2 B:His120 2.12 Cu ND1 B:His120 4.16 Cu CD2 B:His120 3.12 Cu CE1 B:His120 3.03 Cu CG B:His120 4.24 Cu O B:Hoh2083 2.47 Cu O B:Hoh2139 4.98 Cu O B:Hoh2144 4.56 interactive model: Copper binding site 3 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 3 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: C: His46, C: His48, C: His63, C: Val118, C: His120, C: Hoh2074, C: Hoh2135, conact list: Atom Atom Distance (A) Cu NE2 C:His46 4.21 Cu N C:His46 4.78 Cu CB C:His46 3.32 Cu ND1 C:His46 2.13 Cu CD2 C:His46 4.19 Cu CE1 C:His46 3.13 Cu CG C:His46 3.04 Cu CA C:His46 4.65 Cu NE2 C:His48 2.11 Cu ND1 C:His48 4.03 Cu CD2 C:His48 3.27 Cu CE1 C:His48 2.82 Cu CG C:His48 4.26 Cu NE2 C:His63 2.72 Cu ND1 C:His63 4.68 Cu CD2 C:His63 3.27 Cu CE1 C:His63 3.77 Cu CG C:His63 4.46 Cu CB C:Val118 4.53 Cu CG1 C:Val118 4.63 Cu NE2 C:His120 2.19 Cu ND1 C:His120 4.21 Cu CD2 C:His120 3.09 Cu CE1 C:His120 3.13 Cu CG C:His120 4.23 Cu O C:Hoh2074 2.52 Cu O C:Hoh2135 4.68 interactive model: Copper binding site 4 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 4 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: D: His46, D: His48, D: His63, D: Val118, D: His120, D: Hoh2049, D: Hoh2095, conact list: Atom Atom Distance (A) Cu NE2 D:His46 4.21 Cu N D:His46 4.81 Cu CB D:His46 3.45 Cu ND1 D:His46 2.17 Cu CD2 D:His46 4.26 Cu CE1 D:His46 3.11 Cu CG D:His46 3.14 Cu CA D:His46 4.71 Cu NE2 D:His48 2.07 Cu ND1 D:His48 4.05 Cu CD2 D:His48 3.18 Cu CE1 D:His48 2.87 Cu CG D:His48 4.22 Cu NE2 D:His63 2.60 Cu ND1 D:His63 4.62 Cu CD2 D:His63 3.23 Cu CE1 D:His63 3.68 Cu CG D:His63 4.43 Cu CB D:Val118 4.53 Cu CG1 D:Val118 4.43 Cu NE2 D:His120 2.14 Cu ND1 D:His120 4.23 Cu CD2 D:His120 2.97 Cu CE1 D:His120 3.20 Cu CG D:His120 4.16 Cu O D:Hoh2049 2.70 Cu O D:Hoh2095 4.73 interactive model: Copper binding site 5 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 5 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: E: His46, E: His48, E: His63, E: Val118, E: His120, E: Hoh2052, E: Hoh2100, E: Hoh2103, conact list: Atom Atom Distance (A) Cu NE2 E:His46 4.19 Cu N E:His46 4.81 Cu CB E:His46 3.33 Cu ND1 E:His46 2.15 Cu CD2 E:His46 4.19 Cu CE1 E:His46 3.11 Cu CG E:His46 3.06 Cu CA E:His46 4.65 Cu NE2 E:His48 2.10 Cu ND1 E:His48 4.05 Cu CD2 E:His48 3.26 Cu CE1 E:His48 2.84 Cu CG E:His48 4.27 Cu NE2 E:His63 2.52 Cu ND1 E:His63 4.54 Cu CD2 E:His63 3.19 Cu CE1 E:His63 3.58 Cu CG E:His63 4.38 Cu CB E:Val118 4.59 Cu CG1 E:Val118 4.65 Cu NE2 E:His120 2.16 Cu ND1 E:His120 4.21 Cu CD2 E:His120 3.11 Cu CE1 E:His120 3.11 Cu CG E:His120 4.24 Cu O E:Hoh2052 2.66 Cu O E:Hoh2100 4.99 Cu O E:Hoh2103 4.68 interactive model: Copper binding site 6 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 6 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: F: His46, F: His48, F: His63, F: Val118, F: His120, F: Hoh2040, F: Hoh2081, F: Hoh2087, conact list: Atom Atom Distance (A) Cu NE2 F:His46 4.11 Cu N F:His46 4.80 Cu CB F:His46 3.32 Cu ND1 F:His46 2.04 Cu CD2 F:His46 4.13 Cu CE1 F:His46 3.01 Cu CG F:His46 3.00 Cu CA F:His46 4.62 Cu NE2 F:His48 2.09 Cu ND1 F:His48 4.03 Cu CD2 F:His48 3.23 Cu CE1 F:His48 2.84 Cu CG F:His48 4.24 Cu NE2 F:His63 2.51 Cu ND1 F:His63 4.55 Cu CD2 F:His63 3.17 Cu CE1 F:His63 3.59 Cu CG F:His63 4.38 Cu CB F:Val118 4.60 Cu CG1 F:Val118 4.65 Cu NE2 F:His120 2.14 Cu ND1 F:His120 4.19 Cu CD2 F:His120 3.06 Cu CE1 F:His120 3.12 Cu CG F:His120 4.20 Cu O F:Hoh2040 2.72 Cu O F:Hoh2081 5.00 Cu O F:Hoh2087 4.64 interactive model: Copper binding site 7 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 7 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: G: His46, G: His48, G: His63, G: Val118, G: His120, G: Hoh2010, G: Hoh2021, G: Hoh2022, conact list: Atom Atom Distance (A) Cu NE2 G:His46 4.14 Cu N G:His46 4.79 Cu CB G:His46 3.34 Cu ND1 G:His46 2.05 Cu CD2 G:His46 4.17 Cu CE1 G:His46 3.03 Cu CG G:His46 3.04 Cu CA G:His46 4.62 Cu NE2 G:His48 2.14 Cu ND1 G:His48 4.07 Cu CD2 G:His48 3.30 Cu CE1 G:His48 2.86 Cu CG G:His48 4.30 Cu NE2 G:His63 2.70 Cu ND1 G:His63 4.70 Cu CD2 G:His63 3.35 Cu CE1 G:His63 3.75 Cu CG G:His63 4.53 Cu CB G:Val118 4.57 Cu CG1 G:Val118 4.55 Cu NE2 G:His120 1.96 Cu ND1 G:His120 3.93 Cu CD2 G:His120 3.06 Cu CE1 G:His120 2.77 Cu CG G:His120 4.09 Cu O G:Hoh2010 1.96 Cu O G:Hoh2021 4.47 Cu O G:Hoh2022 2.01 interactive model: Copper binding site 8 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 8 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: H: His46, H: His48, H: His63, H: Val118, H: His120, H: Hoh2050, H: Hoh2109, conact list: Atom Atom Distance (A) Cu NE2 H:His46 4.15 Cu N H:His46 4.74 Cu CB H:His46 3.24 Cu ND1 H:His46 2.13 Cu CD2 H:His46 4.11 Cu CE1 H:His46 3.11 Cu CG H:His46 2.97 Cu CA H:His46 4.57 Cu NE2 H:His48 2.10 Cu ND1 H:His48 4.11 Cu CD2 H:His48 3.20 Cu CE1 H:His48 2.93 Cu CG H:His48 4.26 Cu NE2 H:His63 2.52 Cu ND1 H:His63 4.58 Cu CD2 H:His63 3.14 Cu CE1 H:His63 3.64 Cu CG H:His63 4.36 Cu CB H:Val118 4.58 Cu CG1 H:Val118 4.58 Cu NE2 H:His120 2.11 Cu ND1 H:His120 4.16 Cu CD2 H:His120 3.03 Cu CE1 H:His120 3.09 Cu CG H:His120 4.17 Cu O H:Hoh2050 2.74 Cu O H:Hoh2109 4.70 interactive model: Copper binding site 9 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 9 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: I: His46, I: His48, I: His63, I: Val118, I: His120, I: Hoh2069, I: Hoh2125, I: Hoh2133, conact list: Atom Atom Distance (A) Cu NE2 I:His46 4.19 Cu N I:His46 4.77 Cu CB I:His46 3.31 Cu ND1 I:His46 2.12 Cu CD2 I:His46 4.18 Cu CE1 I:His46 3.11 Cu CG I:His46 3.03 Cu CA I:His46 4.62 Cu NE2 I:His48 2.11 Cu ND1 I:His48 4.09 Cu CD2 I:His48 3.20 Cu CE1 I:His48 2.93 Cu CG I:His48 4.25 Cu NE2 I:His63 2.67 Cu ND1 I:His63 4.67 Cu CD2 I:His63 3.24 Cu CE1 I:His63 3.75 Cu CG I:His63 4.46 Cu CB I:Val118 4.47 Cu CG1 I:Val118 4.54 Cu NE2 I:His120 2.03 Cu ND1 I:His120 4.05 Cu CD2 I:His120 3.03 Cu CE1 I:His120 2.94 Cu CG I:His120 4.12 Cu O I:Hoh2069 2.87 Cu O I:Hoh2125 3.55 Cu O I:Hoh2133 4.83 interactive model: Copper binding site 10 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 10 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: J: His46, J: His48, J: His63, J: Val118, J: His120, J: Hoh2064, J: Hoh2124, conact list: Atom Atom Distance (A) Cu NE2 J:His46 4.20 Cu N J:His46 4.86 Cu CB J:His46 3.43 Cu ND1 J:His46 2.15 Cu CD2 J:His46 4.23 Cu CE1 J:His46 3.10 Cu CG J:His46 3.11 Cu CA J:His46 4.72 Cu NE2 J:His48 2.09 Cu ND1 J:His48 4.03 Cu CD2 J:His48 3.22 Cu CE1 J:His48 2.85 Cu CG J:His48 4.23 Cu NE2 J:His63 2.61 Cu ND1 J:His63 4.67 Cu CD2 J:His63 3.23 Cu CE1 J:His63 3.73 Cu CG J:His63 4.47 Cu CB J:Val118 4.54 Cu CG1 J:Val118 4.61 Cu NE2 J:His120 2.14 Cu ND1 J:His120 4.19 Cu CD2 J:His120 3.07 Cu CE1 J:His120 3.11 Cu CG J:His120 4.20 Cu O J:Hoh2064 2.63 Cu O J:Hoh2124 4.72 interactive model: Copper binding site 11 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 11 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: K: His46, K: His48, K: His63, K: Val118, K: His120, K: Hoh2063, K: Hoh2136, K: Hoh2141, conact list: Atom Atom Distance (A) Cu NE2 K:His46 4.17 Cu N K:His46 4.85 Cu CB K:His46 3.36 Cu ND1 K:His46 2.11 Cu CD2 K:His46 4.19 Cu CE1 K:His46 3.07 Cu CG K:His46 3.06 Cu CA K:His46 4.70 Cu NE2 K:His48 2.11 Cu ND1 K:His48 4.06 Cu CD2 K:His48 3.26 Cu CE1 K:His48 2.85 Cu CG K:His48 4.27 Cu NE2 K:His63 2.48 Cu ND1 K:His63 4.55 Cu CD2 K:His63 3.15 Cu CE1 K:His63 3.59 Cu CG K:His63 4.37 Cu CB K:Val118 4.62 Cu CG1 K:Val118 4.72 Cu NE2 K:His120 2.15 Cu ND1 K:His120 4.20 Cu CD2 K:His120 3.10 Cu CE1 K:His120 3.11 Cu CG K:His120 4.22 Cu O K:Hoh2063 2.65 Cu O K:Hoh2136 4.99 Cu O K:Hoh2141 4.54 interactive model: Copper binding site 12 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 12 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: L: His46, L: His48, L: His63, L: Val118, L: His120, L: Hoh2049, L: Hoh2106, conact list: Atom Atom Distance (A) Cu NE2 L:His46 4.15 Cu N L:His46 4.69 Cu CB L:His46 3.39 Cu ND1 L:His46 2.09 Cu CD2 L:His46 4.18 Cu CE1 L:His46 3.04 Cu CG L:His46 3.07 Cu CA L:His46 4.60 Cu NE2 L:His48 2.05 Cu ND1 L:His48 4.02 Cu CD2 L:His48 3.18 Cu CE1 L:His48 2.83 Cu CG L:His48 4.21 Cu NE2 L:His63 2.82 Cu ND1 L:His63 4.72 Cu CD2 L:His63 3.33 Cu CE1 L:His63 3.84 Cu CG L:His63 4.50 Cu CB L:Val118 4.44 Cu CG1 L:Val118 4.57 Cu NE2 L:His120 2.02 Cu ND1 L:His120 4.08 Cu CD2 L:His120 2.97 Cu CE1 L:His120 2.99 Cu CG L:His120 4.10 Cu O L:Hoh2049 3.15 Cu O L:Hoh2106 4.93 interactive model: Copper binding site 13 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 13 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: M: His46, M: His48, M: His63, M: Val118, M: His120, M: Hoh2041, M: Hoh2090, conact list: Atom Atom Distance (A) Cu NE2 M:His46 4.17 Cu N M:His46 4.81 Cu CB M:His46 3.30 Cu ND1 M:His46 2.11 Cu CD2 M:His46 4.18 Cu CE1 M:His46 3.09 Cu CG M:His46 3.04 Cu CA M:His46 4.62 Cu NE2 M:His48 2.11 Cu ND1 M:His48 4.08 Cu CD2 M:His48 3.21 Cu CE1 M:His48 2.90 Cu CG M:His48 4.25 Cu NE2 M:His63 2.53 Cu ND1 M:His63 4.51 Cu CD2 M:His63 3.19 Cu CE1 M:His63 3.57 Cu CG M:His63 4.36 Cu CB M:Val118 4.60 Cu CG1 M:Val118 4.69 Cu NE2 M:His120 2.10 Cu ND1 M:His120 4.15 Cu CD2 M:His120 3.06 Cu CE1 M:His120 3.05 Cu CG M:His120 4.19 Cu O M:Hoh2041 2.62 Cu O M:Hoh2090 4.64 interactive model: Copper binding site 14 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 14 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: N: His46, N: His48, N: His63, N: Val118, N: His120, N: Hoh2038, N: Hoh2082, conact list: Atom Atom Distance (A) Cu NE2 N:His46 4.20 Cu N N:His46 4.75 Cu CB N:His46 3.32 Cu ND1 N:His46 2.12 Cu CD2 N:His46 4.20 Cu CE1 N:His46 3.10 Cu CG N:His46 3.06 Cu CA N:His46 4.62 Cu NE2 N:His48 2.07 Cu ND1 N:His48 4.07 Cu CD2 N:His48 3.16 Cu CE1 N:His48 2.90 Cu CG N:His48 4.22 Cu NE2 N:His63 2.72 Cu ND1 N:His63 4.64 Cu CD2 N:His63 3.29 Cu CE1 N:His63 3.75 Cu CG N:His63 4.45 Cu CB N:Val118 4.46 Cu CG1 N:Val118 4.54 Cu NE2 N:His120 2.04 Cu ND1 N:His120 4.06 Cu CD2 N:His120 3.05 Cu CE1 N:His120 2.94 Cu CG N:His120 4.14 Cu O N:Hoh2038 2.65 Cu O N:Hoh2082 4.74 interactive model: Copper binding site 15 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 15 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: O: His46, O: His48, O: His63, O: Val118, O: His120, O: Hoh2024, conact list: Atom Atom Distance (A) Cu NE2 O:His46 4.31 Cu N O:His46 4.76 Cu CB O:His46 3.21 Cu ND1 O:His46 2.19 Cu CD2 O:His46 4.23 Cu CE1 O:His46 3.26 Cu CG O:His46 3.04 Cu CA O:His46 4.55 Cu NE2 O:His48 2.18 Cu ND1 O:His48 4.20 Cu CD2 O:His48 3.19 Cu CE1 O:His48 3.07 Cu CG O:His48 4.28 Cu NE2 O:His63 2.60 Cu ND1 O:His63 4.53 Cu CD2 O:His63 3.17 Cu CE1 O:His63 3.64 Cu CG O:His63 4.34 Cu CB O:Val118 4.54 Cu CG1 O:Val118 4.62 Cu NE2 O:His120 2.10 Cu ND1 O:His120 4.17 Cu CD2 O:His120 2.97 Cu CE1 O:His120 3.13 Cu CG O:His120 4.14 Cu O O:Hoh2024 4.61 interactive model: Copper binding site 16 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 16 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: P: His46, P: His48, P: His63, P: Val118, P: His120, conact list: Atom Atom Distance (A) Cu O P:His46 4.86 Cu NE2 P:His46 4.14 Cu N P:His46 4.47 Cu CB P:His46 3.12 Cu ND1 P:His46 2.07 Cu CD2 P:His46 4.07 Cu C P:His46 4.76 Cu CE1 P:His46 3.12 Cu CG P:His46 2.91 Cu CA P:His46 4.29 Cu NE2 P:His48 2.12 Cu ND1 P:His48 4.09 Cu CD2 P:His48 3.07 Cu CE1 P:His48 3.02 Cu CG P:His48 4.15 Cu NE2 P:His63 2.33 Cu ND1 P:His63 4.19 Cu CD2 P:His63 2.84 Cu CE1 P:His63 3.36 Cu CG P:His63 3.97 Cu CB P:Val118 4.73 Cu CG1 P:Val118 4.88 Cu NE2 P:His120 2.57 Cu ND1 P:His120 4.64 Cu CD2 P:His120 3.29 Cu CE1 P:His120 3.65 Cu CG P:His120 4.50 interactive model: Copper binding site 17 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 17 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: Q: His46, Q: His48, Q: His63, Q: Val118, Q: His120, Q: Hoh2040, Q: Hoh2076, conact list: Atom Atom Distance (A) Cu NE2 Q:His46 4.13 Cu N Q:His46 4.79 Cu CB Q:His46 3.40 Cu ND1 Q:His46 2.08 Cu CD2 Q:His46 4.17 Cu CE1 Q:His46 3.01 Cu CG Q:His46 3.07 Cu CA Q:His46 4.64 Cu NE2 Q:His48 2.06 Cu ND1 Q:His48 3.98 Cu CD2 Q:His48 3.23 Cu CE1 Q:His48 2.77 Cu CG Q:His48 4.22 Cu NE2 Q:His63 2.63 Cu ND1 Q:His63 4.58 Cu CD2 Q:His63 3.22 Cu CE1 Q:His63 3.67 Cu CG Q:His63 4.40 Cu CB Q:Val118 4.57 Cu CG1 Q:Val118 4.64 Cu NE2 Q:His120 2.12 Cu ND1 Q:His120 4.20 Cu CD2 Q:His120 3.01 Cu CE1 Q:His120 3.14 Cu CG Q:His120 4.17 Cu O Q:Hoh2040 2.74 Cu O Q:Hoh2076 4.79 interactive model: Copper binding site 18 out of 18 in 1hl5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 18 of Copper in the PDB 1hl5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: S: His46, S: His48, S: His63, S: Val118, S: His120, conact list: Atom Atom Distance (A) Cu NE2 S:His46 4.23 Cu N S:His46 4.75 Cu CB S:His46 3.31 Cu ND1 S:His46 2.18 Cu CD2 S:His46 4.21 Cu CE1 S:His46 3.17 Cu CG S:His46 3.08 Cu CA S:His46 4.55 Cu NE2 S:His48 2.02 Cu ND1 S:His48 3.94 Cu CD2 S:His48 3.23 Cu CE1 S:His48 2.71 Cu CG S:His48 4.21 Cu NE2 S:His63 2.52 Cu ND1 S:His63 4.43 Cu CD2 S:His63 3.16 Cu CE1 S:His63 3.51 Cu CG S:His63 4.29 Cu CB S:Val118 4.62 Cu CG1 S:Val118 4.53 Cu NE2 S:His120 2.20 Cu ND1 S:His120 4.29 Cu CD2 S:His120 3.06 Cu CE1 S:His120 3.24 Cu CG S:His120 4.24 interactive model: