Copper in the structure of X-Ray Crystal Structure of Copper-Bound F93I/F95M/W97V Carbonic Anhydrase (Caii) Variant (pdb 1fr4)

The binding sites of Copper atom in the structure of X-Ray Crystal Structure of Copper-Bound F93I/F95M/W97V Carbonic Anhydrase (Caii) Variant (pdb code 1fr4). This binding sites where shown with 5.0 Angstroms radius around Copper atom. The 1fr4 structure was solved by J.D.COX, J.A.HUNT, K.M.COMPHER, C.A.FIERKE, D.W.CHRISTIANSON, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 20.0-1.6 Space group P1211 a (A) 42.000 b (A) 41.200 c (A) 72.100 alpha (°) 90.00 beta (°) 103.10 gamma (°) 90.00 Rfactor (%) 22.1 Rfree (%) 25.9 Copper Binding Sites: Copper binding site 1 out of 1 in 1fr4 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Copper in the PDB 1fr4. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Copper atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: His94, A: His96, A: Glu106, A: His119, A: Thr199, A: So4990, A: Hoh309, A: Hoh370, A: Hoh394, conact list: Atom Atom Distance (A) Cu NE2 A:His94 2.13 Cu ND1 A:His94 4.24 Cu CD2 A:His94 3.06 Cu CE1 A:His94 3.15 Cu CG A:His94 4.23 Cu NE2 A:His96 2.13 Cu ND1 A:His96 4.24 Cu CD2 A:His96 3.04 Cu CE1 A:His96 3.16 Cu CG A:His96 4.22 Cu OE1 A:Glu106 3.98 Cu CD A:Glu106 4.73 Cu NE2 A:His119 4.24 Cu CB A:His119 3.54 Cu ND1 A:His119 2.18 Cu CD2 A:His119 4.31 Cu CE1 A:His119 3.10 Cu CG A:His119 3.20 Cu OG1 A:Thr199 3.74 Cu S A:So4990 3.31 Cu O1 A:So4990 3.47 Cu O2 A:So4990 3.73 Cu O4 A:So4990 2.38 Cu O3 A:So4990 4.67 Cu O A:Hoh309 2.23 Cu O A:Hoh370 4.51 Cu O A:Hoh394 4.05 interactive model: