Copper in PDB 7xmb: Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113
Enzymatic activity of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113
All present enzymatic activity of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113:
7.1.1.9;
7.1.1.9;
Protein crystallography data
The structure of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113, PDB code: 7xmb
was solved by
Y.Nishida,
K.Shinzawa-Itoh,
N.Mizuno,
T.Kumasaka,
S.Yoshikawa,
T.Tsukihara,
Y.Shintani,
S.Takashima,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 29.98 / 2.20 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 182.097, 204.337, 177.933, 90, 90, 90 |
| R / Rfree (%) | 17.8 / 20.4 |
Other elements in 7xmb:
The structure of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113 also contains other interesting chemical elements:
| Sodium | (Na) | 2 atoms |
| Magnesium | (Mg) | 2 atoms |
| Iron | (Fe) | 4 atoms |
| Zinc | (Zn) | 2 atoms |
Copper Binding Sites:
The binding sites of Copper atom in the Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113
(pdb code 7xmb). This binding sites where shown within
5.0 Angstroms radius around Copper atom.
In total 6 binding sites of Copper where determined in the Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113, PDB code: 7xmb:
Jump to Copper binding site number: 1; 2; 3; 4; 5; 6;
In total 6 binding sites of Copper where determined in the Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113, PDB code: 7xmb:
Jump to Copper binding site number: 1; 2; 3; 4; 5; 6;
Copper binding site 1 out of 6 in 7xmb
Go back to
Copper Binding Sites List in 7xmb
Copper binding site 1 out
of 6 in the Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Copper with other atoms in the Cu binding
site number 1 of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113 within 5.0Å range:
|
Copper binding site 2 out of 6 in 7xmb
Go back to
Copper Binding Sites List in 7xmb
Copper binding site 2 out
of 6 in the Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Copper with other atoms in the Cu binding
site number 2 of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113 within 5.0Å range:
|
Copper binding site 3 out of 6 in 7xmb
Go back to
Copper Binding Sites List in 7xmb
Copper binding site 3 out
of 6 in the Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Copper with other atoms in the Cu binding
site number 3 of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113 within 5.0Å range:
|
Copper binding site 4 out of 6 in 7xmb
Go back to
Copper Binding Sites List in 7xmb
Copper binding site 4 out
of 6 in the Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Copper with other atoms in the Cu binding
site number 4 of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113 within 5.0Å range:
|
Copper binding site 5 out of 6 in 7xmb
Go back to
Copper Binding Sites List in 7xmb
Copper binding site 5 out
of 6 in the Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Copper with other atoms in the Cu binding
site number 5 of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113 within 5.0Å range:
|
Copper binding site 6 out of 6 in 7xmb
Go back to
Copper Binding Sites List in 7xmb
Copper binding site 6 out
of 6 in the Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Copper with other atoms in the Cu binding
site number 6 of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113 within 5.0Å range:
|
Reference:
Y.Nishida,
S.Yanagisawa,
R.Morita,
H.Shigematsu,
K.Shinzawa-Itoh,
H.Yuki,
S.Ogasawara,
K.Shimuta,
T.Iwamoto,
C.Nakabayashi,
W.Matsumura,
H.Kato,
C.Gopalasingam,
T.Nagao,
T.Qaqorh,
Y.Takahashi,
S.Yamazaki,
K.Kamiya,
R.Harada,
N.Mizuno,
H.Takahashi,
Y.Akeda,
M.Ohnishi,
Y.Ishii,
T.Kumasaka,
T.Murata,
K.Muramoto,
T.Tosha,
Y.Shiro,
T.Honma,
Y.Shigeta,
M.Kubo,
S.Takashima,
Y.Shintani.
Identifying Antibiotics Based on Structural Differences in the Conserved Allostery From Mitochondrial Heme-Copper Oxidases. Nat Commun V. 13 7591 2022.
ISSN: ESSN 2041-1723
PubMed: 36481732
DOI: 10.1038/S41467-022-34771-Y
Page generated: Wed Jul 31 09:23:37 2024
ISSN: ESSN 2041-1723
PubMed: 36481732
DOI: 10.1038/S41467-022-34771-Y
Last articles
Zn in 9JYWZn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
